ID B4KQG5_DROMO Unreviewed; 1306 AA.
AC B4KQG5;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 24-JAN-2024, entry version 64.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EDW10305.1};
DE EC=3.-.-.- {ECO:0000313|EMBL:EDW10305.1};
GN Name=Dmoj\GI21005 {ECO:0000313|EMBL:EDW10305.1};
GN ORFNames=Dmoj_GI21005 {ECO:0000313|EMBL:EDW10305.1};
OS Drosophila mojavensis (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila.
OX NCBI_TaxID=7230 {ECO:0000313|EMBL:EDW10305.1, ECO:0000313|Proteomes:UP000009192};
RN [1] {ECO:0000313|EMBL:EDW10305.1, ECO:0000313|Proteomes:UP000009192}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tucson 15081-1352.22 {ECO:0000313|Proteomes:UP000009192};
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RA Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B., Markow T.A.,
RA Kaufman T.C., Kellis M., Gelbart W., Iyer V.N., Pollard D.A., Sackton T.B.,
RA Larracuente A.M., Singh N.D., Abad J.P., Abt D.N., Adryan B., Aguade M.,
RA Akashi H., Anderson W.W., Aquadro C.F., Ardell D.H., Arguello R.,
RA Artieri C.G., Barbash D.A., Barker D., Barsanti P., Batterham P.,
RA Batzoglou S., Begun D., Bhutkar A., Blanco E., Bosak S.A., Bradley R.K.,
RA Brand A.D., Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A., Daub J.,
RA David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H., Edwards K.,
RA Eickbush T., Evans J.D., Filipski A., Findeiss S., Freyhult E., Fulton L.,
RA Fulton R., Garcia A.C., Gardiner A., Garfield D.A., Garvin B.E., Gibson G.,
RA Gilbert D., Gnerre S., Godfrey J., Good R., Gotea V., Gravely B.,
RA Greenberg A.J., Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A.,
RA Haerty W., Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A., Hubisz M.J.,
RA Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S., Jeck W.R.,
RA Johnson J., Jones C.D., Jordan W.C., Karpen G.H., Kataoka E.,
RA Keightley P.D., Kheradpour P., Kirkness E.F., Koerich L.B., Kristiansen K.,
RA Kudrna D., Kulathinal R.J., Kumar S., Kwok R., Lander E., Langley C.H.,
RA Lapoint R., Lazzaro B.P., Lee S.J., Levesque L., Li R., Lin C.F., Lin M.F.,
RA Lindblad-Toh K., Llopart A., Long M., Low L., Lozovsky E., Lu J., Luo M.,
RA Machado C.A., Makalowski W., Marzo M., Matsuda M., Matzkin L.,
RA McAllister B., McBride C.S., McKernan B., McKernan K., Mendez-Lago M.,
RA Minx P., Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E.,
RA Negre B., Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S., Pesole G.,
RA Phillippy A.M., Ponting C.P., Pop M., Porcelli D., Powell J.R.,
RA Prohaska S., Pruitt K., Puig M., Quesneville H., Ram K.R., Rand D.,
RA Rasmussen M.D., Reed L.K., Reenan R., Reily A., Remington K.A.,
RA Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H., Rohde C., Rozas J.,
RA Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L., Sanchez-Gracia A.,
RA Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C., Schlenke T.,
RA Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M., Sisneros N.B.,
RA Smith C.D., Smith T.F., Spieth J., Stage D.E., Stark A., Stephan W.,
RA Strausberg R.L., Strempel S., Sturgill D., Sutton G., Sutton G.G., Tao W.,
RA Teichmann S., Tobari Y.N., Tomimura Y., Tsolas J.M., Valente V.L.,
RA Venter E., Venter J.C., Vicario S., Vieira F.G., Vilella A.J.,
RA Villasante A., Walenz B., Wang J., Wasserman M., Watts T., Wilson D.,
RA Wilson R.K., Wing R.A., Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G.,
RA Yamamoto D., Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E.,
RA Zhang P., Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA Bayul T., Berlin A., Bessette D., Bloom T., Blye J., Boguslavskiy L.,
RA Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA Chin C., Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
CC -!- SIMILARITY: Belongs to the oxoprolinase family.
CC {ECO:0000256|ARBA:ARBA00010403}.
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DR EMBL; CH933808; EDW10305.1; -; Genomic_DNA.
DR RefSeq; XP_002006370.1; XM_002006334.2.
DR EnsemblMetazoa; FBtr0171730; FBpp0170222; FBgn0143737.
DR GeneID; 6580539; -.
DR KEGG; dmo:Dmoj_GI21005; -.
DR eggNOG; KOG1939; Eukaryota.
DR HOGENOM; CLU_002157_0_1_1; -.
DR InParanoid; B4KQG5; -.
DR OMA; TDCNVML; -.
DR OrthoDB; 674at2759; -.
DR PhylomeDB; B4KQG5; -.
DR Proteomes; UP000009192; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR InterPro; IPR008040; Hydant_A_N.
DR InterPro; IPR002821; Hydantoinase_A.
DR InterPro; IPR003692; Hydantoinase_B.
DR InterPro; IPR045079; Oxoprolinase_fam.
DR PANTHER; PTHR11365:SF2; 5-OXOPROLINASE; 1.
DR PANTHER; PTHR11365; 5-OXOPROLINASE RELATED; 1.
DR Pfam; PF05378; Hydant_A_N; 1.
DR Pfam; PF01968; Hydantoinase_A; 1.
DR Pfam; PF02538; Hydantoinase_B; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:EDW10305.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000009192}.
FT DOMAIN 15..220
FT /note="Hydantoinase/oxoprolinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF05378"
FT DOMAIN 240..537
FT /note="Hydantoinase A/oxoprolinase"
FT /evidence="ECO:0000259|Pfam:PF01968"
FT DOMAIN 748..1269
FT /note="Hydantoinase B/oxoprolinase"
FT /evidence="ECO:0000259|Pfam:PF02538"
SQ SEQUENCE 1306 AA; 140936 MW; C304C8798AE93701 CRC64;
MVSSVSAEGN NKYCFAIDRG GTFTDVLCIC PGGRVRTMKL LSEDPERYSD APREGIRRIL
KEETGADLTA AGLVDTSKIG WVRMGTTVAT NALLERKGDP VVLVVNSGFR DLLYIGNQAR
PKIFDLNIRK PANLYQTVVE VDCRIVPEQA DRCQLNHQWK VLQGITGCRY LEVQPVDELT
VRASLTAARQ QGINSVAVVL AHSYACPEHE LRIGAIATEL GFNHVTLSHK AMPMCRVVAR
GYTACAEAYL TPHVDRYLAS FKSGFENQLA GVDVLFMQSD GGLTNMENFR GARAILSGPA
GGVVGYALTG SRETDLPLIG FDMGGTSTDV SRYAGTYEHV IESTTAGVTI QAPQLDINTV
AAGGGSRLFF RSGIFVVGPE SAGSHPGPAC YKKGGPLTVT DANLILGRIL PQYFPKIFGP
NENEPLDYEL TKRKFSELQS DINEHLKASG DSRVLSIEEV ALGFIRVANE TMCRPIRALT
QSRGLDTANH VLSCFGGAGG QHACSIARNL GIAKVVIHKY AGVLSAYGMA LADVVQEVQE
PCGAEFNNAN AQLIKDRLDA LSVQCRGQLA AQGFKQIELQ AFLHLRYEAT DGALMCTAAP
VEQSQLSDQS PSPLLSAYGD FHATFLERYR TEFGFVLQNR RIIVDDIRIR GLGKNETPPE
LQVEQAQEAS PTAEGLTEVH FDQGTFQTPI YLTKHLLAGH QISGPAVLID QLSTIIVEPE
CTVQVTTYGD LIMDVQTSGK HGINADLDPV HLSIFSHRFM SIAEQMGRVL QRTSISTNIK
ERLDFSCALF GPDGGLVSNA PHIPVHLGAM QETVQYQLRV RGDTLKNGDV ILANHPQAGG
SHLPDLTVIT PVFFKSEPRP VFFVASRGHH ADIGGITPGS MPPHSTSLAQ EGAAFKSFLI
VENGVFQEEK IIQRLTTPTG AKGAVGTRNL SDNLSDLKAQ IAANHKGIHL VSELISSYSL
NVVQAYMHHI QKNAELAVRD MLRQIGRDTL ERTGSTVLVA QEFMDDGSPI SLRVTIDPEN
GSALCDFSGS GEEVWGNCNA PRAITLSALI YCLRCMVGHD VPLNQGCLAP IQVVIPKNSI
LDPSEGAAVV GGNVQTSQRI VDTVLKAFRV CAASQGCMNN ITIGDDQWGY YETVAGGAGA
GPGWHGAGGV HTHMTNTRIT DPEILELRYP MILKRFCLRT DGSGGRGKYV GGEGVERDLL
FRKPVTLSVL TERRTLQPYG LAGGGPGKSG RNLIIKHDGR VIALAGKTCI DVEAGDTFAM
KTPGGGGYGL EDDSSTVDHS KQGIENVQRF VERGTVHNYR QSQESA
//
