ID B4S851_PROA2 Unreviewed; 389 AA.
AC B4S851;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE SubName: Full=Efflux transporter, RND family, MFP subunit {ECO:0000313|EMBL:ACF46238.1};
DE Flags: Precursor;
GN OrderedLocusNames=Paes_1210 {ECO:0000313|EMBL:ACF46238.1};
OS Prosthecochloris aestuarii (strain DSM 271 / SK 413).
OC Bacteria; Chlorobiota; Chlorobiia; Chlorobiales; Chlorobiaceae;
OC Prosthecochloris.
OX NCBI_TaxID=290512 {ECO:0000313|EMBL:ACF46238.1, ECO:0000313|Proteomes:UP000002725};
RN [1] {ECO:0000313|EMBL:ACF46238.1, ECO:0000313|Proteomes:UP000002725}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 271 / SK 413 {ECO:0000313|Proteomes:UP000002725};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Schmutz J., Larimer F., Land M.,
RA Hauser L., Kyrpides N., Anderson I., Liu Z., Li T., Zhao F., Overmann J.,
RA Bryant D.A., Richardson P.;
RT "Complete sequence of chromosome of Prosthecochloris aestuarii DSM 271.";
RL Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; CP001108; ACF46238.1; -; Genomic_DNA.
DR RefSeq; WP_012505773.1; NC_011059.1.
DR AlphaFoldDB; B4S851; -.
DR STRING; 290512.Paes_1210; -.
DR KEGG; paa:Paes_1210; -.
DR eggNOG; COG0845; Bacteria.
DR HOGENOM; CLU_018816_14_5_10; -.
DR Proteomes; UP000002725; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469:SF33; EFFLUX PROTEIN; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002725};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 9..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 59..272
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
SQ SEQUENCE 389 AA; 42924 MW; 65923C94FB98F233 CRC64;
MKLSTTQKIV AGVTVVVIAI LFILMMPAPL PVDTEIVRRG VLTVRLEGEG RSRVKERFTI
SSPVNGRLER ILLDEGDSVT SNAVVARITP PSLNTREYTR AEAAMRSSEA ALGAAGARER
QVKVDLEQAR RKYDRYTVLF EQGAVSKEEY EEVKATRDML AKEYSAATMT TRSSRFDVDA
ARAVVDSALE GSFFEVRSPR DGLVLKILEK SERIIAAGTP LVEIGDAHDI ELVIDVLSSD
AVKVAPGMQV VIEEWGGGSA LQGRVRFIEP AAVTKISSLG IEEKRVNIII DLDEPERRLG
DNYRVQADIV LWRGDNVLQV PVSSLFRGDE DWEVFTVRRG RAIVQPVTIG RRGAYEAEVI
DGVREGDLVV VHPTNDLEDG MRVKTLKGR
//
