ID B4EGN0_BURCJ Unreviewed; 351 AA.
AC B4EGN0;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 83.
DE SubName: Full=4-hydroxythreonine-4-phosphate dehydrogenase {ECO:0000313|EMBL:CAR53962.1};
GN ORFNames=BCAM0106 {ECO:0000313|EMBL:CAR53962.1};
OS Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656 /
OS NCTC 13227 / J2315 / CF5610) (Burkholderia cepacia (strain J2315)).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX NCBI_TaxID=216591 {ECO:0000313|EMBL:CAR53962.1, ECO:0000313|Proteomes:UP000001035};
RN [1] {ECO:0000313|EMBL:CAR53962.1, ECO:0000313|Proteomes:UP000001035}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 /
RC CF5610 {ECO:0000313|Proteomes:UP000001035};
RX PubMed=18931103; DOI=10.1128/JB.01230-08;
RA Holden M.T., Seth-Smith H.M., Crossman L.C., Sebaihia M., Bentley S.D.,
RA Cerdeno-Tarraga A.M., Thomson N.R., Bason N., Quail M.A., Sharp S.,
RA Cherevach I., Churcher C., Goodhead I., Hauser H., Holroyd N., Mungall K.,
RA Scott P., Walker D., White B., Rose H., Iversen P., Mil-Homens D.,
RA Rocha E.P., Fialho A.M., Baldwin A., Dowson C., Barrell B.G., Govan J.R.,
RA Vandamme P., Hart C.A., Mahenthiralingam E., Parkhill J.;
RT "The genome of Burkholderia cenocepacia J2315, an epidemic pathogen of
RT cystic fibrosis patients.";
RL J. Bacteriol. 191:261-277(2009).
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DR EMBL; AM747721; CAR53962.1; -; Genomic_DNA.
DR RefSeq; WP_006482293.1; NC_011001.1.
DR AlphaFoldDB; B4EGN0; -.
DR KEGG; bcj:BCAM0106; -.
DR eggNOG; COG1995; Bacteria.
DR HOGENOM; CLU_040168_0_1_4; -.
DR BioCyc; BCEN216591:G1G1V-4044-MONOMER; -.
DR Proteomes; UP000001035; Chromosome 2.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.718.10; Isopropylmalate Dehydrogenase; 1.
DR InterPro; IPR005255; PdxA_fam.
DR PANTHER; PTHR30004; 4-HYDROXYTHREONINE-4-PHOSPHATE DEHYDROGENASE; 1.
DR PANTHER; PTHR30004:SF3; 4-HYDROXYTHREONINE-4-PHOSPHATE DEHYDROGENASE 2-RELATED; 1.
DR Pfam; PF04166; PdxA; 1.
DR SUPFAM; SSF53659; Isocitrate/Isopropylmalate dehydrogenase-like; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
SQ SEQUENCE 351 AA; 36587 MW; 688F02D5F5E80C6E CRC64;
MHTPSTAATQ PVVALTLGDP AGIGAELIAK LLARPDATAR ANLVLIGDRW LWEAGQRVAG
VTIDVEPVAS LAAVRGRPST ARAAFVAVDT IGAAQVTVGQ ADAAGGRSTL AVLDQCLDAA
LAGDIDAICF APLNKYAMKL GGLRHDDELH HFAEALGVTG YFCEFNTLGE LWTARISSHI
PLKDAAGCLS IERIEQASEL IYRSLLANGV AAPKVAIAAF NPHGGDGGSC GREEVDIIEP
AVRRLQARDW PTDTPFHGPF PADTIFLKAQ AGDYQAIVTM YHDQGQIAIK LLGFSRGVTV
QGGLPVPITT PAHGTAYDIA GRGTADVGAT WQALQIACRM GAARRTAAVS A
//
