ID B4IYK7_DROGR Unreviewed; 1769 AA.
AC B4IYK7;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=GH15749 {ECO:0000313|EMBL:EDV95517.1};
GN Name=Dgri\GH15749 {ECO:0000313|EMBL:EDV95517.1};
GN ORFNames=Dgri_GH15749 {ECO:0000313|EMBL:EDV95517.1};
OS Drosophila grimshawi (Hawaiian fruit fly) (Idiomyia grimshawi).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Hawaiian Drosophila.
OX NCBI_TaxID=7222 {ECO:0000313|Proteomes:UP000001070};
RN [1] {ECO:0000313|EMBL:EDV95517.1, ECO:0000313|Proteomes:UP000001070}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tucson 15287-2541.00 {ECO:0000313|Proteomes:UP000001070};
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RA Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B., Markow T.A.,
RA Kaufman T.C., Kellis M., Gelbart W., Iyer V.N., Pollard D.A., Sackton T.B.,
RA Larracuente A.M., Singh N.D., Abad J.P., Abt D.N., Adryan B., Aguade M.,
RA Akashi H., Anderson W.W., Aquadro C.F., Ardell D.H., Arguello R.,
RA Artieri C.G., Barbash D.A., Barker D., Barsanti P., Batterham P.,
RA Batzoglou S., Begun D., Bhutkar A., Blanco E., Bosak S.A., Bradley R.K.,
RA Brand A.D., Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A., Daub J.,
RA David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H., Edwards K.,
RA Eickbush T., Evans J.D., Filipski A., Findeiss S., Freyhult E., Fulton L.,
RA Fulton R., Garcia A.C., Gardiner A., Garfield D.A., Garvin B.E., Gibson G.,
RA Gilbert D., Gnerre S., Godfrey J., Good R., Gotea V., Gravely B.,
RA Greenberg A.J., Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A.,
RA Haerty W., Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A., Hubisz M.J.,
RA Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S., Jeck W.R.,
RA Johnson J., Jones C.D., Jordan W.C., Karpen G.H., Kataoka E.,
RA Keightley P.D., Kheradpour P., Kirkness E.F., Koerich L.B., Kristiansen K.,
RA Kudrna D., Kulathinal R.J., Kumar S., Kwok R., Lander E., Langley C.H.,
RA Lapoint R., Lazzaro B.P., Lee S.J., Levesque L., Li R., Lin C.F., Lin M.F.,
RA Lindblad-Toh K., Llopart A., Long M., Low L., Lozovsky E., Lu J., Luo M.,
RA Machado C.A., Makalowski W., Marzo M., Matsuda M., Matzkin L.,
RA McAllister B., McBride C.S., McKernan B., McKernan K., Mendez-Lago M.,
RA Minx P., Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E.,
RA Negre B., Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S., Pesole G.,
RA Phillippy A.M., Ponting C.P., Pop M., Porcelli D., Powell J.R.,
RA Prohaska S., Pruitt K., Puig M., Quesneville H., Ram K.R., Rand D.,
RA Rasmussen M.D., Reed L.K., Reenan R., Reily A., Remington K.A.,
RA Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H., Rohde C., Rozas J.,
RA Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L., Sanchez-Gracia A.,
RA Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C., Schlenke T.,
RA Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M., Sisneros N.B.,
RA Smith C.D., Smith T.F., Spieth J., Stage D.E., Stark A., Stephan W.,
RA Strausberg R.L., Strempel S., Sturgill D., Sutton G., Sutton G.G., Tao W.,
RA Teichmann S., Tobari Y.N., Tomimura Y., Tsolas J.M., Valente V.L.,
RA Venter E., Venter J.C., Vicario S., Vieira F.G., Vilella A.J.,
RA Villasante A., Walenz B., Wang J., Wasserman M., Watts T., Wilson D.,
RA Wilson R.K., Wing R.A., Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G.,
RA Yamamoto D., Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E.,
RA Zhang P., Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA Bayul T., Berlin A., Bessette D., Bloom T., Blye J., Boguslavskiy L.,
RA Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA Chin C., Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
CC -!- SIMILARITY: Belongs to the DIP2 family.
CC {ECO:0000256|ARBA:ARBA00007735}.
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DR EMBL; CH916366; EDV95517.1; -; Genomic_DNA.
DR RefSeq; XP_001983169.1; XM_001983133.1.
DR STRING; 7222.B4IYK7; -.
DR EnsemblMetazoa; FBtr0151163; FBpp0149655; FBgn0123220.
DR GeneID; 6556703; -.
DR KEGG; dgr:6556703; -.
DR eggNOG; KOG3628; Eukaryota.
DR HOGENOM; CLU_001345_0_0_1; -.
DR InParanoid; B4IYK7; -.
DR OMA; LVWTYWT; -.
DR OrthoDB; 3994129at2759; -.
DR PhylomeDB; B4IYK7; -.
DR Proteomes; UP000001070; Unassembled WGS sequence.
DR CDD; cd05905; Dip2; 2.
DR Gene3D; 3.30.300.30; -; 2.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 2.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR037337; Dip2-like_dom.
DR InterPro; IPR010506; DMAP1-bd.
DR PANTHER; PTHR22754:SF32; DISCO-INTERACTING PROTEIN 2; 1.
DR PANTHER; PTHR22754; DISCO-INTERACTING PROTEIN 2 DIP2 -RELATED; 1.
DR Pfam; PF00501; AMP-binding; 2.
DR Pfam; PF06464; DMAP_binding; 1.
DR SMART; SM01137; DMAP_binding; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 2.
DR PROSITE; PS51912; DMAP1_BIND; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001070}.
FT DOMAIN 13..121
FT /note="DMAP1-binding"
FT /evidence="ECO:0000259|PROSITE:PS51912"
FT REGION 58..84
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 105..196
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 208..338
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 428..447
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 154..172
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 173..187
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 220..234
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 282..296
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 297..315
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1769 AA; 193655 MW; 2DAA13C68CF8401F CRC64;
MSTASANFLG MELVSSLPTD IREKLAELDL ELSEGDITQK GYEKKRAKLL QPFLKKPEPN
DVEKVKNLPP PPYYNIKDSN NSNSNVNIDG VIISSEGYSY VTEVPSLPSS QQRHSKKSDF
HQPASSSTPQ SGAGAPGYEN MRPQGGAVGD PGYQNTREPN TFQNLAHHPP TNSSQHRQRR
TQRKVTHNEK RYHSEVRQEA VQQALAALKG RPKPSLPMPS KRSSVLNRSP GCNDDLDSST
DDESIPEELI SPDKEYNYPR DHISNSMLPP EPIIKPPIRE SSMGVQHHHL RHEVKQSQAS
AQKYPSSSSG SVAERRPPQN LPPLPTSDTS STDSPPIAYK RDTELTDKAY KHKHFNAPDI
TQFNNAHRIA DRVTRYVNVS QTELNETDAN GKWKVSAKIQ QLLNTLKRPK RRPLPEFYED
NDIELEIAAN PKDPNAPKPE GSTMTPVQGE QLSIPAGLPR TLECALQRYG MNSFKSSMAT
VLDPNGKITT TLTYGKLLSR AQKIAYALST KIFSKGPEQV TLKPGDRVAL VYPNNDPLSF
ITAWYGCMFR GLVPLPIELP LSSSDTPPQQ VGFLLSSCGI TVALTSEACL KGLPKSATGE
IAKLKGWPRL QWFVTEHLPK PPKDFNVGNL RIEETAAAYI EYTTDKEGSV MGITVSRAAM
INHCRALTMA CHYTEGETIV CVLDFKREVG LWHAVLTSIL NGMHVVFIPY ALMKLRPSSW
MQLITKHRAS CCLVKSRDLH WGLLATKDHK DISLASLRML LVADGANPWS LSSCDQFLNV
FQAKGLRSDA ICPCASSSEV FTVSLRRPGR SSTTGFSQSA TGRGVLSMAA LSHGVVRVDS
EDSLTSLTLQ DCGQVMPAAQ MVVVRSEGAP VLCKTDQVGE ICVTSGSTGA SYFGLDGMTN
STFKVQPLLE DPELPKDGGG TIVGNPKPIS EENYVRSGLL GFLGPGGLVF VCGSRDGLMT
VTGRKHNADD IIATVLAVEP MRFIYRGRIA VFSIKVLRDE RVCVIAEQRP DCSEEESFQW
MSRVLQAVDS IHQVGIYCLA LVPPNHLPKT PLGGIHLCEA RRRFLEGSLH PANVLMCPHT
CVTNLPKPRE LHQDTGVGPA SVMVGNLVQG NRLAVAHGRD VGMAEDGERK PQLITGVLRW
RANTSPDHVI FTLLNSKGAI AKTLTCSELH KRAEKIAALL QERGKIEPGD HVALIFPPGL
DLLCAFYGCL YLGAIPITIR PPHPQNLITT LPTVRMIVDV SKSGIVLSIQ PIIKLLKSRE
AASSIDPKTW PPILDIDDNP KRKLAGIATV LLDSSAYLDF SVSTCGRLSG VNITHRSLSS
LCASLKLACE LYPSRHVALC LDPYCGLGFV MWTLIGVYSG HHSILIAPYE VEANPSLWLS
TLSQHRVRDT FCSYGVIELC TKALSNSVPS LKQRNVDLRC VRTCVVVGEE RPRVTLTQQF
CKLFQGLGLN TRCVSTSFGC RVNPAICVQG ASSAESAQVY VDLRALRNNR VALVERGAPN
SLCLIESGKL LPGVKVIIAN PETKGHCGDS HLGEIWVQAP HNANGYFTIY GDETDYNDHF
NAKLVTGATS EMYARTGYLG FLRRTECSQA ASVLDETTPS VASRDSDTES LNSMNQLQLN
FSNTSLGGNS EHSLVGGAVN SNDQELHDAV YVVGALDEVI SLRGMNYHPI DIENSVLRCH
KKIAECAVFT WTNLLVVVVE LDGNESEALD LVPLVTNTVL EEHQLIVGVV VVVDPGVVPI
NSRGEKQRMH LRDGFLADQL DPIYVAYNM
//
