ID B4LIM8_DROVI Unreviewed; 1779 AA.
AC B4LIM8;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 24-JAN-2024, entry version 96.
DE RecName: Full=AT-rich interactive domain-containing protein 2 {ECO:0008006|Google:ProtNLM};
GN Name=Dvir\GJ21457 {ECO:0000313|EMBL:EDW60398.1};
GN ORFNames=Dvir_GJ21457 {ECO:0000313|EMBL:EDW60398.1};
OS Drosophila virilis (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila.
OX NCBI_TaxID=7244 {ECO:0000313|EMBL:EDW60398.1, ECO:0000313|Proteomes:UP000008792};
RN [1] {ECO:0000313|EMBL:EDW60398.1, ECO:0000313|Proteomes:UP000008792}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tucson 15010-1051.87 {ECO:0000313|Proteomes:UP000008792};
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RA Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B., Markow T.A.,
RA Kaufman T.C., Kellis M., Gelbart W., Iyer V.N., Pollard D.A., Sackton T.B.,
RA Larracuente A.M., Singh N.D., Abad J.P., Abt D.N., Adryan B., Aguade M.,
RA Akashi H., Anderson W.W., Aquadro C.F., Ardell D.H., Arguello R.,
RA Artieri C.G., Barbash D.A., Barker D., Barsanti P., Batterham P.,
RA Batzoglou S., Begun D., Bhutkar A., Blanco E., Bosak S.A., Bradley R.K.,
RA Brand A.D., Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A., Daub J.,
RA David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H., Edwards K.,
RA Eickbush T., Evans J.D., Filipski A., Findeiss S., Freyhult E., Fulton L.,
RA Fulton R., Garcia A.C., Gardiner A., Garfield D.A., Garvin B.E., Gibson G.,
RA Gilbert D., Gnerre S., Godfrey J., Good R., Gotea V., Gravely B.,
RA Greenberg A.J., Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A.,
RA Haerty W., Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A., Hubisz M.J.,
RA Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S., Jeck W.R.,
RA Johnson J., Jones C.D., Jordan W.C., Karpen G.H., Kataoka E.,
RA Keightley P.D., Kheradpour P., Kirkness E.F., Koerich L.B., Kristiansen K.,
RA Kudrna D., Kulathinal R.J., Kumar S., Kwok R., Lander E., Langley C.H.,
RA Lapoint R., Lazzaro B.P., Lee S.J., Levesque L., Li R., Lin C.F., Lin M.F.,
RA Lindblad-Toh K., Llopart A., Long M., Low L., Lozovsky E., Lu J., Luo M.,
RA Machado C.A., Makalowski W., Marzo M., Matsuda M., Matzkin L.,
RA McAllister B., McBride C.S., McKernan B., McKernan K., Mendez-Lago M.,
RA Minx P., Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E.,
RA Negre B., Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S., Pesole G.,
RA Phillippy A.M., Ponting C.P., Pop M., Porcelli D., Powell J.R.,
RA Prohaska S., Pruitt K., Puig M., Quesneville H., Ram K.R., Rand D.,
RA Rasmussen M.D., Reed L.K., Reenan R., Reily A., Remington K.A.,
RA Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H., Rohde C., Rozas J.,
RA Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L., Sanchez-Gracia A.,
RA Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C., Schlenke T.,
RA Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M., Sisneros N.B.,
RA Smith C.D., Smith T.F., Spieth J., Stage D.E., Stark A., Stephan W.,
RA Strausberg R.L., Strempel S., Sturgill D., Sutton G., Sutton G.G., Tao W.,
RA Teichmann S., Tobari Y.N., Tomimura Y., Tsolas J.M., Valente V.L.,
RA Venter E., Venter J.C., Vicario S., Vieira F.G., Vilella A.J.,
RA Villasante A., Walenz B., Wang J., Wasserman M., Watts T., Wilson D.,
RA Wilson R.K., Wing R.A., Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G.,
RA Yamamoto D., Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E.,
RA Zhang P., Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA Bayul T., Berlin A., Bessette D., Bloom T., Blye J., Boguslavskiy L.,
RA Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA Chin C., Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
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DR EMBL; CH940648; EDW60398.1; -; Genomic_DNA.
DR RefSeq; XP_002049205.1; XM_002049169.2.
DR STRING; 7244.B4LIM8; -.
DR EnsemblMetazoa; FBtr0237382; FBpp0235874; FBgn0208583.
DR GeneID; 6624857; -.
DR KEGG; dvi:6624857; -.
DR eggNOG; KOG2312; Eukaryota.
DR HOGENOM; CLU_001971_0_0_1; -.
DR InParanoid; B4LIM8; -.
DR OMA; IPAKVQP; -.
DR OrthoDB; 5001776at2759; -.
DR PhylomeDB; B4LIM8; -.
DR Proteomes; UP000008792; Unassembled WGS sequence.
DR GO; GO:0035060; C:brahma complex; IEA:EnsemblMetazoa.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006338; P:chromatin remodeling; IEA:EnsemblMetazoa.
DR GO; GO:0008587; P:imaginal disc-derived wing margin morphogenesis; IEA:EnsemblMetazoa.
DR GO; GO:0008586; P:imaginal disc-derived wing vein morphogenesis; IEA:EnsemblMetazoa.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:EnsemblMetazoa.
DR GO; GO:0050821; P:protein stabilization; IEA:EnsemblMetazoa.
DR Gene3D; 1.10.150.60; ARID DNA-binding domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR001606; ARID_dom.
DR InterPro; IPR036431; ARID_dom_sf.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR003150; DNA-bd_RFX.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR22970; AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 2; 1.
DR PANTHER; PTHR22970:SF14; AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 2; 1.
DR Pfam; PF01388; ARID; 1.
DR Pfam; PF02257; RFX_DNA_binding; 1.
DR SMART; SM01014; ARID; 1.
DR SMART; SM00501; BRIGHT; 1.
DR SUPFAM; SSF46774; ARID-like; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS51011; ARID; 1.
DR PROSITE; PS51526; RFX_DBD; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008792}.
FT DOMAIN 93..186
FT /note="ARID"
FT /evidence="ECO:0000259|PROSITE:PS51011"
FT DOMAIN 750..833
FT /note="RFX-type winged-helix"
FT /evidence="ECO:0000259|PROSITE:PS51526"
FT REGION 17..59
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 836..891
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 906..931
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1014..1040
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1065..1106
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 17..37
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 45..59
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 836..855
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 876..891
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1020..1040
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1066..1106
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1779 AA; 193258 MW; C3983C4DB620BAEE CRC64;
MTSIDNVRVL LQSLPAASPA VGNSNNNAQQ NESTPAKLGA AATPLRARNT QQQQQQQQQQ
QQLQLQQLQA QPQFFYGTPE KSTTGSTVGG KQLRAPEEFW RDLHQFHERR GTPLTQAAKI
SGQHVDLYRL YQEVTERGGF NKVNMRDEWD EVYSALDTLR DRCVNGTAGI KHIYRRYLDK
YERLNFLGED PDKLEALEAV IECADLGASA SRARSRALAG GGVGGVGGSL TGGGWGSIFG
MPHSTLTAVP MAYNQRQHMV NADRRRQYKM STQLHKHSSY EKLLLSLISP LPNEQDFAIN
VCTLMANEQR PTLQLNECPK LLDVLLAHLG VYADYSMRQL FQHGHNNAGM QVRRHSKLNF
WRDLLYDKPQ ILDLYTDEQA WLDNGLINKE TDACNDYLFQ SDELDFELDF LNLRRSHGTD
ERIGQRVLQI VQLLRSLSFH QDNVTLLASN RTLWRYLVMG ANVRWSNIHI QALETAGNLA
QQFDLLDPAT DELSRNLLAT LCEGVESNDR AVIISCLEIL YKLCGREGNA QHINRCLGLD
FYQRVMLLLS LTDVMLLIFT LEAIYALSSL GARPCSMLMQ VRGLLDQLVA LLTVEAQSYG
AAGCILMRVV EVVPGNMLST LAQTIPGTQM TQLMTVKQPQ QPAPIAALPP PAPTQVQVLP
PQPETVSVSV PAPVPTTTPA PAPAAVSLPV PSLPQVQLPM PSLPQVQLPP PPTQQVSMPA
PAAGTVVLPG TLPAAPSAPQ SFTHDDETYA LAWLGATYER AGNGHEYRVE QQELYTIYLS
HCQKAGKLSV VNRLQFPRLV RLIFNASVGP AIVRQMDGTD LPGTHYVGIR MRAQPLPMQQ
QHQQQQQQQQ KAAAAATATA AKKEPALVPK SETTVVDASD EATGTQTPSS SLIKSLLANK
VNERQLKQKA QAQPPALVAT TASATGSPAS QPIKVTSTAI SAFVNNPLMQ HTPVKVGQTT
IKPLHPQLAL EKKPMTDSAP PPLAPLSGSN VLTKDAQGRT VIIQSKRKLT IDEEQNKRLA
LDSSSNTPAG KDEPQVTPSK NAANLYADLA ASILEDEDLD DVPPLAASSQ EQQQTTLQQQ
QQQQHQQHQQ QHQQQHQQQQ HQQQLQLIPA KVQPAQRQLI FPAGSAGAPP PQLKLATTAT
IKTDQGLQTV PVILQKTEQQ QQQQPQQPTQ TQYVLATNQQ GQTYLVAQQT APVAAAANTP
ATPTLLVTQA AQQQTKTIII LQQPGVSASN VPGTQKVIMT TAQGQQVLVT TTTAPAVGQP
RPAAQVQQQL QQQQQIFLNP QRTVPAALGA GQMSPSLLSQ LNQIPATIKL HQPQPSQSPQ
LHRGGIVATK TAPIPQLQQH QSIIQQHIIS GPAAAAEKRQ LLLGGIKETT LITQTPATAA
PLQQSQLNSQ TIITTQPPAA TTPVVGAALQ QQQQHIRSVL EQQQQHHPSI IQQKITMPTV
LTETVKAKAA PAAATIAKKP MAPPTSSLPV QQQQQQQPVQ MPALKSTQQL QQQAQLVSSE
SKPSIMIEAK PAEQSTITAT STVAAMPATA ATAIASTTTT ATSIVSNSNP TAAGAAASAV
PVDVNWLFIC DWRNCPRRKF KSLNELQHHV CNVHCPDHLD SGAEIYCQWG SGPSLCDNIA
RKRYSLMTHL VDRHLALDDL RASVQRRLAT GIHNVAPTQP TVTIVRNVGN ASNAPASTAA
TTAAAAPATT ATAVGTSALQ AIKRHSADFL NSKELLDENE GPVTKSIRLT AALILRNLVN
YTSTAKRSLK RYEPHLANVA FSNVEASGVL SHILHELSQ
//
