ID B4KE14_DROMO Unreviewed; 1461 AA.
AC B4KE14;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 2.
DT 24-JAN-2024, entry version 70.
DE SubName: Full=Uncharacterized protein, isoform A {ECO:0000313|EMBL:EDW16035.2};
GN Name=Dmoj\GI10302 {ECO:0000313|EMBL:EDW16035.2};
GN ORFNames=Dmoj_GI10302 {ECO:0000313|EMBL:EDW16035.2};
OS Drosophila mojavensis (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila.
OX NCBI_TaxID=7230 {ECO:0000313|EMBL:EDW16035.2, ECO:0000313|Proteomes:UP000009192};
RN [1] {ECO:0000313|EMBL:EDW16035.2, ECO:0000313|Proteomes:UP000009192}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tucson 15081-1352.22 {ECO:0000313|Proteomes:UP000009192};
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RA Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B., Markow T.A.,
RA Kaufman T.C., Kellis M., Gelbart W., Iyer V.N., Pollard D.A., Sackton T.B.,
RA Larracuente A.M., Singh N.D., Abad J.P., Abt D.N., Adryan B., Aguade M.,
RA Akashi H., Anderson W.W., Aquadro C.F., Ardell D.H., Arguello R.,
RA Artieri C.G., Barbash D.A., Barker D., Barsanti P., Batterham P.,
RA Batzoglou S., Begun D., Bhutkar A., Blanco E., Bosak S.A., Bradley R.K.,
RA Brand A.D., Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A., Daub J.,
RA David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H., Edwards K.,
RA Eickbush T., Evans J.D., Filipski A., Findeiss S., Freyhult E., Fulton L.,
RA Fulton R., Garcia A.C., Gardiner A., Garfield D.A., Garvin B.E., Gibson G.,
RA Gilbert D., Gnerre S., Godfrey J., Good R., Gotea V., Gravely B.,
RA Greenberg A.J., Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A.,
RA Haerty W., Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A., Hubisz M.J.,
RA Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S., Jeck W.R.,
RA Johnson J., Jones C.D., Jordan W.C., Karpen G.H., Kataoka E.,
RA Keightley P.D., Kheradpour P., Kirkness E.F., Koerich L.B., Kristiansen K.,
RA Kudrna D., Kulathinal R.J., Kumar S., Kwok R., Lander E., Langley C.H.,
RA Lapoint R., Lazzaro B.P., Lee S.J., Levesque L., Li R., Lin C.F., Lin M.F.,
RA Lindblad-Toh K., Llopart A., Long M., Low L., Lozovsky E., Lu J., Luo M.,
RA Machado C.A., Makalowski W., Marzo M., Matsuda M., Matzkin L.,
RA McAllister B., McBride C.S., McKernan B., McKernan K., Mendez-Lago M.,
RA Minx P., Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E.,
RA Negre B., Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S., Pesole G.,
RA Phillippy A.M., Ponting C.P., Pop M., Porcelli D., Powell J.R.,
RA Prohaska S., Pruitt K., Puig M., Quesneville H., Ram K.R., Rand D.,
RA Rasmussen M.D., Reed L.K., Reenan R., Reily A., Remington K.A.,
RA Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H., Rohde C., Rozas J.,
RA Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L., Sanchez-Gracia A.,
RA Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C., Schlenke T.,
RA Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M., Sisneros N.B.,
RA Smith C.D., Smith T.F., Spieth J., Stage D.E., Stark A., Stephan W.,
RA Strausberg R.L., Strempel S., Sturgill D., Sutton G., Sutton G.G., Tao W.,
RA Teichmann S., Tobari Y.N., Tomimura Y., Tsolas J.M., Valente V.L.,
RA Venter E., Venter J.C., Vicario S., Vieira F.G., Vilella A.J.,
RA Villasante A., Walenz B., Wang J., Wasserman M., Watts T., Wilson D.,
RA Wilson R.K., Wing R.A., Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G.,
RA Yamamoto D., Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E.,
RA Zhang P., Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA Bayul T., Berlin A., Bessette D., Bloom T., Blye J., Boguslavskiy L.,
RA Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA Chin C., Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
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DR EMBL; CH933806; EDW16035.2; -; Genomic_DNA.
DR RefSeq; XP_002000574.2; XM_002000538.2.
DR SMR; B4KE14; -.
DR EnsemblMetazoa; FBtr0161027; FBpp0159519; FBgn0133067.
DR GeneID; 6574531; -.
DR KEGG; dmo:Dmoj_GI10302; -.
DR eggNOG; ENOG502RXR3; Eukaryota.
DR HOGENOM; CLU_253535_0_0_1; -.
DR InParanoid; B4KE14; -.
DR OrthoDB; 5400354at2759; -.
DR Proteomes; UP000009192; Unassembled WGS sequence.
DR GO; GO:0005794; C:Golgi apparatus; IEA:EnsemblMetazoa.
DR GO; GO:0031267; F:small GTPase binding; IEA:EnsemblMetazoa.
DR CDD; cd13309; PH_SKIP; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR46556; PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 2; 1.
DR PANTHER; PTHR46556:SF1; PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 2; 1.
DR Pfam; PF00169; PH; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000009192}.
FT DOMAIN 1128..1232
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 303..327
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 468..496
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 509..530
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 635..801
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1303..1340
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 654..735
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 759..781
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1461 AA; 161908 MW; 45688C809A7C7A0F CRC64;
MKSAEHKLSM EFSHQIEETL VETYAYDVVM ESPLYPKVNN NLSAKVSPGG GGDKMSLSMN
TSCSLEEDTT PSDSGVQMLD SENSDIMLES LCSQSGLEFE EPVKTQILPI SQPIDGNSNV
AAEDNMTASA CSTFDTAEKI VYRRKVHKTS STPKAPKKRV SFHEDILKNT RTDNIHIEHG
FITYKNGRKL AVMGGNSAGV AGAAGRYSWC AERDRVQAPS ELSAAGRDAG EREAGNGAVG
HNRRLVYRNA CSDVLDYGNT DIYDTNEPVG LQYDNSGVFE YGPSAADTNR RDDRLLYRCA
CSSSNSSLDS DEQDKNSNSN SNTNRKQYEQ AKSSSCDCIG MSNANNNLIG DNCYYSEPNI
GDAGSPKQKS VWNKEKKPKS SCLKKTKRHT NIIHEQDLNE RVKKFNVHDI KHQLLDNSSK
MIFGSLKSIF TMPLPERGVP EGSEDLQSVV ECVPELEQTP EHKPKVYAQC ESPDSPPVKA
KPFLSKSLDG TKQTQSVKKF VHNVDEQLRR KNDEQNSSAE ASPLEQQPHV LRRQDEFDNE
PVVAAPIVTS TQNEFRSKFI INCESTVFEH TGVSYETSEP QQETERQLST TQHNNVAGLL
ERDTPIAQPA SQLRSSFMGA PIAKTFSNFF RSLKENSSSS ATVDKELQQK RKVEEQQQQL
AATDSYFASK MSKTPQQSHQ PQQQQYQPLS TKMPTTQSSS TISELSSISN NTNSNSTSCT
KPQTPNTNNV HGLMLGNVDR QSRHLPSPLK KRSGQPPRYG EPPQQQQQSM HSRSLHSPSS
YLGSARGGAA VGGSGRDSKS TILSEEFDDI LTITTTTDTA NERPSTESDL VIVDYNDVDY
AQLLKPPVPP AKTSLINRFL RNVTQKKILE SSIRKNDFFA DKLRSEHKHL GSNLYVRGVR
PKNYELIDDL NAEIAMEIEM SGANSPRREL AVGMDLDLPG DVSRFELGIG EISIDIFNGK
HLPMLREPNE QLLKVFKLYT GYSREGFMTP VLVLLTDKTL YVTDLVRNCL CAKFVLAYKE
LDVILMGPFG NTVLLSNSMR DMQQVLLAGG PYPADALVAN LELCARRSGS TLPAVGQLTL
EHLAPLQAFV RANSCVSKDE RWMFYAVVNM PAGGALGRGL DGEQEPLGPH IKGFLMHRRV
RETATANAAA KISWQPGYFL LKAGVLYMFH DSTQKLPSWA MALAECQGAR RAVKSARPHC
FEIMLKGELL QMAAPDEYVA SEWLQALLQS ASGLFELQER HKALGCTLIV TQNHLITLRE
DFTAPLRQLN SQSETPPAAA EQKQLLRDEE MLCIFETSSL LSSTMSTPTR GTQQSCSSLN
STPTKQSVDT SKAVPKGQSH NMSSVYGKNS GLEILTCADI KAMTGIKIPS HSETWWCILE
FSCQEAPLEC LDDLVIFFAS SAEMQRFLRL LEQLWQAKNN DLFPITILDD DETIAEQCTM
LYLDINRAWE PLLSAALGYP L
//
