ID B4W8G0_9CAUL Unreviewed; 323 AA.
AC B4W8G0;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 24-JAN-2024, entry version 57.
DE RecName: Full=Glucokinase {ECO:0000256|HAMAP-Rule:MF_00524};
DE EC=2.7.1.2 {ECO:0000256|HAMAP-Rule:MF_00524};
DE AltName: Full=Glucose kinase {ECO:0000256|HAMAP-Rule:MF_00524};
GN Name=glk {ECO:0000256|HAMAP-Rule:MF_00524};
GN ORFNames=BBAL3_208 {ECO:0000313|EMBL:EDX79051.1};
OS Brevundimonas sp. BAL3.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Caulobacterales;
OC Caulobacteraceae; Brevundimonas.
OX NCBI_TaxID=391600 {ECO:0000313|EMBL:EDX79051.1, ECO:0000313|Proteomes:UP000003957};
RN [1] {ECO:0000313|EMBL:EDX79051.1, ECO:0000313|Proteomes:UP000003957}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BAL3 {ECO:0000313|EMBL:EDX79051.1,
RC ECO:0000313|Proteomes:UP000003957};
RA Hagstrom A., Ferriera S., Johnson J., Kravitz S., Beeson K., Sutton G.,
RA Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + D-glucose = ADP + D-glucose 6-phosphate + H(+);
CC Xref=Rhea:RHEA:17825, ChEBI:CHEBI:4167, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:61548, ChEBI:CHEBI:456216; EC=2.7.1.2;
CC Evidence={ECO:0000256|HAMAP-Rule:MF_00524};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00524}.
CC -!- SIMILARITY: Belongs to the bacterial glucokinase family.
CC {ECO:0000256|HAMAP-Rule:MF_00524, ECO:0000256|RuleBase:RU004046}.
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DR EMBL; DS989898; EDX79051.1; -; Genomic_DNA.
DR RefSeq; WP_008258989.1; NZ_DS989898.1.
DR AlphaFoldDB; B4W8G0; -.
DR STRING; 391600.BBAL3_208; -.
DR eggNOG; COG0837; Bacteria.
DR HOGENOM; CLU_042582_1_0_5; -.
DR OrthoDB; 9800595at2; -.
DR Proteomes; UP000003957; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004340; F:glucokinase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005536; F:glucose binding; IEA:InterPro.
DR GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-UniRule.
DR CDD; cd00012; NBD_sugar-kinase_HSP70_actin; 1.
DR Gene3D; 3.30.420.40; -; 1.
DR Gene3D; 3.40.367.20; -; 1.
DR HAMAP; MF_00524; Glucokinase; 1.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR003836; Glucokinase.
DR NCBIfam; TIGR00749; glk; 1.
DR PANTHER; PTHR47690; GLUCOKINASE; 1.
DR PANTHER; PTHR47690:SF1; GLUCOKINASE; 1.
DR Pfam; PF02685; Glucokinase; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|HAMAP-Rule:MF_00524};
KW Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00524};
KW Glycolysis {ECO:0000256|HAMAP-Rule:MF_00524};
KW Kinase {ECO:0000256|HAMAP-Rule:MF_00524, ECO:0000313|EMBL:EDX79051.1};
KW Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00524};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|HAMAP-
KW Rule:MF_00524}.
FT BINDING 9..14
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00524"
SQ SEQUENCE 323 AA; 34316 MW; 2D438422F0343E60 CRC64;
MNDKTLLVGD VGGTNARFAL ARMVDGKPVL DHHESFPAER YPTFLKGVAA FIDGCEIKPT
GGVIAVAGPV TDGAIDLTNS PWQVSESELQ TLGLKPVKLI NDFEALAWGA PVVPEDQLES
LGGPVDGDPH CTVAVLGPGT GFGVSALVRD AHGKEMAMPS EGGHACFPPG DPVEDEILRI
LRRRYDRVSI ERLICGPGLL NMHRALAEID GRETHIEDPA QITETAMKDP NSPCGATLAR
FCAILGAVAG DIALTTGARG GVYIAGGIVP RILPFIKASP FRQRFERKGR FKDYMAEIPT
KVIMHKHAAL LGAARVAFAE AEG
//
