ID B4EDH1_BURCJ Unreviewed; 227 AA.
AC B4EDH1;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=DedA family protein {ECO:0000313|EMBL:CAR53579.1};
GN ORFNames=BCAL3255 {ECO:0000313|EMBL:CAR53579.1};
OS Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656 /
OS NCTC 13227 / J2315 / CF5610) (Burkholderia cepacia (strain J2315)).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX NCBI_TaxID=216591 {ECO:0000313|EMBL:CAR53579.1, ECO:0000313|Proteomes:UP000001035};
RN [1] {ECO:0000313|EMBL:CAR53579.1, ECO:0000313|Proteomes:UP000001035}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 /
RC CF5610 {ECO:0000313|Proteomes:UP000001035};
RX PubMed=18931103; DOI=10.1128/JB.01230-08;
RA Holden M.T., Seth-Smith H.M., Crossman L.C., Sebaihia M., Bentley S.D.,
RA Cerdeno-Tarraga A.M., Thomson N.R., Bason N., Quail M.A., Sharp S.,
RA Cherevach I., Churcher C., Goodhead I., Hauser H., Holroyd N., Mungall K.,
RA Scott P., Walker D., White B., Rose H., Iversen P., Mil-Homens D.,
RA Rocha E.P., Fialho A.M., Baldwin A., Dowson C., Barrell B.G., Govan J.R.,
RA Vandamme P., Hart C.A., Mahenthiralingam E., Parkhill J.;
RT "The genome of Burkholderia cenocepacia J2315, an epidemic pathogen of
RT cystic fibrosis patients.";
RL J. Bacteriol. 191:261-277(2009).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU367016};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU367016}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the DedA family. {ECO:0000256|ARBA:ARBA00010792,
CC ECO:0000256|RuleBase:RU367016}.
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DR EMBL; AM747720; CAR53579.1; -; Genomic_DNA.
DR RefSeq; WP_006484968.1; NC_011000.1.
DR AlphaFoldDB; B4EDH1; -.
DR KEGG; bcj:BCAL3255; -.
DR eggNOG; COG0586; Bacteria.
DR HOGENOM; CLU_044208_6_1_4; -.
DR Proteomes; UP000001035; Chromosome 1.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR032818; DedA.
DR InterPro; IPR032816; VTT_dom.
DR PANTHER; PTHR30353; INNER MEMBRANE PROTEIN DEDA-RELATED; 1.
DR PANTHER; PTHR30353:SF0; TRANSMEMBRANE PROTEIN; 1.
DR Pfam; PF09335; SNARE_assoc; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU367016};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU367016};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU367016};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU367016}.
FT TRANSMEM 27..49
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367016"
FT TRANSMEM 69..90
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367016"
FT TRANSMEM 159..179
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367016"
FT TRANSMEM 191..213
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367016"
FT DOMAIN 49..177
FT /note="VTT"
FT /evidence="ECO:0000259|Pfam:PF09335"
SQ SEQUENCE 227 AA; 24822 MW; CD6D209ABD747D7C CRC64;
MDTLLHFVNL VLHIDAFLGD FIRQYGAWVY LVLFLIVFCE TGLVVFPFLP GDSLLFIGGA
FAATGEMNVG LLIVLLLVAA ISGNTVNYMI GRWIGPKVFN THIPVLERFL DRAALQKTHS
FYDKHGGKTI VLARFIPVVR TFAPFVAGAS SMSAARFQLF NVIGALVWVL LLVLLGYFFG
NIPFIRQYLN VIVLVGIGAA VVPVALGAVW KLVRGKQSDN VPKAGGR
//
