ID B4YSU1_9FIRM Unreviewed; 169 AA.
AC B4YSU1; C0C3H2;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 24-JAN-2024, entry version 57.
DE SubName: Full=BaiE {ECO:0000313|EMBL:ACF20986.1};
DE SubName: Full=Bile acid 7-alpha dehydratase {ECO:0000313|EMBL:EEG73348.1};
DE EC=4.2.1.106 {ECO:0000313|EMBL:EEG73348.1};
GN Name=baiE {ECO:0000313|EMBL:ACF20986.1};
GN ORFNames=CLOHYLEM_06634 {ECO:0000313|EMBL:EEG73348.1};
OS [Clostridium] hylemonae DSM 15053.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=553973 {ECO:0000313|EMBL:ACF20986.1};
RN [1] {ECO:0000313|EMBL:EEG73348.1, ECO:0000313|Proteomes:UP000004893}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15053 {ECO:0000313|EMBL:EEG73348.1,
RC ECO:0000313|Proteomes:UP000004893};
RA Sudarsanam P., Ley R., Guruge J., Turnbaugh P.J., Mahowald M., Liep D.,
RA Gordon J.;
RT "Draft genome sequence of Clostridium hylemonae (DSM 15053).";
RL Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EEG73348.1, ECO:0000313|Proteomes:UP000004893}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15053 {ECO:0000313|EMBL:EEG73348.1,
RC ECO:0000313|Proteomes:UP000004893};
RA Fulton L., Clifton S., Fulton B., Xu J., Minx P., Pepin K.H., Johnson M.,
RA Bhonagiri V., Nash W.E., Mardis E.R., Wilson R.K.;
RL Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:ACF20986.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=TN-271 {ECO:0000313|EMBL:ACF20986.1};
RX PubMed=19464381; DOI=10.1016/j.anaerobe.2009.05.004;
RA Ridlon J.M., Kang D.J., Hylemon P.B.;
RT "Isolation and characterization of a bile acid inducible 7alpha-
RT dehydroxylating operon in Clostridium hylemonae TN271.";
RL Anaerobe 16:137-146(2010).
RN [4] {ECO:0007829|PDB:4L8O}
RP X-RAY CRYSTALLOGRAPHY (2.20 ANGSTROMS).
RG Joint Center for Structural Genomics (JCSG);
RT "Crystal structure of a bile-acid 7-alpha dehydratase (CLOHYLEM_06634) from
RT Clostridium hylemonae DSM 15053 at 2.20 A resolution.";
RL Submitted (JUN-2013) to the PDB data bank.
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DR EMBL; EU675332; ACF20986.1; -; Genomic_DNA.
DR EMBL; ABYI02000028; EEG73348.1; -; Genomic_DNA.
DR RefSeq; WP_006443993.1; NZ_GG657759.1.
DR PDB; 4L8O; X-ray; 2.20 A; A=1-169.
DR PDBsum; 4L8O; -.
DR AlphaFoldDB; B4YSU1; -.
DR SMR; B4YSU1; -.
DR STRING; 553973.CLOHYLEM_06634; -.
DR KEGG; ag:ACF20986; -.
DR eggNOG; ENOG5030J1G; Bacteria.
DR HOGENOM; CLU_106738_5_0_9; -.
DR OrthoDB; 2084678at2; -.
DR BRENDA; 4.2.1.106; 14311.
DR Proteomes; UP000004893; Unassembled WGS sequence.
DR GO; GO:0033988; F:bile-acid 7alpha-dehydratase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.10.450.50; -; 1.
DR InterPro; IPR032710; NTF2-like_dom_sf.
DR InterPro; IPR037401; SnoaL-like.
DR Pfam; PF13577; SnoaL_4; 1.
DR SUPFAM; SSF54427; NTF2-like; 1.
PE 1: Evidence at protein level;
KW 3D-structure {ECO:0007829|PDB:4L8O}; Lyase {ECO:0000313|EMBL:EEG73348.1}.
FT DOMAIN 16..141
FT /note="SnoaL-like"
FT /evidence="ECO:0000259|Pfam:PF13577"
SQ SEQUENCE 169 AA; 19873 MW; EF10DD25E77A2EFC CRC64;
MSIEERLEAL EKEIQKMKDI EEIKKLKGQY FRCLDGKFWD ELETTLSPNI VTSYSNGKLV
FHGPKEVTDY FKKAMPREEI SMHMGHTPEI TIDSETTATG RWYLEDKLIF TEESKYAGSG
VNGGAFYTDK YEKVDGKWYI LETGYLRVYE EHFMRDPKIK ITMNMHKTK
//
