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Database: UniProt
Entry: B4Q5A2_DROSI
LinkDB: B4Q5A2_DROSI
Original site: B4Q5A2_DROSI 
ID   B4Q5A2_DROSI            Unreviewed;      1127 AA.
AC   B4Q5A2;
DT   23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT   23-SEP-2008, sequence version 1.
DT   27-SEP-2017, entry version 49.
DE   SubName: Full=GD23440 {ECO:0000313|EMBL:EDX04035.1};
GN   Name=Dsim\GD23440 {ECO:0000313|EMBL:EDX04035.1};
GN   ORFNames=Dsim_GD23440 {ECO:0000313|EMBL:EDX04035.1}, Dsimw501_GD23440
GN   {ECO:0000313|EMBL:KMY88659.1}, GD23440
GN   {ECO:0000313|FlyBase:FBgn0194822};
OS   Drosophila simulans (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha;
OC   Ephydroidea; Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7240 {ECO:0000313|EMBL:EDX04035.1, ECO:0000313|Proteomes:UP000000304};
RN   [1] {ECO:0000313|EMBL:EDX04035.1, ECO:0000313|Proteomes:UP000000304}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Mixed {ECO:0000313|EMBL:EDX04035.1};
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 Genomes Consortium;
RA   Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B.,
RA   Markow T.A., Kaufman T.C., Kellis M., Gelbart W., Iyer V.N.,
RA   Pollard D.A., Sackton T.B., Larracuente A.M., Singh N.D., Abad J.P.,
RA   Abt D.N., Adryan B., Aguade M., Akashi H., Anderson W.W.,
RA   Aquadro C.F., Ardell D.H., Arguello R., Artieri C.G., Barbash D.A.,
RA   Barker D., Barsanti P., Batterham P., Batzoglou S., Begun D.,
RA   Bhutkar A., Blanco E., Bosak S.A., Bradley R.K., Brand A.D.,
RA   Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA   Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA   Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA   Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A.,
RA   Daub J., David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H.,
RA   Edwards K., Eickbush T., Evans J.D., Filipski A., Findeiss S.,
RA   Freyhult E., Fulton L., Fulton R., Garcia A.C., Gardiner A.,
RA   Garfield D.A., Garvin B.E., Gibson G., Gilbert D., Gnerre S.,
RA   Godfrey J., Good R., Gotea V., Gravely B., Greenberg A.J.,
RA   Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A., Haerty W.,
RA   Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA   Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A.,
RA   Hubisz M.J., Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S.,
RA   Jeck W.R., Johnson J., Jones C.D., Jordan W.C., Karpen G.H.,
RA   Kataoka E., Keightley P.D., Kheradpour P., Kirkness E.F.,
RA   Koerich L.B., Kristiansen K., Kudrna D., Kulathinal R.J., Kumar S.,
RA   Kwok R., Lander E., Langley C.H., Lapoint R., Lazzaro B.P., Lee S.J.,
RA   Levesque L., Li R., Lin C.F., Lin M.F., Lindblad-Toh K., Llopart A.,
RA   Long M., Low L., Lozovsky E., Lu J., Luo M., Machado C.A.,
RA   Makalowski W., Marzo M., Matsuda M., Matzkin L., McAllister B.,
RA   McBride C.S., McKernan B., McKernan K., Mendez-Lago M., Minx P.,
RA   Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E., Negre B.,
RA   Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA   Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S.,
RA   Pesole G., Phillippy A.M., Ponting C.P., Pop M., Porcelli D.,
RA   Powell J.R., Prohaska S., Pruitt K., Puig M., Quesneville H.,
RA   Ram K.R., Rand D., Rasmussen M.D., Reed L.K., Reenan R., Reily A.,
RA   Remington K.A., Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H.,
RA   Rohde C., Rozas J., Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L.,
RA   Sanchez-Gracia A., Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C.,
RA   Schlenke T., Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M.,
RA   Sisneros N.B., Smith C.D., Smith T.F., Spieth J., Stage D.E.,
RA   Stark A., Stephan W., Strausberg R.L., Strempel S., Sturgill D.,
RA   Sutton G., Sutton G.G., Tao W., Teichmann S., Tobari Y.N.,
RA   Tomimura Y., Tsolas J.M., Valente V.L., Venter E., Venter J.C.,
RA   Vicario S., Vieira F.G., Vilella A.J., Villasante A., Walenz B.,
RA   Wang J., Wasserman M., Watts T., Wilson D., Wilson R.K., Wing R.A.,
RA   Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G., Yamamoto D.,
RA   Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E., Zhang P.,
RA   Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA   Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A.,
RA   An P., Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P.,
RA   Barry A., Bayul T., Berlin A., Bessette D., Bloom T., Blye J.,
RA   Boguslavskiy L., Bonnet C., Boukhgalter B., Bourzgui I., Brown A.,
RA   Cahill P., Channer S., Cheshatsang Y., Chuda L., Citroen M.,
RA   Collymore A., Cooke P., Costello M., D'Aco K., Daza R., De Haan G.,
RA   DeGray S., DeMaso C., Dhargay N., Dooley K., Dooley E., Doricent M.,
RA   Dorje P., Dorjee K., Dupes A., Elong R., Falk J., Farina A., Faro S.,
RA   Ferguson D., Fisher S., Foley C.D., Franke A., Friedrich D.,
RA   Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA   Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA   Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA   Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA   Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F.,
RA   LeVine R., Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T.,
RA   Lokyitsang Y., Lubonja R., Lui A., MacDonald P., Magnisalis V.,
RA   Maru K., Matthews C., McCusker W., McDonough S., Mehta T., Meldrim J.,
RA   Meneus L., Mihai O., Mihalev A., Mihova T., Mittelman R., Mlenga V.,
RA   Montmayeur A., Mulrain L., Navidi A., Naylor J., Negash T., Nguyen T.,
RA   Nguyen N., Nicol R., Norbu C., Norbu N., Novod N., O'Neill B.,
RA   Osman S., Markiewicz E., Oyono O.L., Patti C., Phunkhang P.,
RA   Pierre F., Priest M., Raghuraman S., Rege F., Reyes R., Rise C.,
RA   Rogov P., Ross K., Ryan E., Settipalli S., Shea T., Sherpa N., Shi L.,
RA   Shih D., Sparrow T., Spaulding J., Stalker J., Stange-Thomann N.,
RA   Stavropoulos S., Stone C., Strader C., Tesfaye S., Thomson T.,
RA   Thoulutsang Y., Thoulutsang D., Topham K., Topping I., Tsamla T.,
RA   Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M., Wilkinson J.,
RA   Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D., Zimmer A.,
RA   Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J., Chin C.,
RA   Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
RN   [2] {ECO:0000313|EMBL:EDX04035.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Mixed {ECO:0000313|EMBL:EDX04035.1};
RG   FlyBase;
RL   Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EMBL:KMY88659.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=W501 {ECO:0000313|EMBL:KMY88659.1};
RX   PubMed=22936249; DOI=10.1101/gr.141689.112;
RA   Hu T.T., Eisen M.B., Thornton K.R., Andolfatto P.;
RT   "A second-generation assembly of the Drosophila simulans genome
RT   provides new insights into patterns of lineage-specific divergence.";
RL   Genome Res. 23:89-98(2013).
RN   [4] {ECO:0000313|EMBL:KMY88659.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=W501 {ECO:0000313|EMBL:KMY88659.1};
RA   Hu T., Eisen M.B., Thornton K.R., Andolfatto P.;
RL   Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
RN   [5] {ECO:0000313|EMBL:KMY88659.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=W501 {ECO:0000313|EMBL:KMY88659.1};
RG   FlyBase;
RL   Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CM000361; EDX04035.1; -; Genomic_DNA.
DR   EMBL; CM002910; KMY88659.1; -; Genomic_DNA.
DR   RefSeq; XP_002078450.1; XM_002078414.2.
DR   EnsemblMetazoa; FBtr0223350; FBpp0221842; FBgn0194822.
DR   GeneID; 6731294; -.
DR   KEGG; dsi:Dsimw501_GD23440; -.
DR   FlyBase; FBgn0194822; Dsim\GD23440.
DR   KO; K06671; -.
DR   OMA; ICDLLII; -.
DR   OrthoDB; EOG091G0195; -.
DR   PhylomeDB; B4Q5A2; -.
DR   Proteomes; UP000000304; Chromosome 2L.
DR   Bgee; FBgn0194822; -.
DR   GO; GO:0008278; C:cohesin complex; IEA:EnsemblMetazoa.
DR   GO; GO:0000780; C:condensed nuclear chromosome, centromeric region; IEA:EnsemblMetazoa.
DR   GO; GO:0005721; C:pericentric heterochromatin; IEA:EnsemblMetazoa.
DR   GO; GO:0000922; C:spindle pole; IEA:EnsemblMetazoa.
DR   GO; GO:0035327; C:transcriptionally active chromatin; IEA:EnsemblMetazoa.
DR   GO; GO:0003682; F:chromatin binding; IEA:EnsemblMetazoa.
DR   GO; GO:0016322; P:neuron remodeling; IEA:EnsemblMetazoa.
DR   GO; GO:0007130; P:synaptonemal complex assembly; IEA:EnsemblMetazoa.
DR   Gene3D; 1.25.10.10; -; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR020839; SCD.
DR   InterPro; IPR013721; STAG.
DR   Pfam; PF08514; STAG; 1.
DR   SUPFAM; SSF48371; SSF48371; 3.
DR   PROSITE; PS51425; SCD; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000304};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000304}.
FT   DOMAIN      326    411       SCD. {ECO:0000259|PROSITE:PS51425}.
FT   COILED      290    317       {ECO:0000256|SAM:Coils}.
FT   COILED     1097   1120       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   1127 AA;  130118 MW;  A26AB73C95F5FAD3 CRC64;
     MMARRGGKRI RMDDPPPDYD ELHSDALNES TSDADSPTKR MTRLRARGGV RDKPPIIDDD
     EDEFFAPIAR KRKTPATRKG PTERKERVER PRKEPVDKGH HERIDSEREI TTDENSLYYI
     VRHSKNPIAS IVDQWIEQYK ANRETALVAL MQFFINASGC KGKISEDIQY PVDHTSIIRR
     MTEEFDEESG EYPLIMTGTQ WRKFKNNFCD FVQTLVKQCQ YSIIYDQFLM DNVISLLTGL
     SDSQVRAFRH TATLAAMKLM TALVDVALLV SNNFDNAAKQ FEAERVKSRD RRASDRLDSL
     MTKRSELEEN MDEIKSMLTY MFKSVFVHRY RDSLPDIRAI CMAEIGIWME NYPQNFLDDS
     YLKYIGWTLH DKIGEVRLRC LQSLLPLYEK DELKGKLELF TSKFKDRIVA MTLDKEFEVS
     VHAVKLVISI LKIHPEILAD KDCEIVYELV YSSHRGVAQA AAEFLNVRLF HLTADMEETK
     TKRGKVRMPN TPLVRDLVQF FIESELHEHG AYLVDSFIDS NDMVRDWECM TDLLLEEPGP
     NEEVLDNKQE STLIEIMVSS VKQSATGEVP VGRASNRKCT LSAKELKAIQ DEKAKLTEHF
     IVTLPSLLEK YQADSEKLAN LLAVPQYFDL NLYTTNRQEG NLQALLDRIN QVMSMHTGRE
     VLETCAKTLE CLCAEGSATY TRCNIARSNI IESAVNKYKD AIEEWRNLIQ GEETPNEDDI
     YNITITLKVL SILYSSHNLN PWELFKSLFQ DVEEAQSKEN IDRCLPNEAL VYCIEACYFS
     ISWGLQYVEN ECESVNVTEV VAELRNNLDT FMGACFELTR DGPTVQIQEA AYQSICDLLI
     IFSDKLARSE IEHIRGLEYK SRMDEHLILD NFVQHYVFSL KQDVAQDETR IEELHKKRNF
     LACYCKLVVY NIIPTMRAAS IFKYYVKCYN DYGDIIKATL GKAREINKVN FAMTLLLSLI
     TVFKSLQEQS EDGTVSKSSQ EFVDLKELAK RFALTFGFDA IKNRESVAAI HRGGIYFAAN
     KEPDDPVRAP TRLLFLEVLN EFNYKLLKQD KKVIMSFLDK IIPPAMPSSR AEEWQPLILY
     RNSLLHGETD QAPVASKRAY TRKRRDHDEE EEEEEDEEEH NDPDYRG
//
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