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Database: UniProt
Entry: B4RVP7
LinkDB: B4RVP7
Original site: B4RVP7 
ID   DAPD_ALTMD              Reviewed;         274 AA.
AC   B4RVP7; F2GBY5;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   23-SEP-2008, sequence version 1.
DT   19-FEB-2014, entry version 44.
DE   RecName: Full=2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase;
DE            EC=2.3.1.117;
DE   AltName: Full=Tetrahydrodipicolinate N-succinyltransferase;
DE            Short=THP succinyltransferase;
DE            Short=Tetrahydropicolinate succinylase;
GN   Name=dapD; OrderedLocusNames=MADE_1004950;
OS   Alteromonas macleodii (strain DSM 17117 / Deep ecotype).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Alteromonadaceae; Alteromonas.
OX   NCBI_TaxID=314275;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17117 / Deep ecotype;
RX   PubMed=18670397; DOI=10.1038/ismej.2008.74;
RA   Ivars-Martinez E., Martin-Cuadrado A.-B., D'Auria G., Mira A.,
RA   Ferriera S., Johnson J., Friedman R., Rodriguez-Valera F.;
RT   "Comparative genomics of two ecotypes of the marine planktonic
RT   copiotroph Alteromonas macleodii suggests alternative lifestyles
RT   associated with different kinds of particulate organic matter.";
RL   ISME J. 2:1194-1212(2008).
CC   -!- CATALYTIC ACTIVITY: Succinyl-CoA + (S)-2,3,4,5-tetrahydropyridine-
CC       2,6-dicarboxylate + H(2)O = CoA + N-succinyl-L-2-amino-6-
CC       oxoheptanedioate.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-lysine biosynthesis via DAP
CC       pathway; LL-2,6-diaminopimelate from (S)-tetrahydrodipicolinate
CC       (succinylase route): step 1/3.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the transferase hexapeptide repeat family.
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DR   EMBL; CP001103; AEA97136.1; -; Genomic_DNA.
DR   RefSeq; YP_004426134.1; NC_011138.3.
DR   ProteinModelPortal; B4RVP7; -.
DR   SMR; B4RVP7; 1-274.
DR   STRING; 314275.MADE_03035; -.
DR   PRIDE; B4RVP7; -.
DR   EnsemblBacteria; AEA97136; AEA97136; MADE_1004950.
DR   GeneID; 10556331; -.
DR   KEGG; amc:MADE_1004950; -.
DR   eggNOG; COG2171; -.
DR   KO; K00674; -.
DR   OMA; LYFRVND; -.
DR   BioCyc; AMAC314275:GHA7-1005-MONOMER; -.
DR   UniPathway; UPA00034; UER00019.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008666; F:2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0019877; P:diaminopimelate biosynthetic process; IEA:UniProtKB-HAMAP.
DR   GO; GO:0009089; P:lysine biosynthetic process via diaminopimelate; IEA:UniProtKB-HAMAP.
DR   Gene3D; 1.10.166.10; -; 1.
DR   HAMAP; MF_00811; DapD; 1.
DR   InterPro; IPR005664; DapD_Trfase_Hexpep_rpt_fam.
DR   InterPro; IPR001451; Hexapep_transf.
DR   InterPro; IPR018357; Hexapep_transf_CS.
DR   InterPro; IPR023180; THP_succinylTrfase_dom1.
DR   InterPro; IPR011004; Trimer_LpxA-like.
DR   PANTHER; PTHR19136:SF52; PTHR19136:SF52; 1.
DR   Pfam; PF00132; Hexapep; 1.
DR   SUPFAM; SSF51161; SSF51161; 1.
DR   TIGRFAMs; TIGR00965; dapD; 1.
DR   PROSITE; PS00101; HEXAPEP_TRANSFERASES; 1.
PE   3: Inferred from homology;
KW   Acyltransferase; Amino-acid biosynthesis; Complete proteome;
KW   Cytoplasm; Diaminopimelate biosynthesis; Lysine biosynthesis; Repeat;
KW   Transferase.
FT   CHAIN         1    274       2,3,4,5-tetrahydropyridine-2,6-
FT                                dicarboxylate N-succinyltransferase.
FT                                /FTId=PRO_1000134027.
SQ   SEQUENCE   274 AA;  29280 MW;  BEE513784EFAED22 CRC64;
     MNELKAIIED AFENRDSISP SSAPDEVRDA VAQAIDLLNS GKGRVAEKIA GEWVVHQWLK
     KAVLLFFRLH NNDVIEGAES KFYDKVPLKY TNYTAEQFAA DGARIVPPAA VRTGTFVGKN
     AVVMPSYVNI GAFVDEGTMV DTWATVGSCA QIGKNVHLSG GVGIGGVLEP LQANPTIIED
     NCFIGARSEI VEGVIVEEGS VISMGVYIGQ STRIYDRETG EIHYGRVPAG SVVVAGNLPS
     ADGKYSLYAA IIVKKVDAKT RAKVGINALL RGVE
//
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