ID B4VXA1_9CYAN Unreviewed; 1372 AA.
AC B4VXA1;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE RecName: Full=TIR domain-containing protein {ECO:0000259|PROSITE:PS50104};
GN ORFNames=MC7420_3763 {ECO:0000313|EMBL:EDX73589.1};
OS Coleofasciculus chthonoplastes PCC 7420.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Coleofasciculales;
OC Coleofasciculaceae; Coleofasciculus.
OX NCBI_TaxID=118168 {ECO:0000313|EMBL:EDX73589.1, ECO:0000313|Proteomes:UP000003835};
RN [1] {ECO:0000313|EMBL:EDX73589.1, ECO:0000313|Proteomes:UP000003835}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 7420 {ECO:0000313|EMBL:EDX73589.1,
RC ECO:0000313|Proteomes:UP000003835};
RA Tandeau de Marsac N., Ferriera S., Johnson J., Kravitz S., Beeson K.,
RA Sutton G., Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; DS989857; EDX73589.1; -; Genomic_DNA.
DR RefSeq; WP_006103290.1; NZ_DS989857.1.
DR STRING; 118168.MC7420_3763; -.
DR eggNOG; COG2319; Bacteria.
DR HOGENOM; CLU_002676_0_0_3; -.
DR OrthoDB; 434800at2; -.
DR Proteomes; UP000003835; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd00200; WD40; 3.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 3.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 5.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR22847:SF637; WD REPEAT DOMAIN 5; 1.
DR PANTHER; PTHR22847; WD40 REPEAT PROTEIN; 1.
DR Pfam; PF13676; TIR_2; 3.
DR Pfam; PF00400; WD40; 14.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00255; TIR; 3.
DR SMART; SM00320; WD40; 14.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 3.
DR SUPFAM; SSF50978; WD40 repeat-like; 2.
DR PROSITE; PS50104; TIR; 3.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 14.
DR PROSITE; PS50294; WD_REPEATS_REGION; 14.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000003835};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT TRANSMEM 675..696
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 3..157
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
FT DOMAIN 234..368
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
FT DOMAIN 436..582
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
FT REPEAT 771..812
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 812..853
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 853..885
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 894..926
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 935..967
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 976..1008
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1018..1050
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1059..1100
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1100..1141
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1141..1173
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1183..1224
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1223..1257
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1264..1296
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1305..1339
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT COILED 634..673
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1372 AA; 155435 MW; E93029DEFCF9BBAF CRC64;
MTTFFDAFIS YGRADSKAFA QKLQARLDEQ GFKVWFDFND IPLAVDFQNQ IDDGIEKASH
FLFIIAPHSV NSPYCLKEIE LAIKLNKRII PLLHLMQISP ETWQQRNPNG TPEEWEAYKA
KGLHESYQNM HPTIQKLNWV YFQEGIDDFE KSFADLVKLL RSHHDYVEKH TRFLLKALEW
ERNKKQTNYL LTGEEKKQAE AWLKIRFKDE QPPCTPTNLH CEYITESIKN ANNLMTQVFL
SYADEDRTTM ERIRNSLRQE SITVWTNTSD IQTGEAFEEA IKRGIEQADN LVLLLSPESV
NSTYCQQELD LALSLHKRII PVLVREIEPN QVPTGLRDLQ YIDLTDNVKE DDYLLDESQL
LKTLHQDAAY YNEHKILLTK SLKWQQQQKN PSILLRGYNL HSAEAWLKVA QKRTQHPPTP
LQEEFIAESL RQPPLESLDV FISYSRADSD FARMLNDALQ MQGKTTWFDQ ESIASGSDFQ
EEIYRGIRVC DNFLFILSPR SVNSPYCADE VEYAAKLNKR FVTVLHQPVN TAELHPELAK
VQWIDFNQNQ RDFNANFNQL VRTLDTDREH VHSHSKWLQR ALEWQQKGKS ADLLLRGSEF
AVAENWLQET EQQKKKPTAT LLQKAFIQAS QNAIAAAKEA EKRRQAEMLR LQEERMKEAE
ARLVEQKKSA RRQKYFFIAI GITFMALVGA AGVVWVQREL FQDSQISSVS RFSLLLSKTD
QKLDALIEAI RAGKSLQERR VIPVQPETRN HVLTALQQVV YQYGFRERNR LVGHKYGVWG
VRFSPDSKMV ASASGDRTVK LWSLDGRELA TLNGHNRQVN SVAWSPNGQT IATASNDQTA
KLWSLDGKEL ATLNGHNHQV KSIDWSPDGQ FLATASEDET VRLWSRDGKL LKTFQGHNNA
VYSVSFSPDG QTIASASEDE TVRLWSRDGK LLKTFQGHNN AVYSVSFSPD GQTIASASGD
NTVKLWSRDG KVLKTFKGHN QPVNSVSFSP DGQTIASASL DQTVRLWNRD NAIPELTLKG
HEDQVNSVSF SPDGQTIASA SLDQTIRLWN FGGKQLKTLK GHTNTVNHVS FSPDGKTIAS
TSADKTIKLW SVDGRQLNTL TGHSDLVRSV VWSLDGQTLA SASADKTIKL WSVDGRQLNT
LTGHSDLVRS LSFSPDSKTI ASTSWDKTVR LWNRDKAILQ LTLTGHNNDV NSVSFSPDGK
MLASASDDKT IKLWSVNGKE LNSLQDNDKV YSISFSPSGQ TIASAGEDTT VKLWSVDHKR
AKIIKGHSKP VYDVSFSPDG ETIASGSWDK TVKLWNKKGQ IMQTLEGHTN LVFSVAFSPD
DKMLASASAD NTVILWNLED LTLDSLMQDA CDWVGDYLKY NAPENDKHLC DN
//
