ID   B4XAY4_MICAE            Unreviewed;       437 AA.
AC   B4XAY4;
DT   23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT   23-SEP-2008, sequence version 1.
DT   27-MAR-2024, entry version 50.
DE   SubName: Full=Microcystin synthetase {ECO:0000313|EMBL:ABV80227.1};
DE   Flags: Fragment;
GN   Name=mcyB {ECO:0000313|EMBL:ABV80227.1};
OS   Microcystis aeruginosa 20A2.
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC   Chroococcales; Microcystaceae; Microcystis.
OX   NCBI_TaxID=474417 {ECO:0000313|EMBL:ABV80227.1};
RN   [1] {ECO:0000313|EMBL:ABV80227.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=20A2 {ECO:0000313|EMBL:ABV80227.1};
RA   Okello W., Kurmayer R.;
RT   "Toxic cyanobacteria in Ugandan freshwater habitats.";
RL   Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; EU014161; ABV80227.1; -; Genomic_DNA.
DR   AlphaFoldDB; B4XAY4; -.
DR   CDD; cd05930; A_NRPS; 1.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   InterPro; IPR010071; AA_adenyl_domain.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020459; AMP-binding.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR   PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR   PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF13193; AMP-binding_C; 1.
DR   PRINTS; PR00154; AMPBINDING.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   4: Predicted;
FT   DOMAIN          2..261
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
FT   DOMAIN          317..391
FT                   /note="AMP-binding enzyme C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13193"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:ABV80227.1"
FT   NON_TER         437
FT                   /evidence="ECO:0000313|EMBL:ABV80227.1"
SQ   SEQUENCE   437 AA;  48781 MW;  45798289950DFC68 CRC64;
     DILSDSGVSL VLTQESLGDF LPQTGAESLC LDRDWEKIAT YSPENPFNLT NPENLAYVIY
     TSGSTGKPKG VMNIHRGICN TLKYTVDYYN LTSEDRILQI TSLSFDGSVW EIFSSLISGA
     SLVVAKPDGY KDLDYLIDLI VQEQVTYFTC VPSILRVFLQ HPKSKYCHCL KRVIVGGEAL
     SYELNQRFFQ QLNCELYNAY GPTEAAVETT IWCCQPNSQI SIGTPVANAQ VYILDSYLQP
     VPIGVAGELH IGGMGLARGY LNRPELTAEK FIPHPFAEGK LYKTGDLARY LPEGNIEYLG
     RIDNQVKLRG LRIELGEIEA VLETHSEVEK AVVILREDTS ENQRLVAYIV RKSPSLGIGE
     LRRFLQQQLP AYMVPSAFVI LSDFPLNNNG KIDRKKLPVP DETSIIESAY IAPRNEKESL
     LAQIWQDVLQ VSKIGVS
//