ID   B4W2U5_9CYAN            Unreviewed;       526 AA.
AC   B4W2U5;
DT   23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT   23-SEP-2008, sequence version 1.
DT   24-JAN-2024, entry version 45.
DE   SubName: Full=Beta-lactamase, putative {ECO:0000313|EMBL:EDX71448.1};
GN   ORFNames=MC7420_14 {ECO:0000313|EMBL:EDX71448.1};
OS   Coleofasciculus chthonoplastes PCC 7420.
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Coleofasciculales;
OC   Coleofasciculaceae; Coleofasciculus.
OX   NCBI_TaxID=118168 {ECO:0000313|EMBL:EDX71448.1, ECO:0000313|Proteomes:UP000003835};
RN   [1] {ECO:0000313|EMBL:EDX71448.1, ECO:0000313|Proteomes:UP000003835}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 7420 {ECO:0000313|EMBL:EDX71448.1,
RC   ECO:0000313|Proteomes:UP000003835};
RA   Tandeau de Marsac N., Ferriera S., Johnson J., Kravitz S., Beeson K.,
RA   Sutton G., Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL   Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; DS989872; EDX71448.1; -; Genomic_DNA.
DR   RefSeq; WP_006105614.1; NZ_DS989872.1.
DR   AlphaFoldDB; B4W2U5; -.
DR   STRING; 118168.MC7420_14; -.
DR   eggNOG; COG2367; Bacteria.
DR   HOGENOM; CLU_031960_1_0_3; -.
DR   Proteomes; UP000003835; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008800; F:beta-lactamase activity; IEA:InterPro.
DR   GO; GO:0030655; P:beta-lactam antibiotic catabolic process; IEA:InterPro.
DR   GO; GO:0046677; P:response to antibiotic; IEA:InterPro.
DR   Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR045155; Beta-lactam_cat.
DR   InterPro; IPR000871; Beta-lactam_class-A.
DR   PANTHER; PTHR35333; BETA-LACTAMASE; 1.
DR   PANTHER; PTHR35333:SF4; SLR0121 PROTEIN; 1.
DR   Pfam; PF13354; Beta-lactamase2; 1.
DR   SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000003835};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        175..202
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          259..468
FT                   /note="Beta-lactamase class A catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF13354"
FT   REGION          1..90
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          103..172
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        137..161
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   526 AA;  57896 MW;  BDA931E16F720D35 CRC64;
     MAVSRGNPYK PDRNESKPRG IYRSRRASRQ RRPRQPLPLE DDLHPPSSSP SPRRLRAVQP
     NSANPSRPKP IPLNPTTRRS SEPSIYPNLK LPKLRTINGI PIRETPLGNR QMRRPPAATP
     LSQPLNPRRD NSPRRQTRRS TVSTQSEAKP KRQSSRSQPT QRGKSRRSRR SQKRAGIWIH
     VIRLLILGVG IGAIAGTLLS VLDPTSKMSM RSSEAAEGNL QESPTNQSIT PALPLRQEIS
     PLKAQVQTLV AKNPKLQPGV FVVDLDTGAY LDWQSHSIFP AASTIKVAIL VAFFQEVDAG
     KIRLDEPLTM EPEMIAKGSG DMQYQKPGTQ YSALEVATKM ITISDNTATN MIIHRLGGIQ
     AVNQRFISWG LTATAINNPL PDLEGTNTTN ARDMANLLYK VNQGELLSLR SRDRLLDIMQ
     RTVNNSLIPQ GLDSGATVAH KTGDIGSVLG DVGIVDMPTG KRYLIVTLVK RPHNDASASE
     LIRNLSRTVY DYFNKPTATP SLNSMPISTP AMMVSGLLIG LQGTIL
//