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Database: UniProt
Entry: B4HXK7_DROSE
LinkDB: B4HXK7_DROSE
Original site: B4HXK7_DROSE 
ID   B4HXK7_DROSE            Unreviewed;      1263 AA.
AC   B4HXK7;
DT   23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT   23-SEP-2008, sequence version 1.
DT   08-JUN-2016, entry version 52.
DE   SubName: Full=GM14610 {ECO:0000313|EMBL:EDW51787.1};
GN   Name=Dsec\GM14610 {ECO:0000313|EMBL:EDW51787.1};
GN   ORFNames=Dsec_GM14610 {ECO:0000313|EMBL:EDW51787.1}, GM14610
GN   {ECO:0000313|FlyBase:FBgn0169531};
OS   Drosophila sechellia (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;
OC   Ephydroidea; Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7238 {ECO:0000313|Proteomes:UP000001292};
RN   [1] {ECO:0000313|EMBL:EDW51787.1, ECO:0000313|Proteomes:UP000001292}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Rob3c / Tucson 14021-0248.25
RC   {ECO:0000313|Proteomes:UP000001292};
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 Genomes Consortium;
RA   Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B.,
RA   Markow T.A., Kaufman T.C., Kellis M., Gelbart W., Iyer V.N.,
RA   Pollard D.A., Sackton T.B., Larracuente A.M., Singh N.D., Abad J.P.,
RA   Abt D.N., Adryan B., Aguade M., Akashi H., Anderson W.W.,
RA   Aquadro C.F., Ardell D.H., Arguello R., Artieri C.G., Barbash D.A.,
RA   Barker D., Barsanti P., Batterham P., Batzoglou S., Begun D.,
RA   Bhutkar A., Blanco E., Bosak S.A., Bradley R.K., Brand A.D.,
RA   Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA   Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA   Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA   Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A.,
RA   Daub J., David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H.,
RA   Edwards K., Eickbush T., Evans J.D., Filipski A., Findeiss S.,
RA   Freyhult E., Fulton L., Fulton R., Garcia A.C., Gardiner A.,
RA   Garfield D.A., Garvin B.E., Gibson G., Gilbert D., Gnerre S.,
RA   Godfrey J., Good R., Gotea V., Gravely B., Greenberg A.J.,
RA   Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A., Haerty W.,
RA   Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA   Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A.,
RA   Hubisz M.J., Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S.,
RA   Jeck W.R., Johnson J., Jones C.D., Jordan W.C., Karpen G.H.,
RA   Kataoka E., Keightley P.D., Kheradpour P., Kirkness E.F.,
RA   Koerich L.B., Kristiansen K., Kudrna D., Kulathinal R.J., Kumar S.,
RA   Kwok R., Lander E., Langley C.H., Lapoint R., Lazzaro B.P., Lee S.J.,
RA   Levesque L., Li R., Lin C.F., Lin M.F., Lindblad-Toh K., Llopart A.,
RA   Long M., Low L., Lozovsky E., Lu J., Luo M., Machado C.A.,
RA   Makalowski W., Marzo M., Matsuda M., Matzkin L., McAllister B.,
RA   McBride C.S., McKernan B., McKernan K., Mendez-Lago M., Minx P.,
RA   Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E., Negre B.,
RA   Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA   Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S.,
RA   Pesole G., Phillippy A.M., Ponting C.P., Pop M., Porcelli D.,
RA   Powell J.R., Prohaska S., Pruitt K., Puig M., Quesneville H.,
RA   Ram K.R., Rand D., Rasmussen M.D., Reed L.K., Reenan R., Reily A.,
RA   Remington K.A., Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H.,
RA   Rohde C., Rozas J., Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L.,
RA   Sanchez-Gracia A., Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C.,
RA   Schlenke T., Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M.,
RA   Sisneros N.B., Smith C.D., Smith T.F., Spieth J., Stage D.E.,
RA   Stark A., Stephan W., Strausberg R.L., Strempel S., Sturgill D.,
RA   Sutton G., Sutton G.G., Tao W., Teichmann S., Tobari Y.N.,
RA   Tomimura Y., Tsolas J.M., Valente V.L., Venter E., Venter J.C.,
RA   Vicario S., Vieira F.G., Vilella A.J., Villasante A., Walenz B.,
RA   Wang J., Wasserman M., Watts T., Wilson D., Wilson R.K., Wing R.A.,
RA   Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G., Yamamoto D.,
RA   Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E., Zhang P.,
RA   Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA   Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A.,
RA   An P., Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P.,
RA   Barry A., Bayul T., Berlin A., Bessette D., Bloom T., Blye J.,
RA   Boguslavskiy L., Bonnet C., Boukhgalter B., Bourzgui I., Brown A.,
RA   Cahill P., Channer S., Cheshatsang Y., Chuda L., Citroen M.,
RA   Collymore A., Cooke P., Costello M., D'Aco K., Daza R., De Haan G.,
RA   DeGray S., DeMaso C., Dhargay N., Dooley K., Dooley E., Doricent M.,
RA   Dorje P., Dorjee K., Dupes A., Elong R., Falk J., Farina A., Faro S.,
RA   Ferguson D., Fisher S., Foley C.D., Franke A., Friedrich D.,
RA   Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA   Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA   Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA   Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA   Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F.,
RA   LeVine R., Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T.,
RA   Lokyitsang Y., Lubonja R., Lui A., MacDonald P., Magnisalis V.,
RA   Maru K., Matthews C., McCusker W., McDonough S., Mehta T., Meldrim J.,
RA   Meneus L., Mihai O., Mihalev A., Mihova T., Mittelman R., Mlenga V.,
RA   Montmayeur A., Mulrain L., Navidi A., Naylor J., Negash T., Nguyen T.,
RA   Nguyen N., Nicol R., Norbu C., Norbu N., Novod N., O'Neill B.,
RA   Osman S., Markiewicz E., Oyono O.L., Patti C., Phunkhang P.,
RA   Pierre F., Priest M., Raghuraman S., Rege F., Reyes R., Rise C.,
RA   Rogov P., Ross K., Ryan E., Settipalli S., Shea T., Sherpa N., Shi L.,
RA   Shih D., Sparrow T., Spaulding J., Stalker J., Stange-Thomann N.,
RA   Stavropoulos S., Stone C., Strader C., Tesfaye S., Thomson T.,
RA   Thoulutsang Y., Thoulutsang D., Topham K., Topping I., Tsamla T.,
RA   Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M., Wilkinson J.,
RA   Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D., Zimmer A.,
RA   Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J., Chin C.,
RA   Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
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DR   EMBL; CH480818; EDW51787.1; -; Genomic_DNA.
DR   RefSeq; XP_002035864.1; XM_002035828.1.
DR   ProteinModelPortal; B4HXK7; -.
DR   EnsemblMetazoa; FBtr0197595; FBpp0196087; FBgn0169531.
DR   GeneID; 6611317; -.
DR   KEGG; dse:Dsec_GM14610; -.
DR   FlyBase; FBgn0169531; Dsec\GM14610.
DR   KO; K17233; -.
DR   OMA; ASKWSPN; -.
DR   OrthoDB; EOG7GQXV3; -.
DR   PhylomeDB; B4HXK7; -.
DR   Proteomes; UP000001292; Unassembled WGS sequence.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:InterPro.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:InterPro.
DR   Gene3D; 2.60.40.10; -; 5.
DR   InterPro; IPR013162; CD80_C2-set.
DR   InterPro; IPR018469; Dual_oxidase_maturation_fac.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR003598; Ig_sub2.
DR   InterPro; IPR013106; Ig_V-set.
DR   Pfam; PF08205; C2-set_2; 1.
DR   Pfam; PF10204; DuoxA; 1.
DR   Pfam; PF07686; V-set; 1.
DR   SMART; SM00409; IG; 5.
DR   SMART; SM00408; IGc2; 5.
DR   SUPFAM; SSF48726; SSF48726; 5.
DR   PROSITE; PS50835; IG_LIKE; 5.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000001292};
KW   Disulfide bond {ECO:0000256|SAAS:SAAS00504776};
KW   Immunoglobulin domain {ECO:0000256|SAAS:SAAS00441151};
KW   Membrane {ECO:0000256|SAAS:SAAS00555457, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001292};
KW   Repeat {ECO:0000256|SAAS:SAAS00441186};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00555511,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00555568,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     29     50       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     57     75       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    186    208       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    214    234       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    255    281       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1091   1116       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      449    571       Ig-like (immunoglobulin-like).
FT                                {ECO:0000259|PROSITE:PS50835}.
FT   DOMAIN      576    675       Ig-like (immunoglobulin-like).
FT                                {ECO:0000259|PROSITE:PS50835}.
FT   DOMAIN      682    759       Ig-like (immunoglobulin-like).
FT                                {ECO:0000259|PROSITE:PS50835}.
FT   DOMAIN      778    865       Ig-like (immunoglobulin-like).
FT                                {ECO:0000259|PROSITE:PS50835}.
FT   DOMAIN      869    956       Ig-like (immunoglobulin-like).
FT                                {ECO:0000259|PROSITE:PS50835}.
SQ   SEQUENCE   1263 AA;  139912 MW;  AADC2A9957AB0B31 CRC64;
     MKGWFDAFRD DGGPTLYSFS NRTPVTGDVS IVAVSVLFAT FYVAFLVIFP GVRKQKFTTF
     STVTLSLFVG LVILITRLGS AWHVAHATII APYKAFSREK LPARIGTHIG LMHVNVTLTA
     IPIGNWTPPD IDYNERFTWE GANDMSANYR HALQRGLPFP ILTVAEYFSL GREGFSWGGQ
     YRAAGYFASI MLWASLASWL LMNLLLIAVP RYGAYMKALT GALLVCTTVG YHCLLPKRPL
     SIHLEGGRLE FHFGWCYWLV LVAGILCFIA GVLISIIDLV WPHTFSTVLE VYYGTPYDRH
     VILEESSDVR YRKPRNSRSL EDPPGLGSRI LRRLSSRHVI CNLARHRVAI VLPECPAAVV
     WKTRASSRMH QRVLGDIPSE GRSNWRSSST RIHCISIRCS STISTTSTTI SSSCSSWAVR
     WCSIPCIICS APCRRILDPA LLRQPCKSPR CTSTLWRGCC LKTKDIDSVE GKSVSLPCPI
     TEPLDNVYMV LWFRDNAGIP LYSFDVRDKE SREQPRHWSA PEVFGSRAKF HFDSQPATLE
     IKDIKRHDQG IYRCRVDFRT SQTQSFRFNL SVIILPEQPI ILDRWGRQLN GTQLGPKQEG
     DDIVITCRVV GGRPQPQVRW LVNGLLVDNQ NEHNSGDVIE NRLLWPSVQR NDLNSVFTCQ
     ALNTQLDKPK EKSFILDMHL KPLVVKILEP PSSMIADRRY EVSCESSGSR PNAIITWYKG
     KRQLRRTKDD ISKNSTRSEL SFVPTTDDDG KSITCRAENP NVNGLYLETM WKLNVVYPPL
     VTLRLGSTLT PDDIKEGDDV YFECHVQSNP QWRKLLWLHN GIHLEHNTSA RVIRSNQSLV
     LQKITKHYAG NYACSAINDE GETVSNQLPL RVKYTPMCKH ADRVILIGAS KDETVEVVCE
     IQADPPPRTF RWKFNNSGET LDVGSERFSV NGSRSILKYT PVTDQDYGTL SCWASNEVGT
     QQHPCLFQVV LAALPNAVSN CTVFNRTELS VDIQCIPGYD GGLPQIFVLE MFSTRTGITR
     FNLSNAEEAL FSLENLDTLT SMMVQENNSL RLRIYSYNQK GRSAAYLLPD FIIGSTAYKT
     DDDVTLTLSP VIVGSVLTII IIGVAIAIRI FVVTFVHNLR RNRHHGSKAT AAGVTAQPSD
     VFKGGNLEKP RWQHTDIKTK SSEDLVEDER DPDVIPSQYV GGSSAGSSGS NASNVGSTTA
     GTATGSSTST AVVANANAAA SAMSGPGGAT SSASATDGHQ CASATAAAGG GASKWSPNGN
     VST
//
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