ID B4I8A0_DROSE Unreviewed; 1219 AA.
AC B4I8A0;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 24-JAN-2024, entry version 60.
DE SubName: Full=GM15944 {ECO:0000313|EMBL:EDW56825.1};
GN Name=Dsec\GM15944 {ECO:0000313|EMBL:EDW56825.1};
GN ORFNames=Dsec_GM15944 {ECO:0000313|EMBL:EDW56825.1};
OS Drosophila sechellia (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7238 {ECO:0000313|Proteomes:UP000001292};
RN [1] {ECO:0000313|EMBL:EDW56825.1, ECO:0000313|Proteomes:UP000001292}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Rob3c / Tucson 14021-0248.25
RC {ECO:0000313|Proteomes:UP000001292};
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RA Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B., Markow T.A.,
RA Kaufman T.C., Kellis M., Gelbart W., Iyer V.N., Pollard D.A., Sackton T.B.,
RA Larracuente A.M., Singh N.D., Abad J.P., Abt D.N., Adryan B., Aguade M.,
RA Akashi H., Anderson W.W., Aquadro C.F., Ardell D.H., Arguello R.,
RA Artieri C.G., Barbash D.A., Barker D., Barsanti P., Batterham P.,
RA Batzoglou S., Begun D., Bhutkar A., Blanco E., Bosak S.A., Bradley R.K.,
RA Brand A.D., Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A., Daub J.,
RA David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H., Edwards K.,
RA Eickbush T., Evans J.D., Filipski A., Findeiss S., Freyhult E., Fulton L.,
RA Fulton R., Garcia A.C., Gardiner A., Garfield D.A., Garvin B.E., Gibson G.,
RA Gilbert D., Gnerre S., Godfrey J., Good R., Gotea V., Gravely B.,
RA Greenberg A.J., Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A.,
RA Haerty W., Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A., Hubisz M.J.,
RA Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S., Jeck W.R.,
RA Johnson J., Jones C.D., Jordan W.C., Karpen G.H., Kataoka E.,
RA Keightley P.D., Kheradpour P., Kirkness E.F., Koerich L.B., Kristiansen K.,
RA Kudrna D., Kulathinal R.J., Kumar S., Kwok R., Lander E., Langley C.H.,
RA Lapoint R., Lazzaro B.P., Lee S.J., Levesque L., Li R., Lin C.F., Lin M.F.,
RA Lindblad-Toh K., Llopart A., Long M., Low L., Lozovsky E., Lu J., Luo M.,
RA Machado C.A., Makalowski W., Marzo M., Matsuda M., Matzkin L.,
RA McAllister B., McBride C.S., McKernan B., McKernan K., Mendez-Lago M.,
RA Minx P., Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E.,
RA Negre B., Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S., Pesole G.,
RA Phillippy A.M., Ponting C.P., Pop M., Porcelli D., Powell J.R.,
RA Prohaska S., Pruitt K., Puig M., Quesneville H., Ram K.R., Rand D.,
RA Rasmussen M.D., Reed L.K., Reenan R., Reily A., Remington K.A.,
RA Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H., Rohde C., Rozas J.,
RA Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L., Sanchez-Gracia A.,
RA Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C., Schlenke T.,
RA Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M., Sisneros N.B.,
RA Smith C.D., Smith T.F., Spieth J., Stage D.E., Stark A., Stephan W.,
RA Strausberg R.L., Strempel S., Sturgill D., Sutton G., Sutton G.G., Tao W.,
RA Teichmann S., Tobari Y.N., Tomimura Y., Tsolas J.M., Valente V.L.,
RA Venter E., Venter J.C., Vicario S., Vieira F.G., Vilella A.J.,
RA Villasante A., Walenz B., Wang J., Wasserman M., Watts T., Wilson D.,
RA Wilson R.K., Wing R.A., Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G.,
RA Yamamoto D., Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E.,
RA Zhang P., Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA Bayul T., Berlin A., Bessette D., Bloom T., Blye J., Boguslavskiy L.,
RA Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA Chin C., Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
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DR EMBL; CH480824; EDW56825.1; -; Genomic_DNA.
DR RefSeq; XP_002039960.1; XM_002039924.1.
DR AlphaFoldDB; B4I8A0; -.
DR SMR; B4I8A0; -.
DR STRING; 7238.B4I8A0; -.
DR EnsemblMetazoa; FBtr0198929; FBpp0197421; FBgn0170860.
DR HOGENOM; CLU_274326_0_0_1; -.
DR OMA; WFLIAVR; -.
DR PhylomeDB; B4I8A0; -.
DR Proteomes; UP000001292; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR038884; CFAP61.
DR InterPro; IPR032151; CFAP61_N.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR PANTHER; PTHR21178; CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 61; 1.
DR PANTHER; PTHR21178:SF8; CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 61; 1.
DR Pfam; PF16092; CFAP61_N; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001292}.
FT DOMAIN 5..266
FT /note="Cilia- and flagella-associated protein 61 N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF16092"
FT DOMAIN 935..1046
FT /note="FAD/NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF07992"
SQ SEQUENCE 1219 AA; 142312 MW; 72205471F0241732 CRC64;
MNQFQIRLAQ AGDQDGLNKL IRSPGVKWFG NIRPKFRGKD SLFHSYQTYR ILALCTESSA
LVAYAEFRNY PSIAALPTDC WLEWLSTRYC LSMSISWLNA LFFNFCIYKS EHSTVLVEII
KDVLYRESRV WFLIAVRSPY MPQPIHFVET FDDLEKISKV FYPLEYSMDK NNNTQSLYIV
DRAEDNDDII AMQEVENPEM REELGDFYIA EEVMGQNPKS MLVVAETINQ SEQSEMAIFL
WLSSDIDIMF YVRNYQMEQF GNLVKPADGR SFHYETMTVS SVQRRAEASM FTADALQDLD
AVTILGGLQR VDSGMSVASL GKMKVSSIGG TIVDTNVANE NKFYMRECLY SKFKYILEKL
HSTDYYLRHE QSVINFIYPA GTEPAGPAAM AAASNVFLLR CIVARQDFPL PRLFNAMVAI
FSAYPDRDYC MMLMSVKYRA SKSYLEVMQY FMPVASRPSS LSSLDDVFIT HRSTIFGEIS
LYKLEKEDVA HVHNLALGNL PSNTQTPNSS SSSFSYCSKV NEREELEHEL HVLDAIMKDV
LENEFSEFAV FTIRCGISTR SVRENTAIGF VIVREFHSHD KLFEHYHLPK QEFQLNRRRA
EIISLRLHPL FLVSAGLIFR DLARKTSFYD YYFIHSVDGY KYSNDLKKMM MVVEPKPIKK
VPVFTRLQAD HKKPRKKLNL PPPNFSRDNM IIYRHKLNPV KWFTNSQKLV IIGFSAVTKA
FLRQLVFQWN SKDHKNSENF TCLTRLQVTV ICRAGIVEAD YDSLFKCPYC TNSQGCYLSY
PNESCYVRDC CMRIDLRSWV HFVPGKVEKV DSAFKMLREK KFVKLDSCEI YYDKLLLMCD
RLFVLRCIDV PVYSRRPCNL VEINFRLNKF LLFYKVRALL EDMPRTYLVL VYGNNLHTYE
CIAFLIGHGV DCSRMVFVQP HRITGRDADM KEKCPYWDKN LQMIMDDILV EKGVNIFTDY
DFHHYNLHKS TDFIMEVIFQ HFPTQKQMTF ECDLFISFQE GHLHQRHKQW IENSGIELDG
NEILVNERYQ TNDPDVYAAG SFIKMRITPN YQYKFVSERE LARKILHHLG MVTDKNFEDR
FAEPMLFQAI LPLRYFITKV TMPRRYLLSQ LPVIVNCNLT TYKNKTFCRV GLSTRMMVDE
IVVVTKKECN LDFLLYFCGK HELLLNKLKS RYRANLIHCF LKFFQEPWTE LIMHDDFEEL
QAENKELLSP MAISALSVG
//
