ID B4FYI2_MAIZE Unreviewed; 457 AA.
AC B4FYI2;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE SubName: Full=tRNA pseudouridine synthase {ECO:0000313|EMBL:ONL98529.1};
GN ORFNames=ZEAMMB73_Zm00001d029342 {ECO:0000313|EMBL:ONL98529.1};
OS Zea mays (Maize).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX NCBI_TaxID=4577 {ECO:0000313|EMBL:ACF87175.1};
RN [1] {ECO:0000313|EMBL:ACG27836.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=18937034; DOI=10.1007/s11103-008-9415-4;
RA Alexandrov N.N., Brover V.V., Freidin S., Troukhan M.E., Tatarinova T.V.,
RA Zhang H., Swaller T.J., Lu Y.P., Bouck J., Flavell R.B., Feldmann K.A.;
RT "Insights into corn genes derived from large-scale cDNA sequencing.";
RL Plant Mol. Biol. 69:179-194(2009).
RN [2] {ECO:0000313|EMBL:ACF87175.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=B73 {ECO:0000313|EMBL:ACF87175.1};
RX PubMed=19936069; DOI=10.1371/journal.pgen.1000740;
RA Soderlund C., Descour A., Kudrna D., Bomhoff M., Boyd L., Currie J.,
RA Angelova A., Collura K., Wissotski M., Ashley E., Morrow D., Fernandes J.,
RA Walbot V., Yu Y.;
RT "Sequencing, mapping, and analysis of 27,455 maize full-length cDNAs.";
RL PLoS Genet. 5:E1000740-E1000740(2009).
RN [3] {ECO:0000313|EMBL:ONL98529.1, ECO:0000313|Proteomes:UP000007305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. B73 {ECO:0000313|EnsemblPlants:Zm00001eb018490_P001,
RC ECO:0000313|Proteomes:UP000007305};
RC TISSUE=Seedling {ECO:0000313|EMBL:ONL98529.1};
RG Maize Genome Sequencing Project;
RA Ware D.;
RT "Update maize B73 reference genome by single molecule sequencing
RT technologies.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EnsemblPlants:Zm00001eb018490_P001}
RP IDENTIFICATION.
RC STRAIN=cv. B73 {ECO:0000313|EnsemblPlants:Zm00001eb018490_P001};
RG EnsemblPlants;
RL Submitted (MAY-2021) to UniProtKB.
CC -!- SIMILARITY: Belongs to the tRNA pseudouridine synthase TruA family.
CC {ECO:0000256|ARBA:ARBA00009375}.
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DR EMBL; BT042170; ACF87175.1; -; mRNA.
DR EMBL; EU955718; ACG27836.1; -; mRNA.
DR EMBL; CM007647; ONL98529.1; -; Genomic_DNA.
DR EMBL; CM007647; ONL98531.1; -; Genomic_DNA.
DR EMBL; CM007647; ONL98534.1; -; Genomic_DNA.
DR AlphaFoldDB; B4FYI2; -.
DR EnsemblPlants; Zm00001eb018490_T001; Zm00001eb018490_P001; Zm00001eb018490.
DR Gramene; Zm00001eb018490_T001; Zm00001eb018490_P001; Zm00001eb018490.
DR HOGENOM; CLU_014673_2_1_1; -.
DR Proteomes; UP000007305; Chromosome 1.
DR ExpressionAtlas; B4FYI2; baseline and differential.
DR GO; GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0001522; P:pseudouridine synthesis; IEA:InterPro.
DR GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR CDD; cd02569; PseudoU_synth_ScPus3; 1.
DR Gene3D; 3.30.70.660; Pseudouridine synthase I, catalytic domain, C-terminal subdomain; 1.
DR Gene3D; 3.30.70.580; Pseudouridine synthase I, catalytic domain, N-terminal subdomain; 1.
DR HAMAP; MF_00171; TruA; 1.
DR InterPro; IPR020103; PsdUridine_synth_cat_dom_sf.
DR InterPro; IPR001406; PsdUridine_synth_TruA.
DR InterPro; IPR020097; PsdUridine_synth_TruA_a/b_dom.
DR InterPro; IPR020095; PsdUridine_synth_TruA_C.
DR InterPro; IPR041707; Pus3-like.
DR InterPro; IPR020094; TruA/RsuA/RluB/E/F_N.
DR NCBIfam; TIGR00071; hisT_truA; 1.
DR PANTHER; PTHR11142; PSEUDOURIDYLATE SYNTHASE; 1.
DR PANTHER; PTHR11142:SF5; TRNA PSEUDOURIDINE(38_39) SYNTHASE; 1.
DR Pfam; PF01416; PseudoU_synth_1; 1.
DR SUPFAM; SSF55120; Pseudouridine synthase; 1.
PE 1: Evidence at protein level;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Proteomics identification {ECO:0007829|PeptideAtlas:B4FYI2};
KW Reference proteome {ECO:0000313|Proteomes:UP000007305};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT DOMAIN 262..373
FT /note="Pseudouridine synthase I TruA alpha/beta"
FT /evidence="ECO:0000259|Pfam:PF01416"
FT REGION 87..109
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 415..444
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 9..36
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 428..444
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 457 AA; 51705 MW; 4C861EF23A32760B CRC64;
MAAADPETAA ALRGEVAALR MRVQELEAEN QRLARIASTC TCGFKEGSVG SITAHHNVKF
HQNSTMEKDL SSPFDHTVIS NANEMQCNRN ADDNGLPEDS SKHTKRTGRK VGILSHCPKR
LVALKVMYFG QRFYGFSSEG NIEPTVESEI FKALERAKLM VANRKESCYS RCGRTDKGVS
ATGQVISLYL RSNIKDVGGD MLDERSEIDY VKVLNRILPR DIRVLGWCPV PADFHARFTC
LSREYKYLFW KGDLDILEMQ KAASKFIGEH DFRNFCKMDA ANVSNYRRHI TEFTISACDR
RSNNDELCSM TIKGSAFLWH QVRCMVAVLF LIGQGLESPS VVDSLLDIMK TSRKPQYKMA
PELPLILQSC LFDKANFMCS ADASRSLTEH LNDEYRHHML QAEIFHIASS CLPFPEPNSS
ETPQKKRNHI PLLSRETEPS YEERISKVKA KLADNLK
//
