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Database: UniProt
Entry: B4KTU2_DROMO
LinkDB: B4KTU2_DROMO
Original site: B4KTU2_DROMO 
ID   B4KTU2_DROMO            Unreviewed;      1128 AA.
AC   B4KTU2;
DT   23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT   23-SEP-2008, sequence version 1.
DT   25-OCT-2017, entry version 63.
DE   SubName: Full=Uncharacterized protein, isoform A {ECO:0000313|EMBL:EDW10668.1};
GN   Name=Dmoj\GI18427 {ECO:0000313|EMBL:EDW10668.1};
GN   ORFNames=Dmoj_GI18427 {ECO:0000313|EMBL:EDW10668.1}, GI18427
GN   {ECO:0000313|FlyBase:FBgn0141166};
OS   Drosophila mojavensis (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha;
OC   Ephydroidea; Drosophilidae; Drosophila.
OX   NCBI_TaxID=7230 {ECO:0000313|EMBL:EDW10668.1, ECO:0000313|Proteomes:UP000009192};
RN   [1] {ECO:0000313|EMBL:EDW10668.1, ECO:0000313|Proteomes:UP000009192}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tucson 15081-1352.22 {ECO:0000313|Proteomes:UP000009192};
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 Genomes Consortium;
RA   Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B.,
RA   Markow T.A., Kaufman T.C., Kellis M., Gelbart W., Iyer V.N.,
RA   Pollard D.A., Sackton T.B., Larracuente A.M., Singh N.D., Abad J.P.,
RA   Abt D.N., Adryan B., Aguade M., Akashi H., Anderson W.W.,
RA   Aquadro C.F., Ardell D.H., Arguello R., Artieri C.G., Barbash D.A.,
RA   Barker D., Barsanti P., Batterham P., Batzoglou S., Begun D.,
RA   Bhutkar A., Blanco E., Bosak S.A., Bradley R.K., Brand A.D.,
RA   Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA   Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA   Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA   Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A.,
RA   Daub J., David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H.,
RA   Edwards K., Eickbush T., Evans J.D., Filipski A., Findeiss S.,
RA   Freyhult E., Fulton L., Fulton R., Garcia A.C., Gardiner A.,
RA   Garfield D.A., Garvin B.E., Gibson G., Gilbert D., Gnerre S.,
RA   Godfrey J., Good R., Gotea V., Gravely B., Greenberg A.J.,
RA   Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A., Haerty W.,
RA   Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA   Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A.,
RA   Hubisz M.J., Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S.,
RA   Jeck W.R., Johnson J., Jones C.D., Jordan W.C., Karpen G.H.,
RA   Kataoka E., Keightley P.D., Kheradpour P., Kirkness E.F.,
RA   Koerich L.B., Kristiansen K., Kudrna D., Kulathinal R.J., Kumar S.,
RA   Kwok R., Lander E., Langley C.H., Lapoint R., Lazzaro B.P., Lee S.J.,
RA   Levesque L., Li R., Lin C.F., Lin M.F., Lindblad-Toh K., Llopart A.,
RA   Long M., Low L., Lozovsky E., Lu J., Luo M., Machado C.A.,
RA   Makalowski W., Marzo M., Matsuda M., Matzkin L., McAllister B.,
RA   McBride C.S., McKernan B., McKernan K., Mendez-Lago M., Minx P.,
RA   Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E., Negre B.,
RA   Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA   Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S.,
RA   Pesole G., Phillippy A.M., Ponting C.P., Pop M., Porcelli D.,
RA   Powell J.R., Prohaska S., Pruitt K., Puig M., Quesneville H.,
RA   Ram K.R., Rand D., Rasmussen M.D., Reed L.K., Reenan R., Reily A.,
RA   Remington K.A., Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H.,
RA   Rohde C., Rozas J., Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L.,
RA   Sanchez-Gracia A., Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C.,
RA   Schlenke T., Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M.,
RA   Sisneros N.B., Smith C.D., Smith T.F., Spieth J., Stage D.E.,
RA   Stark A., Stephan W., Strausberg R.L., Strempel S., Sturgill D.,
RA   Sutton G., Sutton G.G., Tao W., Teichmann S., Tobari Y.N.,
RA   Tomimura Y., Tsolas J.M., Valente V.L., Venter E., Venter J.C.,
RA   Vicario S., Vieira F.G., Vilella A.J., Villasante A., Walenz B.,
RA   Wang J., Wasserman M., Watts T., Wilson D., Wilson R.K., Wing R.A.,
RA   Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G., Yamamoto D.,
RA   Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E., Zhang P.,
RA   Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA   Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A.,
RA   An P., Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P.,
RA   Barry A., Bayul T., Berlin A., Bessette D., Bloom T., Blye J.,
RA   Boguslavskiy L., Bonnet C., Boukhgalter B., Bourzgui I., Brown A.,
RA   Cahill P., Channer S., Cheshatsang Y., Chuda L., Citroen M.,
RA   Collymore A., Cooke P., Costello M., D'Aco K., Daza R., De Haan G.,
RA   DeGray S., DeMaso C., Dhargay N., Dooley K., Dooley E., Doricent M.,
RA   Dorje P., Dorjee K., Dupes A., Elong R., Falk J., Farina A., Faro S.,
RA   Ferguson D., Fisher S., Foley C.D., Franke A., Friedrich D.,
RA   Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA   Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA   Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA   Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA   Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F.,
RA   LeVine R., Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T.,
RA   Lokyitsang Y., Lubonja R., Lui A., MacDonald P., Magnisalis V.,
RA   Maru K., Matthews C., McCusker W., McDonough S., Mehta T., Meldrim J.,
RA   Meneus L., Mihai O., Mihalev A., Mihova T., Mittelman R., Mlenga V.,
RA   Montmayeur A., Mulrain L., Navidi A., Naylor J., Negash T., Nguyen T.,
RA   Nguyen N., Nicol R., Norbu C., Norbu N., Novod N., O'Neill B.,
RA   Osman S., Markiewicz E., Oyono O.L., Patti C., Phunkhang P.,
RA   Pierre F., Priest M., Raghuraman S., Rege F., Reyes R., Rise C.,
RA   Rogov P., Ross K., Ryan E., Settipalli S., Shea T., Sherpa N., Shi L.,
RA   Shih D., Sparrow T., Spaulding J., Stalker J., Stange-Thomann N.,
RA   Stavropoulos S., Stone C., Strader C., Tesfaye S., Thomson T.,
RA   Thoulutsang Y., Thoulutsang D., Topham K., Topping I., Tsamla T.,
RA   Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M., Wilkinson J.,
RA   Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D., Zimmer A.,
RA   Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J., Chin C.,
RA   Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- SIMILARITY: Belongs to the transient receptor (TC 1.A.4) family.
CC       {ECO:0000256|SAAS:SAAS00933551}.
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DR   EMBL; CH933808; EDW10668.1; -; Genomic_DNA.
DR   RefSeq; XP_002006733.1; XM_002006697.2.
DR   EnsemblMetazoa; FBtr0169152; FBpp0167644; FBgn0141166.
DR   GeneID; 6580936; -.
DR   KEGG; dmo:Dmoj_GI18427; -.
DR   FlyBase; FBgn0141166; Dmoj\GI18427.
DR   InParanoid; B4KTU2; -.
DR   KO; K13803; -.
DR   OMA; SCMKWRR; -.
DR   OrthoDB; EOG091G029I; -.
DR   PhylomeDB; B4KTU2; -.
DR   Proteomes; UP000009192; Unassembled WGS sequence.
DR   Bgee; FBgn0141166; -.
DR   GO; GO:0034703; C:cation channel complex; IEA:EnsemblMetazoa.
DR   GO; GO:0030425; C:dendrite; IEA:EnsemblMetazoa.
DR   GO; GO:0016027; C:inaD signaling complex; IEA:EnsemblMetazoa.
DR   GO; GO:0005622; C:intracellular; IEA:EnsemblMetazoa.
DR   GO; GO:0035997; C:rhabdomere microvillus membrane; IEA:EnsemblMetazoa.
DR   GO; GO:0005262; F:calcium channel activity; IEA:EnsemblMetazoa.
DR   GO; GO:0005516; F:calmodulin binding; IEA:EnsemblMetazoa.
DR   GO; GO:0042802; F:identical protein binding; IEA:EnsemblMetazoa.
DR   GO; GO:0010461; F:light-activated ion channel activity; IEA:EnsemblMetazoa.
DR   GO; GO:0046982; F:protein heterodimerization activity; IEA:EnsemblMetazoa.
DR   GO; GO:0007589; P:body fluid secretion; IEA:EnsemblMetazoa.
DR   GO; GO:0019722; P:calcium-mediated signaling; IEA:EnsemblMetazoa.
DR   GO; GO:0071454; P:cellular response to anoxia; IEA:EnsemblMetazoa.
DR   GO; GO:0007603; P:phototransduction, visible light; IEA:EnsemblMetazoa.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:EnsemblMetazoa.
DR   CDD; cd00204; ANK; 1.
DR   Gene3D; 1.25.40.20; -; 1.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR020683; Ankyrin_rpt-contain_dom.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR004729; TRP_channel.
DR   InterPro; IPR013555; TRP_dom.
DR   InterPro; IPR002153; TRPC_channel.
DR   PANTHER; PTHR10117; PTHR10117; 1.
DR   Pfam; PF13606; Ank_3; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF08344; TRP_2; 1.
DR   PRINTS; PR01097; TRNSRECEPTRP.
DR   SMART; SM00248; ANK; 2.
DR   SUPFAM; SSF48403; SSF48403; 1.
DR   TIGRFAMs; TIGR00870; trp; 1.
DR   PROSITE; PS50297; ANK_REP_REGION; 1.
DR   PROSITE; PS50088; ANK_REPEAT; 1.
PE   3: Inferred from homology;
KW   ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023,
KW   ECO:0000256|SAAS:SAAS00933366};
KW   Complete proteome {ECO:0000313|Proteomes:UP000009192};
KW   Ion channel {ECO:0000256|SAAS:SAAS00931870};
KW   Ion transport {ECO:0000256|SAAS:SAAS00929079};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000009192};
KW   Repeat {ECO:0000256|SAAS:SAAS00931009};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|SAAS:SAAS00927442}.
FT   TRANSMEM    336    356       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    368    389       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    552    574       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    638    660       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       42    179       ANK_REP_REGION. {ECO:0000259|PROSITE:
FT                                PS50297}.
FT   REPEAT      147    179       ANK. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00023}.
SQ   SEQUENCE   1128 AA;  128579 MW;  3581A58218A1C6B2 CRC64;
     MGRKKRQPMG LPPGGAPKTV GGCCVPLGLP QPLLLEEKKF LLAVERGDIP NVRRILQKAL
     RQQHININCM DPLGRRALTL AIDNENLEMV ELLVIMGVET KDALLHAINA EFVEAVELLL
     EHEELIFKEG ELYSWQKVDI NTAMFPPDIT PLMLAAHKNN FEILRILLDR GAAVPVPHDI
     RCGCGECVRL MAEDSLRHSL SRVNIYRALC SPSLICLTSS DPILTAFQLS WELRNLALTE
     QECKLEYMDL RRQCQKFACC LLDQTRSSNE LAIILNYDPT ISSYEPGDRM SLTRLVQAIS
     YKQKKFVAHS NIQQLLSSIW YDGLPGFRRK GIVDRFICIA QVALLFPLYC CIYMFAPNCR
     TGRLMRKPFM KFLIHASSYV FFLFILILVS QRADDDFVRL FGTARMKAEL AEQEQRQRGQ
     APSKLELLVV LYVIGFMWEE IQEIFAVGMQ NYLRNMWNFI DFLRNSLYVS VMCLRAFAYI
     QQATEIARDP QMAFIPREKW HDFDPQLIAE GLFAAANVFS ALKLVHLFSI NPHLGPLQIS
     LGRMVIDIVK FFFIYTLVLF AFACGLNQLL WYFAALEKSK CYVLPDGEAD WASHGDSCMK
     WRRFGNLFES SQSLFWASFG MVGLDDFELT GIKSYTRFWG LLMFGSYSVI NVIVLLNLLI
     AMMSNSYAMI DEHSDTEWKF ARTKLWMSYF EDSPTLPPPF NVLPSVKWLI RVFRKSSKAI
     DRQRSKKRQE QEQYSKYDNI MRSLVWRYIS AMHRKFENNP VTEDDINEVK SEISTMRYEM
     LEIFENSGMD VSSANKKEKH PRPRRMKVWE RRLMKGFQVA PVQASSEPEL LGNVNGEGEM
     REVKVESVPS RPAKETARER FQRVARTVLL QSSTHKWNVV LQGTLQNSQI GRSTKHQRKS
     LHNLGKAIEE ARKLILLNPN CASGRESPIR IEFEDEKTST LLELLNQISE EINHPRQSIK
     PCWRPPLSTV STRAMAASND WSRSHTAPEL QLNRKSAPQP QQQPQPQPTP SRVANRTREL
     PLCPSKLVTA SAPTAKKTAP SAPHAPAPAA KAPATVNSGN RARATMPFSV ELGLGRGSLY
     RVQPSHSNAF DIHVVDLDER NPSNTALDKD NMSDVSSVLS MSPKRPNP
//
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