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Database: UniProt
Entry: B4JJ16_DROGR
LinkDB: B4JJ16_DROGR
Original site: B4JJ16_DROGR 
ID   B4JJ16_DROGR            Unreviewed;      2099 AA.
AC   B4JJ16;
DT   23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT   23-SEP-2008, sequence version 1.
DT   27-SEP-2017, entry version 65.
DE   SubName: Full=GH12930 {ECO:0000313|EMBL:EDW00557.1};
GN   Name=Dgri\GH12930 {ECO:0000313|EMBL:EDW00557.1};
GN   ORFNames=Dgri_GH12930 {ECO:0000313|EMBL:EDW00557.1}, GH12930
GN   {ECO:0000313|FlyBase:FBgn0120408};
OS   Drosophila grimshawi (Fruit fly) (Idiomyia grimshawi).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha;
OC   Ephydroidea; Drosophilidae; Drosophila; Hawaiian Drosophila.
OX   NCBI_TaxID=7222 {ECO:0000313|Proteomes:UP000001070};
RN   [1] {ECO:0000313|EMBL:EDW00557.1, ECO:0000313|Proteomes:UP000001070}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tucson 15287-2541.00 {ECO:0000313|Proteomes:UP000001070};
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 Genomes Consortium;
RA   Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B.,
RA   Markow T.A., Kaufman T.C., Kellis M., Gelbart W., Iyer V.N.,
RA   Pollard D.A., Sackton T.B., Larracuente A.M., Singh N.D., Abad J.P.,
RA   Abt D.N., Adryan B., Aguade M., Akashi H., Anderson W.W.,
RA   Aquadro C.F., Ardell D.H., Arguello R., Artieri C.G., Barbash D.A.,
RA   Barker D., Barsanti P., Batterham P., Batzoglou S., Begun D.,
RA   Bhutkar A., Blanco E., Bosak S.A., Bradley R.K., Brand A.D.,
RA   Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA   Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA   Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA   Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A.,
RA   Daub J., David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H.,
RA   Edwards K., Eickbush T., Evans J.D., Filipski A., Findeiss S.,
RA   Freyhult E., Fulton L., Fulton R., Garcia A.C., Gardiner A.,
RA   Garfield D.A., Garvin B.E., Gibson G., Gilbert D., Gnerre S.,
RA   Godfrey J., Good R., Gotea V., Gravely B., Greenberg A.J.,
RA   Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A., Haerty W.,
RA   Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA   Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A.,
RA   Hubisz M.J., Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S.,
RA   Jeck W.R., Johnson J., Jones C.D., Jordan W.C., Karpen G.H.,
RA   Kataoka E., Keightley P.D., Kheradpour P., Kirkness E.F.,
RA   Koerich L.B., Kristiansen K., Kudrna D., Kulathinal R.J., Kumar S.,
RA   Kwok R., Lander E., Langley C.H., Lapoint R., Lazzaro B.P., Lee S.J.,
RA   Levesque L., Li R., Lin C.F., Lin M.F., Lindblad-Toh K., Llopart A.,
RA   Long M., Low L., Lozovsky E., Lu J., Luo M., Machado C.A.,
RA   Makalowski W., Marzo M., Matsuda M., Matzkin L., McAllister B.,
RA   McBride C.S., McKernan B., McKernan K., Mendez-Lago M., Minx P.,
RA   Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E., Negre B.,
RA   Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA   Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S.,
RA   Pesole G., Phillippy A.M., Ponting C.P., Pop M., Porcelli D.,
RA   Powell J.R., Prohaska S., Pruitt K., Puig M., Quesneville H.,
RA   Ram K.R., Rand D., Rasmussen M.D., Reed L.K., Reenan R., Reily A.,
RA   Remington K.A., Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H.,
RA   Rohde C., Rozas J., Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L.,
RA   Sanchez-Gracia A., Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C.,
RA   Schlenke T., Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M.,
RA   Sisneros N.B., Smith C.D., Smith T.F., Spieth J., Stage D.E.,
RA   Stark A., Stephan W., Strausberg R.L., Strempel S., Sturgill D.,
RA   Sutton G., Sutton G.G., Tao W., Teichmann S., Tobari Y.N.,
RA   Tomimura Y., Tsolas J.M., Valente V.L., Venter E., Venter J.C.,
RA   Vicario S., Vieira F.G., Vilella A.J., Villasante A., Walenz B.,
RA   Wang J., Wasserman M., Watts T., Wilson D., Wilson R.K., Wing R.A.,
RA   Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G., Yamamoto D.,
RA   Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E., Zhang P.,
RA   Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA   Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A.,
RA   An P., Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P.,
RA   Barry A., Bayul T., Berlin A., Bessette D., Bloom T., Blye J.,
RA   Boguslavskiy L., Bonnet C., Boukhgalter B., Bourzgui I., Brown A.,
RA   Cahill P., Channer S., Cheshatsang Y., Chuda L., Citroen M.,
RA   Collymore A., Cooke P., Costello M., D'Aco K., Daza R., De Haan G.,
RA   DeGray S., DeMaso C., Dhargay N., Dooley K., Dooley E., Doricent M.,
RA   Dorje P., Dorjee K., Dupes A., Elong R., Falk J., Farina A., Faro S.,
RA   Ferguson D., Fisher S., Foley C.D., Franke A., Friedrich D.,
RA   Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA   Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA   Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA   Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA   Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F.,
RA   LeVine R., Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T.,
RA   Lokyitsang Y., Lubonja R., Lui A., MacDonald P., Magnisalis V.,
RA   Maru K., Matthews C., McCusker W., McDonough S., Mehta T., Meldrim J.,
RA   Meneus L., Mihai O., Mihalev A., Mihova T., Mittelman R., Mlenga V.,
RA   Montmayeur A., Mulrain L., Navidi A., Naylor J., Negash T., Nguyen T.,
RA   Nguyen N., Nicol R., Norbu C., Norbu N., Novod N., O'Neill B.,
RA   Osman S., Markiewicz E., Oyono O.L., Patti C., Phunkhang P.,
RA   Pierre F., Priest M., Raghuraman S., Rege F., Reyes R., Rise C.,
RA   Rogov P., Ross K., Ryan E., Settipalli S., Shea T., Sherpa N., Shi L.,
RA   Shih D., Sparrow T., Spaulding J., Stalker J., Stange-Thomann N.,
RA   Stavropoulos S., Stone C., Strader C., Tesfaye S., Thomson T.,
RA   Thoulutsang Y., Thoulutsang D., Topham K., Topping I., Tsamla T.,
RA   Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M., Wilkinson J.,
RA   Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D., Zimmer A.,
RA   Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J., Chin C.,
RA   Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
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DR   EMBL; CH916370; EDW00557.1; -; Genomic_DNA.
DR   RefSeq; XP_001991932.1; XM_001991896.1.
DR   STRING; 7222.FBpp0146836; -.
DR   EnsemblMetazoa; FBtr0148344; FBpp0146836; FBgn0120408.
DR   GeneID; 6564772; -.
DR   KEGG; dgr:Dgri_GH12930; -.
DR   FlyBase; FBgn0120408; Dgri\GH12930.
DR   eggNOG; KOG2301; Eukaryota.
DR   eggNOG; ENOG410XNP6; LUCA.
DR   InParanoid; B4JJ16; -.
DR   KO; K21863; -.
DR   OMA; MLGDSAM; -.
DR   OrthoDB; EOG091G00F9; -.
DR   PhylomeDB; B4JJ16; -.
DR   Proteomes; UP000001070; Unassembled WGS sequence.
DR   GO; GO:0043679; C:axon terminus; IEA:EnsemblMetazoa.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0043025; C:neuronal cell body; IEA:EnsemblMetazoa.
DR   GO; GO:0005261; F:cation channel activity; IEA:InterPro.
DR   GO; GO:0008344; P:adult locomotory behavior; IEA:EnsemblMetazoa.
DR   GO; GO:0045475; P:locomotor rhythm; IEA:EnsemblMetazoa.
DR   GO; GO:0042752; P:regulation of circadian rhythm; IEA:EnsemblMetazoa.
DR   GO; GO:0072347; P:response to anesthetic; IEA:EnsemblMetazoa.
DR   GO; GO:0050975; P:sensory perception of touch; IEA:EnsemblMetazoa.
DR   GO; GO:0035176; P:social behavior; IEA:EnsemblMetazoa.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR028823; NALCN.
DR   PANTHER; PTHR10037:SF252; PTHR10037:SF252; 1.
DR   Pfam; PF00520; Ion_trans; 4.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000001070};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001070};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    403    425       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    526    549       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    615    635       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    682    700       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    738    761       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    805    828       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1122   1146       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1166   1184       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1258   1277       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1374   1397       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1455   1474       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1480   1498       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1540   1556       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1576   1597       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1663   1685       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      265    559       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      611    832       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN     1128   1402       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN     1450   1696       Ion_trans. {ECO:0000259|Pfam:PF00520}.
SQ   SEQUENCE   2099 AA;  235911 MW;  6170F9B261BEC17E CRC64;
     MIDRLQIRRL GAAARNKRTG GGGGSFHSAS GITTPATAST SSSSGNSLTP QQHQHSLPSS
     HHPHQHSQHS HLRSSQQHSQ QQLSHFTFNP SPGSSPGNGL GTRQDASSAL NSPTTIVNSG
     SGSGGGSSTA YGMHPPAGGS SIAAAPPPTA TSTAASNAHN NGAGGPPCPV GGGLNLLGGI
     GGLGGGAASA GMGICGGISS TVGSAAITGV PPIGLGIATG IGNKIMLGRK QSLKGGEPFL
     ADYGPEESLN ESADIEWVNK LWVRRLMRLC ALVSLASVSL NTPKTFERHP SLQYITFVSD
     TAVTFLFTAE MIAKMHIRGV LNGEVPYLKD HWCQFDASMV SFLWVSIILQ IFEVLEIVPK
     FSYLSIMRAP RPLIMIRFLR VFLKFSMPKS RINQIFKRSS QQIYNVTLFF LFFMSLYGLL
     GVQFFGELKN HCVMNNTKYD ENGLPVLTIN SLAIPDTFCS MDPDSGYQCS PGMRCMKMDF
     LSSYVIGFNG FEDIATSIFT VYQAASQEGW VFIMYRAIDS LPAWRAAFYF STMIFFLAWL
     VKNVFIAVIT ETFNEIRVQF QQMWGARGHI QKTAASQILS GNDSGWRLVT IDDNKHGGLA
     PETCHAILRS PYFRMLVMTV ILANGIVTAT MAFKHDGRPR HVFYERYYYI EVVFTCLLDL
     ETLFKIYCLG WRGYYKHSIH KFELLLAAGT TLHIVPMFYL SGLTYFQVLR VVRLIKASPM
     LEGFVYKIFG PGKKLGSLII FTMCLLIISS SISMQLFCFL CDFTKFESFP EAFMSMFQIL
     TQEAWVEVMD ETMIRTSKTL TPLVAVYFIL YHLFVTLIVL SLFVAVILDN LELDEDIKKL
     KQLKFREQSA EIKETLPFRL RIFEKFPDSP QMTILHRIPN DFMLPKVRES FMKHFVIELE
     TDDPSLVENC KRPMSECWES NVVFRKQKPV RIMNKTAKVR AAGSSLRKLA ITHIINDSNN
     QRLMLGDSAM LPVVGTKGGL KSQGTITHSK PWRVDQKKFG SRSIRRSVRS GSIKLKQTYE
     HLMENGDIAA APRANSGRAR PHDLDIKLLQ AKRQQAEMRR NQREEDLREN HPFFDTPLFL
     VPRESRFRKI CQKIVHARYD ARLKDPLTGK ERKVQYKSLH NFLGLVTYLD WVMIFATTLS
     CISMMFETPN YRLMDHPTLQ IAEYGFVIFM SLELAMKILA DGLFFTPKAY IKDVAAALDV
     FIYVVSTSFL CWMPHNIPTN SAAQLLMILR CVRPLRIFTL VPHMRKVVYE LCRGFKEILL
     VSTLLILLMF IFASYGVQLY GGRLARCNDP TILRREDCVG VFMRRVFVTK MKLTPGPDES
     YPAMLVPRVW ANPRRFNFDN IGDAMLTLFE VLSFKGWLDV RDVLIKAVGP IHAIYIHIYI
     FLGCMIGLTL FVGVVIANYS ENKGTALLTV DQRRWCDLKK RLKIAQPLHL PPRPDGRKIR
     AFTYDITQHI IFKRVIAVVV LINSMLLSIT WIKGEVHTER LVIVSAVLTF VFVIEVVMKN
     IAFTPRGYWQ SRRNRYDLLV TVAGVIWIIL QTLLRNDLSY FFGFMVVILR FFTITGKHTT
     LKMLMLTVGV SVCKSFFIIF GMFLLVFFYA LAGTILFGTV KYGEGIGRRA NFGSPVTGVA
     MLFRIVTGED WNKIMHDCMV QPPYCTLGGN YWETDCGNFT ASLIYFCTFY VIITYIVLNL
     LVAIIMENFS LFYSNEEDAL LSYADIRNFQ NTWNIVDIHQ RGVIPVRRVK FILRLLKGRL
     ECDPQKDRLL FKYMCYELDK LHNGEDVTFH DVINMLSYRS VDIRKALQLE ELLAREEFEY
     LVEEEVAKMT IRTWLEGCLK KIRAQNASKQ QNSLIAGLRA TNEQLVMRPN VQEDKAPSGV
     IDKSAISTIS GAVAGTCPPT SDAFSPTFSS TENDEKDASS SAVVLPHTDS HTTAAGARHV
     MTVGKRAYAL NRSDSTGSSA GRKFLAPTSS DPQQRSTLSD KERLHISSQQ RKKNSMTTLP
     HAAQLGQLGQ MGKQREVNKS SSFFSQLNSE IGQFHYPTIN ATAAAAAAAL HNFGDHHHHH
     QHQHQHHHGA LTSPSAMISQ LIGGSGKLLP FNNQANAVYE VHDWWQEQVL CTQTSDDEV
//
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