ID B4W0L0_9CYAN Unreviewed; 878 AA.
AC B4W0L0;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE RecName: Full=CHASE2 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=MC7420_1002 {ECO:0000313|EMBL:EDX72333.1};
OS Coleofasciculus chthonoplastes PCC 7420.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Coleofasciculales;
OC Coleofasciculaceae; Coleofasciculus.
OX NCBI_TaxID=118168 {ECO:0000313|EMBL:EDX72333.1, ECO:0000313|Proteomes:UP000003835};
RN [1] {ECO:0000313|EMBL:EDX72333.1, ECO:0000313|Proteomes:UP000003835}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 7420 {ECO:0000313|EMBL:EDX72333.1,
RC ECO:0000313|Proteomes:UP000003835};
RA Tandeau de Marsac N., Ferriera S., Johnson J., Kravitz S., Beeson K.,
RA Sutton G., Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; DS989865; EDX72333.1; -; Genomic_DNA.
DR RefSeq; WP_006104610.1; NZ_DS989865.1.
DR AlphaFoldDB; B4W0L0; -.
DR STRING; 118168.MC7420_1002; -.
DR eggNOG; COG2114; Bacteria.
DR eggNOG; COG4252; Bacteria.
DR HOGENOM; CLU_000445_85_1_3; -.
DR OrthoDB; 337251at2; -.
DR Proteomes; UP000003835; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd07302; CHD; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR007890; CHASE2.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR PANTHER; PTHR43081:SF16; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC; 1.
DR PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR Pfam; PF05226; CHASE2; 1.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR Pfam; PF08448; PAS_4; 1.
DR SMART; SM01080; CHASE2; 1.
DR SMART; SM00044; CYCc; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000003835};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 376..398
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 404..425
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 466..502
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 545..597
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 640..766
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
FT COILED 448..476
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 878 AA; 98037 MW; EFFD4E840A07DBFF CRC64;
MWQKLKQNIS KWQGVLITAP TVAGLVIATA WTGSFQLLEW ATLDQFFQQR PQEPVDPRIL
VITIDESDIT QIGTWPIPDQ VLAQLLRKIN AQQPRAIGLD LYRDLPVEPG HQELVEVFQS
TPNLIGVEKV VGETVAPSPT LKQLDQVAMA DLVLDADGKV RRGLLSVQLD DESIHLGLGV
KLALMYLDAE GITLQMTDEA KSHLQLGKAE FVPLAGNEGG YVNADVGGYQ ILLNYRGPRE
NFQTVSIADI LENRIPPDLM RDRIILIGAT GQSANDLFFT PYSQNTIGSR QQTPGVIIHA
NIASQIISGA MAGRPLIKAI DGRPLIPFID RINQPSWLTI WVDPVEWLWI VVWSFIGAGG
SWKLQQANQF ADRIFPRWMV VGFGTFFMSS ILVVGSYGAF LVNWWLPVVS PLVALIGSSM
AIALYQTWEL QRYNADLEIL LETTTAHSDA IEEELHQQAE EAARESERRL AQFLEAVPVG
VAVLDATGKT YYLNQRAQQL MGKGVVPDTF AEQFAEVYQF YIAGTEQLYP ADLLPVVQAL
MGESATADDI EIHQGDQIIP IEAWGIPIFD EGGKVTFAIA AFQDITERKK AEIERKDFTA
QLLQLNQAYE RFVPENFLKL LDKKSIVDVK LGEAVQKEMS ILFSDIRSFT TLSERMSLED
NFKFINAYLS RMEPAIVEHD GFIDKYIGDA IMALFNGSAD DAVRAGIDML NRLTDYNKTR
QRPDRPPIQI GIGINTGSLM LGTVGGHNRM DGTVISDAVN LAARLEQLTK EYGVSLLISH
HTFLQLNHPV EYAFRIIGQV QVKGKSEMVS VFEIFEADPP ELRSVKLMTK PDFEKALFLY
SKRLFKESAQ IFQECLQINP VDQVAQIYLD ACQKQGED
//
