ID B4W0J6_9CYAN Unreviewed; 1218 AA.
AC B4W0J6;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 86.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=MC7420_930 {ECO:0000313|EMBL:EDX72261.1};
OS Coleofasciculus chthonoplastes PCC 7420.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Coleofasciculales;
OC Coleofasciculaceae; Coleofasciculus.
OX NCBI_TaxID=118168 {ECO:0000313|EMBL:EDX72261.1, ECO:0000313|Proteomes:UP000003835};
RN [1] {ECO:0000313|EMBL:EDX72261.1, ECO:0000313|Proteomes:UP000003835}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 7420 {ECO:0000313|EMBL:EDX72261.1,
RC ECO:0000313|Proteomes:UP000003835};
RA Tandeau de Marsac N., Ferriera S., Johnson J., Kravitz S., Beeson K.,
RA Sutton G., Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- SIMILARITY: In the N-terminal section; belongs to the phytochrome
CC family. {ECO:0000256|ARBA:ARBA00006402}.
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DR EMBL; DS989865; EDX72261.1; -; Genomic_DNA.
DR RefSeq; WP_006104538.1; NZ_DS989865.1.
DR AlphaFoldDB; B4W0J6; -.
DR STRING; 118168.MC7420_930; -.
DR eggNOG; COG2203; Bacteria.
DR eggNOG; COG2205; Bacteria.
DR eggNOG; COG2905; Bacteria.
DR HOGENOM; CLU_268932_0_0_3; -.
DR OrthoDB; 415806at2; -.
DR Proteomes; UP000003835; Unassembled WGS sequence.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd04620; CBS_two-component_sensor_histidine_kinase_repeat1; 1.
DR CDD; cd17774; CBS_two-component_sensor_histidine_kinase_repeat2; 1.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 3.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 2.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR016132; Phyto_chromo_attachment.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 3.
DR PANTHER; PTHR43711:SF24; SENSOR HISTIDINE KINASE RPPB; 1.
DR PANTHER; PTHR43711; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF00571; CBS; 2.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08447; PAS_3; 2.
DR Pfam; PF13426; PAS_9; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00116; CBS; 3.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00086; PAC; 3.
DR SMART; SM00091; PAS; 3.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 2.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 3.
DR PROSITE; PS51371; CBS; 3.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 2.
DR PROSITE; PS50112; PAS; 3.
DR PROSITE; PS50046; PHYTOCHROME_2; 1.
PE 3: Inferred from homology;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000003835}.
FT DOMAIN 110..173
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 177..255
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 264..320
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 409..545
FT /note="Phytochrome chromophore attachment site"
FT /evidence="ECO:0000259|PROSITE:PS50046"
FT DOMAIN 618..682
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 733..803
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 807..859
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 860..933
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 934..986
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 1004..1218
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 559..611
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 970..1000
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1218 AA; 138200 MW; BA9C42A88106A375 CRC64;
MSLLDLSLSS LPLEAVIDPY PLSVAPDTTL SEVIRLIAQE AGCDCTLGLS DTSTKSCHPL
PDWRLMKQAR TSCVLVMQGM QLLGLLTEQD FVRLAALDIN LDALTAADVM TRKLVILNAS
DCQDVTIILN LFQQHGIHHL PIFNESGYLL GIVTPQRMRH LLQMTDVMGL HSVAEVMTTQ
VICAPPTAPV QKLAQLMATH GVGYVVIVRQ REQGTGETVT DLDFSSVLSF RQFPIPMGIV
TADDIVQFQT LPLDFQQLDA QTVMSSAWFS IRADDFLGTA YQRMQQWHTQ QLIVLGNQGE
WQGMIDQDSL LRAINLNSKT FSFLNPILPS ISPANAELTP KTDTQSQLIL SQGGFCTNDT
INSDKKIPKP APTNQVPYEG GEGSTLNTQH SAKEHLLYSI SSRIRQSLHL EDILKTTLQE
VREWLQVDRV LIYRFHSDWS GTVMVESVGA EWDSLSGVVV HDPCFEKTSV ESYKNGRFQA
TADIYTAGLT PCHVELLASL QVRANLVISI IKDDELWGLL TAQQCHAPRQ WQTSEIELLQ
QLAVQVGIGI QQSSLFEQVQ TELIQRKRVE LELQQAKQEL ERRVEERTAQ LQQSNQKLQH
EIAERQQVEI QLRQKLAAIE ATTEGIAILN AKGEYTYLNP AHVQLFGYDT SEALLGKSWR
HLYPPEEITR FERDIFTILQ QQGYWRGEAV ALRQNGSKFA EEVSLTLTPE GNFICICRDI
TQRQQTEAAL RTSEERFRST FEQVTVGITH TGWDDRFLRV NQTFCDIVGY TVDELLTKTF
VDITHPDDVD GDKYYVNQLL AGEIKTFSME KRYIRKDGSI VWVNLRGSLV RKSTGELDYF
VGVIEDIRDR KRTEAALQES EQRFRQLAEN IHEVFWITDV AKSQMIYVSP AYQQIWGRSC
QSIYDNPLSF VETIHPEDRE RVMAAFAKQA RGEYHEDYRI IQPGGEQRWI RDRAFPVYDT
SGQVYRIVGI AEDITEYKQA EQEIRQALAR EQELNELKSR FISMTSHEFR TPLTTILSST
ELLKYYSSKF TEEKKQIHFE RIQSNVHHIT QMLNDILLLG KAEAGKLDFN PAQMDVRQFC
QQLVEEFQQG IGHRHSLCFT HQGQLTPVSL DEKLLRHILG NLLSNALKYS PIDRPVCLEL
TCRHNELIFR IKDQGIGISE TDQQRLFESF HRGTNVGNIS GTGLGLSIVK KAVDRHGGTI
NLESKLGVGT TFTVVIRL
//
