ID NRDR_SALPK Reviewed; 149 AA.
AC B5BDB7;
DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT 23-SEP-2008, sequence version 1.
DT 01-MAY-2013, entry version 37.
DE RecName: Full=Transcriptional repressor NrdR;
GN Name=nrdR; OrderedLocusNames=SSPA2150;
OS Salmonella paratyphi A (strain AKU_12601).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=554290;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AKU_12601;
RA Holt K.E., Thomson N.R., Wain J., Langridge G.C., Hassan R.,
RA Bhutta Z., Quail M., Norbertczak H., Danielle W., Simmonds M.,
RA White B., Bason N., Mungall K., Dougan G., Parkhill J.;
RT "Complete genome of a clinical isolate of Salmonella enterica serovar
RT Paratyphi A.";
RL Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Negatively regulates transcription of bacterial
CC ribonucleotide reductase nrd genes and operons by binding to NrdR-
CC boxes (By similarity).
CC -!- COFACTOR: Binds 1 zinc ion (By similarity).
CC -!- SIMILARITY: Belongs to the NrdR family.
CC -!- SIMILARITY: Contains 1 ATP-cone domain.
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DR EMBL; FM200053; CAR60360.1; -; Genomic_DNA.
DR RefSeq; YP_002142987.1; NC_011147.1.
DR STRING; 554290.SSPA2150; -.
DR PRIDE; B5BDB7; -.
DR EnsemblBacteria; CAR60360; CAR60360; SSPA2150.
DR GeneID; 6811465; -.
DR KEGG; sek:SSPA2150; -.
DR PATRIC; 32344483; VBISalEnt134303_2458.
DR eggNOG; COG1327; -.
DR HOGENOM; HOG000097653; -.
DR KO; K07738; -.
DR OMA; VCHERFT; -.
DR ProtClustDB; PRK00464; -.
DR BioCyc; SENT554290:GJDA-2300-MONOMER; -.
DR GO; GO:0005524; F:ATP binding; IEA:HAMAP.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:HAMAP.
DR GO; GO:0045892; P:negative regulation of transcription, DNA-dependent; IEA:HAMAP.
DR GO; GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
DR HAMAP; MF_00440; NrdR; 1; -.
DR InterPro; IPR005144; ATP-cone.
DR InterPro; IPR003796; RNR_NrdR-like.
DR Pfam; PF03477; ATP-cone; 1.
DR TIGRFAMs; TIGR00244; TIGR00244; 1.
DR PROSITE; PS51161; ATP_CONE; 1.
PE 3: Inferred from homology;
KW ATP-binding; Complete proteome; DNA-binding; Metal-binding;
KW Nucleotide-binding; Repressor; Transcription;
KW Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1 149 Transcriptional repressor NrdR.
FT /FTId=PRO_1000124546.
FT DOMAIN 49 139 ATP-cone.
FT ZN_FING 3 34 By similarity.
SQ SEQUENCE 149 AA; 17198 MW; 274B8602F5A8113E CRC64;
MHCPFCFAVD TKVIDSRLVG EGSSVRRRRQ CLVCNERFTT FEVAELVMPR VIKSNDVREP
FNEDKLRSGM LRALEKRPVS ADDVEMALNH IKSQLRATGE REVPSKMIGN LVMEQLKKLD
KVAYIRFASV YRSFEDIKDF GEEIARLQD
//
