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Database: UniProt
Entry: B4NPE3_DROWI
LinkDB: B4NPE3_DROWI
Original site: B4NPE3_DROWI 
ID   B4NPE3_DROWI            Unreviewed;      3135 AA.
AC   B4NPE3;
DT   23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 2.
DT   27-SEP-2017, entry version 63.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EDW86383.2};
GN   Name=Dwil\GK17712 {ECO:0000313|EMBL:EDW86383.2};
GN   ORFNames=Dwil_GK17712 {ECO:0000313|EMBL:EDW86383.2}, GK17712
GN   {ECO:0000313|FlyBase:FBgn0219711};
OS   Drosophila willistoni (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha;
OC   Ephydroidea; Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7260 {ECO:0000313|EMBL:EDW86383.2, ECO:0000313|Proteomes:UP000007798};
RN   [1] {ECO:0000313|EMBL:EDW86383.2, ECO:0000313|Proteomes:UP000007798}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tucson 14030-0811.24 {ECO:0000313|Proteomes:UP000007798};
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 Genomes Consortium;
RA   Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B.,
RA   Markow T.A., Kaufman T.C., Kellis M., Gelbart W., Iyer V.N.,
RA   Pollard D.A., Sackton T.B., Larracuente A.M., Singh N.D., Abad J.P.,
RA   Abt D.N., Adryan B., Aguade M., Akashi H., Anderson W.W.,
RA   Aquadro C.F., Ardell D.H., Arguello R., Artieri C.G., Barbash D.A.,
RA   Barker D., Barsanti P., Batterham P., Batzoglou S., Begun D.,
RA   Bhutkar A., Blanco E., Bosak S.A., Bradley R.K., Brand A.D.,
RA   Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA   Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA   Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA   Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A.,
RA   Daub J., David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H.,
RA   Edwards K., Eickbush T., Evans J.D., Filipski A., Findeiss S.,
RA   Freyhult E., Fulton L., Fulton R., Garcia A.C., Gardiner A.,
RA   Garfield D.A., Garvin B.E., Gibson G., Gilbert D., Gnerre S.,
RA   Godfrey J., Good R., Gotea V., Gravely B., Greenberg A.J.,
RA   Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A., Haerty W.,
RA   Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA   Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A.,
RA   Hubisz M.J., Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S.,
RA   Jeck W.R., Johnson J., Jones C.D., Jordan W.C., Karpen G.H.,
RA   Kataoka E., Keightley P.D., Kheradpour P., Kirkness E.F.,
RA   Koerich L.B., Kristiansen K., Kudrna D., Kulathinal R.J., Kumar S.,
RA   Kwok R., Lander E., Langley C.H., Lapoint R., Lazzaro B.P., Lee S.J.,
RA   Levesque L., Li R., Lin C.F., Lin M.F., Lindblad-Toh K., Llopart A.,
RA   Long M., Low L., Lozovsky E., Lu J., Luo M., Machado C.A.,
RA   Makalowski W., Marzo M., Matsuda M., Matzkin L., McAllister B.,
RA   McBride C.S., McKernan B., McKernan K., Mendez-Lago M., Minx P.,
RA   Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E., Negre B.,
RA   Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA   Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S.,
RA   Pesole G., Phillippy A.M., Ponting C.P., Pop M., Porcelli D.,
RA   Powell J.R., Prohaska S., Pruitt K., Puig M., Quesneville H.,
RA   Ram K.R., Rand D., Rasmussen M.D., Reed L.K., Reenan R., Reily A.,
RA   Remington K.A., Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H.,
RA   Rohde C., Rozas J., Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L.,
RA   Sanchez-Gracia A., Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C.,
RA   Schlenke T., Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M.,
RA   Sisneros N.B., Smith C.D., Smith T.F., Spieth J., Stage D.E.,
RA   Stark A., Stephan W., Strausberg R.L., Strempel S., Sturgill D.,
RA   Sutton G., Sutton G.G., Tao W., Teichmann S., Tobari Y.N.,
RA   Tomimura Y., Tsolas J.M., Valente V.L., Venter E., Venter J.C.,
RA   Vicario S., Vieira F.G., Vilella A.J., Villasante A., Walenz B.,
RA   Wang J., Wasserman M., Watts T., Wilson D., Wilson R.K., Wing R.A.,
RA   Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G., Yamamoto D.,
RA   Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E., Zhang P.,
RA   Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA   Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A.,
RA   An P., Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P.,
RA   Barry A., Bayul T., Berlin A., Bessette D., Bloom T., Blye J.,
RA   Boguslavskiy L., Bonnet C., Boukhgalter B., Bourzgui I., Brown A.,
RA   Cahill P., Channer S., Cheshatsang Y., Chuda L., Citroen M.,
RA   Collymore A., Cooke P., Costello M., D'Aco K., Daza R., De Haan G.,
RA   DeGray S., DeMaso C., Dhargay N., Dooley K., Dooley E., Doricent M.,
RA   Dorje P., Dorjee K., Dupes A., Elong R., Falk J., Farina A., Faro S.,
RA   Ferguson D., Fisher S., Foley C.D., Franke A., Friedrich D.,
RA   Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA   Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA   Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA   Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA   Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F.,
RA   LeVine R., Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T.,
RA   Lokyitsang Y., Lubonja R., Lui A., MacDonald P., Magnisalis V.,
RA   Maru K., Matthews C., McCusker W., McDonough S., Mehta T., Meldrim J.,
RA   Meneus L., Mihai O., Mihalev A., Mihova T., Mittelman R., Mlenga V.,
RA   Montmayeur A., Mulrain L., Navidi A., Naylor J., Negash T., Nguyen T.,
RA   Nguyen N., Nicol R., Norbu C., Norbu N., Novod N., O'Neill B.,
RA   Osman S., Markiewicz E., Oyono O.L., Patti C., Phunkhang P.,
RA   Pierre F., Priest M., Raghuraman S., Rege F., Reyes R., Rise C.,
RA   Rogov P., Ross K., Ryan E., Settipalli S., Shea T., Sherpa N., Shi L.,
RA   Shih D., Sparrow T., Spaulding J., Stalker J., Stange-Thomann N.,
RA   Stavropoulos S., Stone C., Strader C., Tesfaye S., Thomson T.,
RA   Thoulutsang Y., Thoulutsang D., Topham K., Topping I., Tsamla T.,
RA   Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M., Wilkinson J.,
RA   Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D., Zimmer A.,
RA   Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J., Chin C.,
RA   Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
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DR   EMBL; CH964291; EDW86383.2; -; Genomic_DNA.
DR   RefSeq; XP_002075397.2; XM_002075361.2.
DR   STRING; 7260.FBpp0246855; -.
DR   GeneID; 6652900; -.
DR   KEGG; dwi:Dwil_GK17712; -.
DR   FlyBase; FBgn0219711; Dwil\GK17712.
DR   eggNOG; KOG2302; Eukaryota.
DR   eggNOG; COG1226; LUCA.
DR   InParanoid; B4NPE3; -.
DR   KO; K04854; -.
DR   OrthoDB; EOG091G02L1; -.
DR   Proteomes; UP000007798; Unassembled WGS sequence.
DR   GO; GO:0005891; C:voltage-gated calcium channel complex; IEA:InterPro.
DR   GO; GO:0008332; F:low voltage-gated calcium channel activity; IEA:EnsemblMetazoa.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR005445; VDCC_T_a1.
DR   Pfam; PF00520; Ion_trans; 4.
DR   PRINTS; PR01629; TVDCCALPHA1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000007798};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007798};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    386    406       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    521    539       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    559    584       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1180   1198       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1210   1231       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1243   1263       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1309   1331       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1401   1425       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2139   2160       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2236   2258       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2339   2362       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2419   2440       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2452   2476       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2552   2572       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2637   2663       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      256    591       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN     1178   1434       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN     2100   2372       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN     2418   2672       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   COILED     1991   2022       {ECO:0000256|SAM:Coils}.
FT   COILED     2663   2686       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   3135 AA;  343966 MW;  222C4F7EAA5E97C1 CRC64;
     MLQQAAIIES AAGAGVGVVG GARANQTANN GQRRRVAGAS AAATQQHHQR SNSKKLNQMH
     SNEEPPMTVI VDGGDGTSGA GQQSQRSSRS QGSQRVRKTS SSTNAKASTL VRATSIANSS
     AATATAAAAR HHRPHRQPSN ASASAARDRH RERDRDRDRD REPAPVRRRA GGGRRHSGVS
     STLGPLSGGN SSTASSCNGS CSSDDGDASS HTSSSSSSSS SSGEPNLPYP GFPEISMMAL
     TQYTRPRNWC LMLITNPWFE RVSILAILLN CITLGMYQPC VDDACVTNRC KILQIFDDII
     FAFFALEMTI KMVAMGMCGK NTYFADSWNR LDFFIVLSGL LEYVMHVENL NLTAIRTIRV
     LRPLRAINRI PSMRILVMLL LDTLPMLGNV LLLCFFVFFI FGIIGVQLWE GILRQRCTLD
     RSKGMIYPIT IPEVYRVRVR VNSLSQYYEF SKDQDYICST PNDSGMHLCG NFPPYRIGSL
     VCNDEAKLFD FNEPTNTSCV NWNQYYTTCQ PSFENPFQGT ISFDNIGMAW VAIFLVISLE
     GWTDIMYYVQ DAHSFWDWIY FVLLIVIGSF FMINLCLVVI ATQFSETKKR EMERMRQERA
     RYTSTSTLAS STNNSEPATC YAEIVKYIAH LWRRFKRRML KKYRLYKYQR QQRKEGLLPN
     ADNLTFSPSR IKCHHPKCPK YSARKPSSIQ DQMITVMVPL NSNNNNNNNN NSNGNGSTSN
     GNNAPSCTTV ALVNGINGSA ASVTMGPMQG QQQQHSSSEN TEQSMGGEGS GLGPRQSSLK
     KSYHSHNLQQ LKPEGSAAEQ KTILLKFPQQ VIDSEQLMSH PCTSGFLSPP TSASRRPSVM
     FNEYVLLHTP PALSNDGPSG SSAGSTAAGV MPAAGATSTL SVGASTNLNG GGGAGGGSSA
     SVGSIDKNSH NIFSTEKMTQ AGDGSIWQVN LPQSIGTIAN AYTDCSELGI HDAMTCQELL
     AFSVAFSAAL PTGQSTLESF YTSLARCDPH TAEALKQQVE QAASPMPPPI VTATTTDATT
     TTAAAAAAAA AVVSSNETPQ VAVVADVATH HATSTTNTTN TANRRSKDHH HHHNNNNNSQ
     SRNNNNGHGQ GQSHHRSRGG GGGGGGHASA ATSAVAPITG NYMEDYACCY DLYQNALSPL
     DERQRQRSPA MRCLIAVYRC LSRVCSWIRR YIRRLVEHKY FQQGILLAIL INTLSMGIEY
     HDQPAELTAI VETSNVVFSG IFAVEMLLKV VAEGPFRYIA NGFNVFDGII VILSAIEICQ
     QFVGNGTGGG GSGLSVLRTF RLLRILKLVR FMPNLRRQLF VMLRTMDNVA VFFSLLVLFI
     FIFSILGMYL FGGKFCKFLD ESGLERECTC PEIISRHPQC ECDRKHFNNI LWATVTVFQI
     LTQEDWNVVL FNGMEKTSHW AALYFVALMT FGNYVLFNLL VAILVEGFSS ERNERREREQ
     RELVKKLREE TLAENYSDGM YDESRSEADS STTNDSYYEV RNRWRSAEDV RKLQDSAELI
     IEAKSNMHRQ RLLQPTQDYQ INELPSSQGG MAAASGLADD VAGSKLMLHH GMEDAKPRGG
     LKKTYSIKDR RGDASRLSKI RLVREPPIIT TTAATPQDSP STTLDPSMSF RQWGDVEPPC
     SPSPSLLKPP NIFSGGQRTL DEGLPVPAID LIPPSPVLAH KPLNILNASQ LQGHPGSVGG
     SALASSASSG IAQLPSTLAN SMHSVIIDDI SKNSNTTVAA GTPIYVPTIS STAATLQPAV
     DSHQGHSHSL SDLSPLTVSL TGSVSVSSCA GGGASTSGSS SSERLPPIAA PPTTNSGSFK
     QRFRRSSSKK RPQRLQEDSA TGGGITVPDE EDEQQQLNNG TDSSCLMRGS GGPLASPLPQ
     GPLAHGSKDT NRLSPQNSIR RLSNTLSIGS GPVGSRRASA CIFNSQVYQN LNQPPKLRAG
     AGQRRMSSIE LAFSKTSHLN LHNLEANRKS LSYTNSKLDL DKWNKSYGNL NDPDNMLQQY
     MEARDKRKNS ISHYNLKKRL EEKELQQLQQ LHQQELMQQQ QQQCQQQQDS HQMSMMMSSG
     QLHPQYSMVP SSGEHVSKLK ILINRLTPKH FTAERESYSM YIFPEENRFR QICTWFVNQK
     WFDNVVLLFI ALNCITLAME RPNIPPSSTE RLFLSTANYV FTVVFTVEMF IKVVATGMFY
     GTDAYFTSGW NIMDGSLVTI SIIDLLMSLI SESSPRIFGI LRVFRLLRSL RPLRVINRAP
     GLKLVVQTLL SSLRPIGNIV LICCTFFIIF GILGVQLFKG TFFYCEGENI KNVRTAAECR
     SIPGNVWTNR KYNFDDLGKA LMSLFVLSSR DGWVNIMYTG LDAVGVDQQP IVNYNEWRLL
     YFIAFILLVG FFVLNMFVGV VVENFHRCRE EQEKEEKIRR AAKRALQMEK KRRRMHEPPY
     YTNYSPTRMF VHNVVTSKYF DLAIAAVIGL NVVTMAMEYY RMPNPLKYAL KIFNYFFTAV
     FILEANMKLV ALGWKLYLKD RWNQLDVGIV LLSIVGIVLE ELETKFIPIN PTIIRVMRVL
     RIARVLKLLK MAKGIRALLD TVMQALPQVG NLGLLFFLLF FIFAALGVEL FGRLECSDEI
     PCQGLGEHAH FANFGMAFLT LFRVATGDNW NGIMKDTLRD NCDDAADCVR NCCVSSVIAP
     IFFVIFVLMA QFVLVNVVVA VLMKHLEESH KQMEDELDME VELERELVRE QEFAQEQKLC
     QQLAEAQAKA PAPPRPLAKV KSLPKNFIYS TPSLDKKFPP LTLAGSLNST GGNTNTGSPG
     PNQGQTGAAT GAGARRQTVQ YFNQPPLSNG LGLSLAEMGG TLSPQVLGSP FGGLSTTAGA
     ASIAAESASL QLPPLGRRGR RASAAAGFRK RGVLSKERSL DEQAIRRRNL EAKRTSCDSL
     PWGGDALDCR RGTIFESLES EADIRSIRSA DVTRHSEPDE SLAVVSSSST SIPASPTPTP
     TPTPMPIPMA LPIGMPILTP TTPISNQPPP RRPFGWSQSV DQGCGRSSLL LSVPRSMPPR
     SRSGSTKQLF KQQALDEDAD MDESSLLLPT LSLSGGGAGA GGGSSSSSGG GGGGVGSATN
     LEDSSAQTAE ISPALTKSDS ADILRIISER RRMDQRDQQQ GGDSGGAGGN DIENEDRDND
     YNELLLVKSP QSSMD
//
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