ID B4M3X7_DROVI Unreviewed; 1859 AA.
AC B4M3X7;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 2.
DT 27-MAR-2024, entry version 81.
DE SubName: Full=Uncharacterized protein, isoform A {ECO:0000313|EMBL:EDW59338.2};
GN Name=Dvir\GJ10335 {ECO:0000313|EMBL:EDW59338.2};
GN ORFNames=Dvir_GJ10335 {ECO:0000313|EMBL:EDW59338.2};
OS Drosophila virilis (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila.
OX NCBI_TaxID=7244 {ECO:0000313|EMBL:EDW59338.2, ECO:0000313|Proteomes:UP000008792};
RN [1] {ECO:0000313|EMBL:EDW59338.2, ECO:0000313|Proteomes:UP000008792}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tucson 15010-1051.87 {ECO:0000313|Proteomes:UP000008792};
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RA Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B., Markow T.A.,
RA Kaufman T.C., Kellis M., Gelbart W., Iyer V.N., Pollard D.A., Sackton T.B.,
RA Larracuente A.M., Singh N.D., Abad J.P., Abt D.N., Adryan B., Aguade M.,
RA Akashi H., Anderson W.W., Aquadro C.F., Ardell D.H., Arguello R.,
RA Artieri C.G., Barbash D.A., Barker D., Barsanti P., Batterham P.,
RA Batzoglou S., Begun D., Bhutkar A., Blanco E., Bosak S.A., Bradley R.K.,
RA Brand A.D., Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A., Daub J.,
RA David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H., Edwards K.,
RA Eickbush T., Evans J.D., Filipski A., Findeiss S., Freyhult E., Fulton L.,
RA Fulton R., Garcia A.C., Gardiner A., Garfield D.A., Garvin B.E., Gibson G.,
RA Gilbert D., Gnerre S., Godfrey J., Good R., Gotea V., Gravely B.,
RA Greenberg A.J., Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A.,
RA Haerty W., Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A., Hubisz M.J.,
RA Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S., Jeck W.R.,
RA Johnson J., Jones C.D., Jordan W.C., Karpen G.H., Kataoka E.,
RA Keightley P.D., Kheradpour P., Kirkness E.F., Koerich L.B., Kristiansen K.,
RA Kudrna D., Kulathinal R.J., Kumar S., Kwok R., Lander E., Langley C.H.,
RA Lapoint R., Lazzaro B.P., Lee S.J., Levesque L., Li R., Lin C.F., Lin M.F.,
RA Lindblad-Toh K., Llopart A., Long M., Low L., Lozovsky E., Lu J., Luo M.,
RA Machado C.A., Makalowski W., Marzo M., Matsuda M., Matzkin L.,
RA McAllister B., McBride C.S., McKernan B., McKernan K., Mendez-Lago M.,
RA Minx P., Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E.,
RA Negre B., Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S., Pesole G.,
RA Phillippy A.M., Ponting C.P., Pop M., Porcelli D., Powell J.R.,
RA Prohaska S., Pruitt K., Puig M., Quesneville H., Ram K.R., Rand D.,
RA Rasmussen M.D., Reed L.K., Reenan R., Reily A., Remington K.A.,
RA Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H., Rohde C., Rozas J.,
RA Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L., Sanchez-Gracia A.,
RA Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C., Schlenke T.,
RA Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M., Sisneros N.B.,
RA Smith C.D., Smith T.F., Spieth J., Stage D.E., Stark A., Stephan W.,
RA Strausberg R.L., Strempel S., Sturgill D., Sutton G., Sutton G.G., Tao W.,
RA Teichmann S., Tobari Y.N., Tomimura Y., Tsolas J.M., Valente V.L.,
RA Venter E., Venter J.C., Vicario S., Vieira F.G., Vilella A.J.,
RA Villasante A., Walenz B., Wang J., Wasserman M., Watts T., Wilson D.,
RA Wilson R.K., Wing R.A., Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G.,
RA Yamamoto D., Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E.,
RA Zhang P., Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA Bayul T., Berlin A., Bessette D., Bloom T., Blye J., Boguslavskiy L.,
RA Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA Chin C., Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
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DR EMBL; CH940652; EDW59338.2; -; Genomic_DNA.
DR RefSeq; XP_002056226.2; XM_002056190.2.
DR EnsemblMetazoa; FBtr0226260; FBpp0224752; FBgn0197621.
DR GeneID; 6632586; -.
DR KEGG; dvi:6632586; -.
DR eggNOG; KOG2039; Eukaryota.
DR HOGENOM; CLU_244339_0_0_1; -.
DR OrthoDB; 3152325at2759; -.
DR Proteomes; UP000008792; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0016043; P:cellular component organization; IEA:UniProt.
DR GO; GO:0060255; P:regulation of macromolecule metabolic process; IEA:UniProt.
DR CDD; cd19757; Bbox1; 1.
DR CDD; cd16449; RING-HC; 1.
DR CDD; cd20379; Tudor_dTUD-like; 1.
DR Gene3D; 2.30.30.140; -; 5.
DR Gene3D; 2.40.50.90; -; 4.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR039117; RNF17.
DR InterPro; IPR035437; SNase_OB-fold_sf.
DR InterPro; IPR002999; Tudor.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR018957; Znf_C3HC4_RING-type.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR16442; RING FINGER PROTEIN 17; 1.
DR PANTHER; PTHR16442:SF1; RING FINGER PROTEIN 17; 1.
DR Pfam; PF00567; TUDOR; 5.
DR Pfam; PF00643; zf-B_box; 1.
DR Pfam; PF00097; zf-C3HC4; 1.
DR SMART; SM00336; BBOX; 2.
DR SMART; SM00184; RING; 1.
DR SMART; SM00333; TUDOR; 5.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 5.
DR PROSITE; PS50304; TUDOR; 2.
DR PROSITE; PS50119; ZF_BBOX; 2.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000008792};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}.
FT DOMAIN 26..76
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 144..186
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT DOMAIN 206..246
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT DOMAIN 1326..1386
FT /note="Tudor"
FT /evidence="ECO:0000259|PROSITE:PS50304"
FT DOMAIN 1699..1759
FT /note="Tudor"
FT /evidence="ECO:0000259|PROSITE:PS50304"
FT REGION 429..493
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1491..1510
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1535..1599
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 429..466
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1491..1507
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1535..1564
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1565..1580
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1859 AA; 211406 MW; 0198A2F16CF65A54 CRC64;
MITDDSGVKF FDRKFVAANL RSQLRCPKCT REYSHKHTKG VAAENHRPFL LPCGHNMCEF
CISKHRQQMD FKCAVCYSSA QPTITAKDPN GKYVGNIRDY YELNYHVLGE TNSLEYYRRY
SVDSVNNSLL CPSNMSEIVL ETKCSECGHC AAGGECKQCN AFYCKRCFET VHHHSRVLKT
HIFQRLVDKK RASRGIRVGN DIFRMPAQLM CSAHNAPAHI YCTTCKRNTC DSCATKQHFN
HITCTVGEMN HRYVAEIPTT INSIDAALLQ INNAQLVVKN TKDKLGNFAA ETLDSITERF
RLLHGQLQNA QLQAIEMLRE SSLSPQVQLN MAMSQLNGYE TVLKNLRQIL HSGVNDRLEV
PQDIWLKDVI VIVTEHLEKI PTYVQVTKIN NNPYHLNTTN NLSELIEKHF ECHFVDPQIK
VRFNNEYGHQ STISDSSQPH NSCESSVSNS WPDQKAAHLS PTTGSAHGKK QKRRPKKIKS
SCSSMNSNVG EQPAQQHNFV HTFSAMDISK SNSMQSASNN LLNPMGGWFH TDAMVRVRSI
QSPEDFYVQC INAAQRIREQ LEAFAETPDC KPPDVIVVGQ QYITCHSQTE MDRWHRALVS
QKAEMRDIYN VFLPDIGLSH MVHSNNFRRL PDHLATLPYA AVHCSLKQLM PSNGGTEWEP
QAGAFLKQMV QDNPVHVTVM HASGSQLYEV DLIVNNYESN ISVRESFLYT GMARARGLAT
TQVPQPQQLM ALQSQRLPKF VPHVGDVLII QMLHVEHPQE FYVMPHELEL KRCTLQRELQ
GFMDHLSLSQ LEPIYLGRLQ LSCVIQSEGQ WQRACIEHML PEGYVRVRLV DSGISQKLYW
DQLFMLPHKF WTQELAIKCR LADVETLQEH NYAWTPAAID AFKQLTSNPK LQMEVVYVRD
EVAHVAIHFT RSGNEQNNVG AMLVAQGHCQ SSGESSRVIK PQPGRHSQLD ADTRKLIEEA
KLQLQPSMPF KTSDRQNRSQ IEVIYVEHPG EFYVTLTHFV SALAKLRKTV QVNADEMYQT
HALKQNWQPG DMCFVRVMAK GDLEVLWHRG QIVGPTQGAN SKYNVRLRDI GELALGVPSS
SLTIMDEVLE RVSNSALCCR LYGIIPNGAE WSPEDIEFFK TQLQAYSTLH VIGHGRDGGR
TRVTLWGGHT EISGPFSPAR IKYTNINELL LQKDRALSDP LMLLQQDLPL LASSSSRSSS
QREDDDDDDA ELLACLEKVG RTTGSVTLPQ DSYFKQDFEH NDEMPPLELL KDLNINTPTT
GCSEPPPAWL QPRQCKKSIF TALPTYVNHQ CEVYLSLATD ESFIHHMRNL LVKHFKPLLE
KQEPSIYVVG QPVVVIYHLD NLFYRGIVQS KLSPKGEHKV YYVDYGNEEK VKPAQMLPYA
PFPQLSSLCW RVGIHGVQPK QKNYTLTTMD TVHQTVVMKL SSVRVVEPQG ANGLPQCQLK
VGDMDIATMM LNNEMAVRVP LQSDHEIKQK RAEILKIFKV FDELKQLSEF QPPITGGQAN
TTAQPPPTKK KYMMDSREMQ RLDFQTDFDC KEAAEPKLQT SVDFEKGDSD ADDSIEKNSN
EGFSDDYVDE EVDEGISNDD DNENTASPVS EQDSFIPPRG ISAMDQMRRR IQLRYKERLE
SAHFSPMDTS TERSYHDGDG CFKPQCLPTG VNQFTCSIDK VLSATELQIT PQLTEFAKQQ
IVLAQETSAL IREAAQLNPV QLNTLCLARY SRDSQWYRAV IKELHQAVNQ ATVYYIDFHD
TEMLPFNDLK VMPKQLFMFP LRTCRVKLNG IKLNKNFADT SVRQALQACL CKYPSVFARV
HNPINYNDNS DDYDDSDPGS SSDSIRHGFK LYEVDIYENK YKTDLLYKPL IDSRMFVLK
//
