ID B4H185_DROPE Unreviewed; 3708 AA.
AC B4H185;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 102.
DE SubName: Full=GL22528 {ECO:0000313|EMBL:EDW30062.1};
GN Name=Dper\GL22528 {ECO:0000313|EMBL:EDW30062.1};
GN ORFNames=Dper_GL22528 {ECO:0000313|EMBL:EDW30062.1};
OS Drosophila persimilis (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7234 {ECO:0000313|Proteomes:UP000008744};
RN [1] {ECO:0000313|EMBL:EDW30062.1, ECO:0000313|Proteomes:UP000008744}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MSH-3 / Tucson 14011-0111.49
RC {ECO:0000313|Proteomes:UP000008744};
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RA Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B., Markow T.A.,
RA Kaufman T.C., Kellis M., Gelbart W., Iyer V.N., Pollard D.A., Sackton T.B.,
RA Larracuente A.M., Singh N.D., Abad J.P., Abt D.N., Adryan B., Aguade M.,
RA Akashi H., Anderson W.W., Aquadro C.F., Ardell D.H., Arguello R.,
RA Artieri C.G., Barbash D.A., Barker D., Barsanti P., Batterham P.,
RA Batzoglou S., Begun D., Bhutkar A., Blanco E., Bosak S.A., Bradley R.K.,
RA Brand A.D., Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A., Daub J.,
RA David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H., Edwards K.,
RA Eickbush T., Evans J.D., Filipski A., Findeiss S., Freyhult E., Fulton L.,
RA Fulton R., Garcia A.C., Gardiner A., Garfield D.A., Garvin B.E., Gibson G.,
RA Gilbert D., Gnerre S., Godfrey J., Good R., Gotea V., Gravely B.,
RA Greenberg A.J., Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A.,
RA Haerty W., Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A., Hubisz M.J.,
RA Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S., Jeck W.R.,
RA Johnson J., Jones C.D., Jordan W.C., Karpen G.H., Kataoka E.,
RA Keightley P.D., Kheradpour P., Kirkness E.F., Koerich L.B., Kristiansen K.,
RA Kudrna D., Kulathinal R.J., Kumar S., Kwok R., Lander E., Langley C.H.,
RA Lapoint R., Lazzaro B.P., Lee S.J., Levesque L., Li R., Lin C.F., Lin M.F.,
RA Lindblad-Toh K., Llopart A., Long M., Low L., Lozovsky E., Lu J., Luo M.,
RA Machado C.A., Makalowski W., Marzo M., Matsuda M., Matzkin L.,
RA McAllister B., McBride C.S., McKernan B., McKernan K., Mendez-Lago M.,
RA Minx P., Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E.,
RA Negre B., Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S., Pesole G.,
RA Phillippy A.M., Ponting C.P., Pop M., Porcelli D., Powell J.R.,
RA Prohaska S., Pruitt K., Puig M., Quesneville H., Ram K.R., Rand D.,
RA Rasmussen M.D., Reed L.K., Reenan R., Reily A., Remington K.A.,
RA Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H., Rohde C., Rozas J.,
RA Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L., Sanchez-Gracia A.,
RA Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C., Schlenke T.,
RA Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M., Sisneros N.B.,
RA Smith C.D., Smith T.F., Spieth J., Stage D.E., Stark A., Stephan W.,
RA Strausberg R.L., Strempel S., Sturgill D., Sutton G., Sutton G.G., Tao W.,
RA Teichmann S., Tobari Y.N., Tomimura Y., Tsolas J.M., Valente V.L.,
RA Venter E., Venter J.C., Vicario S., Vieira F.G., Vilella A.J.,
RA Villasante A., Walenz B., Wang J., Wasserman M., Watts T., Wilson D.,
RA Wilson R.K., Wing R.A., Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G.,
RA Yamamoto D., Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E.,
RA Zhang P., Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA Bayul T., Berlin A., Bessette D., Bloom T., Blye J., Boguslavskiy L.,
RA Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA Chin C., Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004370}.
CC Secreted, extracellular space, extracellular matrix, basement membrane
CC {ECO:0000256|ARBA:ARBA00004302}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00460}.
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DR EMBL; CH479202; EDW30062.1; -; Genomic_DNA.
DR RefSeq; XP_002024614.1; XM_002024578.1.
DR STRING; 7234.B4H185; -.
DR EnsemblMetazoa; FBtr0188143; FBpp0186635; FBgn0160120.
DR GeneID; 6599465; -.
DR KEGG; dpe:6599465; -.
DR eggNOG; KOG1836; Eukaryota.
DR HOGENOM; CLU_000301_1_0_1; -.
DR OMA; GECKCLT; -.
DR OrthoDB; 90222at2759; -.
DR PhylomeDB; B4H185; -.
DR Proteomes; UP000008744; Unassembled WGS sequence.
DR GO; GO:0005604; C:basement membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0036062; C:presynaptic periactive zone; IEA:EnsemblMetazoa.
DR GO; GO:0005102; F:signaling receptor binding; IEA:InterPro.
DR GO; GO:0007411; P:axon guidance; IEA:EnsemblMetazoa.
DR GO; GO:0071711; P:basement membrane organization; IEA:EnsemblMetazoa.
DR GO; GO:0033627; P:cell adhesion mediated by integrin; IEA:EnsemblMetazoa.
DR GO; GO:0035001; P:dorsal trunk growth, open tracheal system; IEA:EnsemblMetazoa.
DR GO; GO:0007507; P:heart development; IEA:EnsemblMetazoa.
DR GO; GO:0035011; P:melanotic encapsulation of foreign target; IEA:EnsemblMetazoa.
DR GO; GO:0007498; P:mesoderm development; IEA:EnsemblMetazoa.
DR GO; GO:0045886; P:negative regulation of synaptic assembly at neuromuscular junction; IEA:EnsemblMetazoa.
DR GO; GO:0030155; P:regulation of cell adhesion; IEA:InterPro.
DR GO; GO:0030334; P:regulation of cell migration; IEA:InterPro.
DR GO; GO:0045995; P:regulation of embryonic development; IEA:InterPro.
DR GO; GO:0034446; P:substrate adhesion-dependent cell spreading; IEA:EnsemblMetazoa.
DR CDD; cd02795; CBM6-CBM35-CBM36_like; 1.
DR CDD; cd00055; EGF_Lam; 21.
DR CDD; cd00110; LamG; 5.
DR Gene3D; 2.60.120.200; -; 5.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR Gene3D; 2.10.25.10; Laminin; 21.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR009254; Laminin_aI.
DR InterPro; IPR010307; Laminin_dom_II.
DR InterPro; IPR001791; Laminin_G.
DR InterPro; IPR000034; Laminin_IV.
DR InterPro; IPR008211; Laminin_N.
DR InterPro; IPR002049; LE_dom.
DR PANTHER; PTHR10574:SF435; LAMININ SUBUNIT GAMMA-1; 1.
DR PANTHER; PTHR10574; NETRIN/LAMININ-RELATED; 1.
DR Pfam; PF00052; Laminin_B; 1.
DR Pfam; PF00053; Laminin_EGF; 21.
DR Pfam; PF02210; Laminin_G_2; 5.
DR Pfam; PF06008; Laminin_I; 1.
DR Pfam; PF06009; Laminin_II; 1.
DR Pfam; PF00055; Laminin_N; 1.
DR PRINTS; PR00011; EGFLAMININ.
DR SMART; SM00181; EGF; 11.
DR SMART; SM00180; EGF_Lam; 22.
DR SMART; SM01411; Ephrin_rec_like; 4.
DR SMART; SM00281; LamB; 1.
DR SMART; SM00282; LamG; 5.
DR SMART; SM00136; LamNT; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 5.
DR SUPFAM; SSF57196; EGF/Laminin; 19.
DR PROSITE; PS00022; EGF_1; 2.
DR PROSITE; PS01248; EGF_LAM_1; 7.
DR PROSITE; PS50027; EGF_LAM_2; 15.
DR PROSITE; PS50025; LAM_G_DOMAIN; 5.
DR PROSITE; PS51115; LAMININ_IVA; 1.
DR PROSITE; PS51117; LAMININ_NTER; 1.
PE 4: Predicted;
KW Basement membrane {ECO:0000256|ARBA:ARBA00022869};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00460}; Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Laminin EGF-like domain {ECO:0000256|ARBA:ARBA00023292,
KW ECO:0000256|PROSITE-ProRule:PRU00460};
KW Reference proteome {ECO:0000313|Proteomes:UP000008744};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022530};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..3708
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002804622"
FT DOMAIN 20..272
FT /note="Laminin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51117"
FT DOMAIN 448..494
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 495..540
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 541..586
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 587..631
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 632..681
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 732..784
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 1375..1420
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 1421..1465
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 1466..1513
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 1514..1564
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 1592..1777
FT /note="Laminin IV type A"
FT /evidence="ECO:0000259|PROSITE:PS51115"
FT DOMAIN 1811..1918
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 1919..1971
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 1972..2018
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 2019..2065
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 2066..2113
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 2674..2871
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 2879..3050
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 3055..3225
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 3340..3519
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 3530..3705
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT REGION 3244..3289
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 2222..2249
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2381..2443
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2600..2676
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 3258..3289
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 448..460
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 470..479
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 495..507
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 497..514
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 516..525
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 541..553
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 543..560
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 562..571
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 587..599
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 607..616
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 632..644
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 652..661
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 755..764
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1375..1387
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1377..1394
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1396..1405
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1438..1447
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1489..1498
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1514..1526
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1516..1533
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1535..1544
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1889..1898
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1943..1952
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1955..1969
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1991..2000
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 2039..2048
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 2066..2078
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 2068..2085
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 2087..2096
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 3198..3225
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00122"
FT DISULFID 3678..3705
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00122"
SQ SEQUENCE 3708 AA; 411222 MW; 1068ADC709A03282 CRC64;
MGLPVPVGVA LCLLLAIAQC QAELTPPYFN LATGRKIFAT ATCGEDTDGP ELYCKLVGAN
TENDHIDYSV IQGQVCDVCD PNVPDKNHPP ENAIDGTEAW WQSPPLSRGM KYNEVDLTIN
FEQEFHVAYL FIRMGNSPRP GLWTLEKSVD YGKTWTPWQH FSDTPADCET YFGKDTYKPI
SRDDDVICTT EYSKIVPLEN GEIPVMLLNE RPSSTNYFNS SVLQEWTRAT NVRIRLLRTK
NLLGHLMSVA RQDPTVTRRY FYSIKDISIG GRCMCNGHAD TCDVKDPKSA VRILACRCQH
HTCGIQCNEC CPGFEQKKWR QNTNARPFNC EPCNCHGHST ECKYDEDVNR KGLSLDIHGH
YDGGGVCQNC QHNTVGINCN KCKPKYYRPK GKHWNDTDVC SPCQCDFFYS TGHCEEETGN
CECRAAFQPP NCDSCAYGYY GYPNCRECEC NLNGTNGYHC EAESGQQCPC KINFAGSYCK
QCAEGYYGFP ECKACECNQI GSITNDCNVT TGECKCLTNF GGDNCERCKH GYYNYPACSY
CDCDNQGTES EICNKQSGQC ICREGFGGPR CDQCLPGFYN YPDCKPCNCS STGSSAITCD
NTGKCNCLNN FAGKQCTLCS AGYYSYPDCL PCHCDSHGSQ GVTCNADGQC LCQPNFDGRQ
CDSCKESFYN FPRCDDCNCD PAGVIDKFSG CGSVPVGELC KCKERVYGHI CDECNHLYWN
LNISNPDGCE NCDCWTDGTI SGLDTCASKS GQCPCKPHTQ GRRCKECRDG TFDLDSSSLF
GCKDCQCDVG GSWASVCDKT SGQCKCHPRV TGRACTQPLT THYFPTLHQF QYEYEDGALP
SGTQVRYDYD EQKFPGFSSK GYVVFNTIQN EVRNELTVFK SSLYRIVLRY VNPNDENVTA
TILIQSDNPQ EVDQNVKVLL QPTKQPQFVT VSGPKGLKPS AIVLDPGPRY VFTTKASKNV
MLDYFVLLPA AYYEASILTR QISNPCELGN MELCRHYKYA SVEVFEPASV PFLIGSNGKA
AKPAEVYSDP EHLQIVSHVG DVPVLSRSQP ELNYIVDVPH SGRYIFVIDY ISHRNFTNTY
YVNLRLKNDP DSETSVLLYP CLYSTVCRTS VNDDGLEKSF YISKEDLQPV TIYADISDEY
RVPIISVTAI PVEQWSIDYI NPSPVCVIHN QQCSTPKFVS VPDSKKIEFE TDHEDRIATN
KPPYAVLDER VKLVHLDSNQ EGTIVIDSKV AEPDRYVILV KYYQPDNPKY QVYFTLTAAK
NQYDGHFDIQ HCPSSSGCRG VIRPGGEYDW FDIDDEFHFT ITNDRPQGVW LDYLVVVPLK
QYNEDLLVEE TFDQTKEFIK NCGHDDFHIT HNASEFCKKA VFSVTADYNS GALACNCDYA
GSTSFECRPF GGQCQCKPNV IERQCGTCRS RYYGFPDCKP CECPTSAMCE PTTGECMCPP
NVIGDLCEKC APNTYGFHQV IGCEECNCNY LGIANGNTQC DMFNGTCECR DNIEGRACDV
CAHGYYQFPR CDQCSCHTPG TELEVCDKID GSCFCKKNVV GRDCDQCVDG TYNLQDSNPD
GCTTCFCFGK TSRCDSAYLR VYNVSLLRQV SISTAEFNHN NKTIEFELWA VTPEELQLNE
TTLQADFTSR EVSDERPAYF GVLDYLLNQN SHISSYGGDL AYTLHFTSGF DGKSIVAPDV
ILMGKDKVLV HQSYEQPSRN MPFTNRLQMV ESNFQTHAGK TVSRADFMMV LRDLKAIYIR
ANYWEQTLVT HISDVYLSLA DEDADGTAEY QFLAVERCSC PPGYVGHSCE DCAPGYYRDP
NGPYGGYCIP CECNGHSETC DCATGICTGC QHGTQGEHCE DCVSGYYGNA TNGTPIDCMI
CACPLPFDSN NFATSCEISE SGNEIHCECR PGYTGPRCES CANGFYGNPE NVGDVCKPCD
CSGNINPEDQ GSCDTRTGEC LRCLNNTFGA ACNLCAPGFY GDAVKLKNCQ SCDCDDLGTL
ECDPFVGKCT CHENVIGERC DRCKADHYGF ESGLGCRACD CGAASNSTQC DAHTGHCACK
PGVTGRQCDR CAVDHWKYQK EGCTPCNCNQ GYSRGFGCNP NTGKCQCLPG VIGDRCDACP
NRWVLIKDEG CQECNNCHHA LLDVTDKMRY QIDSVLADFG SVTLAFFTSQ KLNYYDSLAD
ELAPKIKALD PTSVDLNPSK KSNSDLEADA KSYAKQVNQT LANALDIRDR SSSTLGNITS
AYDEALKSAD QAREAIAAVE ALSKNLETAA STKIDAALEQ AQHILGQIND TQIQLVANEQ
VLEKSRLLYD EVDALVQPIK EQNRSLNALK NDIGEFSDKL EDLFNWSDQS ETQSAEVERL
NVVNKQSFDN SKFATVSEQQ QEAETNIQDA GNYLINGDLT LNQIGQKLDN LRDALEELKS
VNKNVDEDLP LRDEQHQEAE QLTAQAEMRA AELAIKAQDL AEQYTDMTAH AEPAIKAATA
YSGIVEAVDA GQQFSQDAIT AAGNATQITD GIEERAGQAY SESADLLQKA RQSLQKVQDD
LEPRLNSSGG KVQQISQRNN ATEQQLKDIN ILIAQLPAAA QRDMWKSSNA NASDALEILK
NVLEILEPVS AQTPKELEKA HNINRDLDLT NKDISQANNQ LDNVEGSVSK LVELAEDVED
QQQRVATQTL QLGQDIENLK RQVETARQMA NNIKVGVKFR PSTVLELKTP EKAKLLATRT
NLSTFFRTNE KSGFLFFLGN DNATAQKNKD FVAVEIVNGY PILTIDLGNG PQRITNDKYV
SDGKWYQAVV DRVGSVAKLT IREQLPNGEV VEHQSDPKQL EGSQNILHVD RNSRLFVGGY
PAAPDFAAPE DITANYFNGD IEDLRIGDEN VGLWNFVYGE DNAEGVRERD VLLEKKKPVT
GLRFKGKGFV QLNATYNFKS RSTIKFNFKA DKDSSNGLLF FYGRDKHYMS IELVDGAVFF
NIKLGNGGVS SGSSNRYNDN KWHTVEAGRD GRTGLLKVDD ILLFHETAPA EADEELPKLR
RMYFGGYPRR FNNSEIVRQN FDGCIDDVII SGIVVDLTEY VNGTGVEEGC PERFSTVLSF
APNEYGFLRS HNISSDNNLH LNLRFKTLQP KGILFYATNN DQSSAIGLTL DDGYLKLRSQ
GSELVIDQRP FNDGEDHVVT VQHNAGELRL SVDDEEEERL GSPEPLQIEA GDIFFGGLPD
NYQTPRGALS TLAYFVGCIS DVTVNDEIIN FANSAEKKNG NINGCPPDIL AYEPDLLPNY
YPSGANELEP PSPGRITTHK PLATSAPTTT STTTTTTTTT TTTPATITST TVRPTPAEAA
EIVPQKTLTT RPTPKMNQPS DKRCKLPVEP NYDVDFETAG YRFYSLREQR LEINSLPVKL
KSHHDVSISF RTEHPNGLLF YASSKQKDDF VAVYLLDGRV TYQLRVGAGL TANITSEAEL
NDGKWHTVEI VRTAPRVSLI IDQTMQPGSV EVSQERSPPV FSVEMPIFVG GITKFVESEL
RRHTYFGGNT SYFNGCLTDI KFDGVALETE PTKYSVVPCS EQVERGVFFH SSSNQTTPPY
VKLFERFTVG AEMAISFDFR PREPNGLVFS VHGKNSYAIL ELVDNELFFT VKSDAKSTLV
TNFTLPANES FCDGKTRHVQ AIKSKFVINI AVDFVSSNPA VGNESSALTK TNRPLFMGGH
HAFQKAPGIK TKKTFKGCIS NVEINKKAIR ITPNMIAGDI WQGHCPLN
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