ID B5IFE1_ACIB4 Unreviewed; 1359 AA.
AC B5IFE1;
DT 14-OCT-2008, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2008, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=Patched family protein {ECO:0000313|EMBL:ADD07832.1};
GN OrderedLocusNames=Aboo_0020 {ECO:0000313|EMBL:ADD07832.1};
OS Aciduliprofundum boonei (strain DSM 19572 / T469).
OC Archaea; Candidatus Thermoplasmatota; DHVE2 group; Aciduliprofundum.
OX NCBI_TaxID=439481 {ECO:0000313|EMBL:ADD07832.1, ECO:0000313|Proteomes:UP000001400};
RN [1] {ECO:0000313|Proteomes:UP000001400}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 19572 / T469 {ECO:0000313|Proteomes:UP000001400};
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA Pitluck S., Saunders E., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Mikhailova N., Flores G., Reysenbach A.-L., Woyke T.;
RT "Complete sequence of Aciduliprofundum boonei T469.";
RL Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP001941; ADD07832.1; -; Genomic_DNA.
DR RefSeq; WP_008085535.1; NC_013926.1.
DR STRING; 439481.Aboo_0020; -.
DR GeneID; 8826954; -.
DR KEGG; abi:Aboo_0020; -.
DR eggNOG; arCOG02174; Archaea.
DR HOGENOM; CLU_003088_0_0_2; -.
DR OrthoDB; 42357at2157; -.
DR Proteomes; UP000001400; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 2.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001400};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 15..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 793..810
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 817..837
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 843..865
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 885..905
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 917..943
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 985..1003
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1194..1213
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1219..1237
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1249..1274
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1294..1314
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1326..1350
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 817..942
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT DOMAIN 1219..1348
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
SQ SEQUENCE 1359 AA; 151363 MW; 5E14CF7B68FEA8E3 CRC64;
MELRALGNLV SKRPVATIIV ILLITSIFGF YTAQMQMSAD LSTFLPNDEM VKAQMKVSEN
FGDTDIVQVI VVSNNTLSKS SLMDMLTIEE NLQNDSIISK NLRTPNSPSE SIISPADIII
MGNITLNFEN KLTELLKNMS AEMKGLNFTV ALIPMRMMNS VMSDYRDIYE NATDIRDDAK
DIVLLMFSKP SSNETGMGKI EPLLQNLTYV LTQSNNFSVK SKVLTMLTPP LGNSTLGNES
MNPLFKYFVE DILSNMSLEN KSISVHYFSL TNTFTESSLD YSLSSINSAI DGNNQLINAL
NMVKGSIMSG DNATALYIMN KTIEGVSSNI AHMSFAYPYY YSFNNSLSKF LYDFKMGTLT
PQDVESLKEN TSAMLTISSG EFKNMLQILY DTLNQWTQSN YISYDLLYEA NSTLPAVQGF
LQNYQGAIML NNSLTSIKME INYAPVGNTT AHIEYLIGYL KNANAELEKQ KEFIENAMGA
MDTPYYRWYT QMLSDLDYVL YNSNVADYAM NIFVFTLQMM NEGAQGGNMG DFTIFYSLKH
AFDSNVAPKY KEEIQSMYLT IMGMMKIGKG YEGEMPSMPS SPSIKLPNLN PSYAEKKNIL
KNMSYEDITK TVSSIENYNA SEFMNTVNST IPIVENASAN MSSFANDIEK LVNNMEFVYS
TTGDYNVSNM LKMYTQLHAN ISAASNALDS LSSNLPHMSG FTYMMHRFSG QLKTMFSKDF
NGKTAKAAML IVMLNDTRLP GESDAQHSKR MEALEERVES IAKESDISSK VMVMGTYLIS
QATEKTSNET MNVIFPIAII LVIVILLITF RSIVDTLLGI LGLGMAISWA YGFGVIMNYN
FNQISTTVAV LLVGLGIDYA IHTILRYREE LRKGRKVRDA MNEMITHLGM GLILATITTI
IAFLSNVSSP IPPVSDFGIM NAVGIFGAFV IFTTAIPAMK ILIDERREKK GKLKIKKEKE
REGSGLIVLN KFMALSAMAA EHHRIAVIAA VLLISGVAIY GGMNVNTTFD LKDFLPQNLE
ITDTINFMMD HFNASGMSDN YVLIEGNITS PSALKAVQAT MQNLKDDDYV DYSQSSSITT
LISEWKEKNS TFAKMVSGND TNGDGLPDKN IKAIYDWLYE NANGKSILHK SNGTYDSMLI
IIRSSASNDK ENKILTKEID EDIQPLKDAG LKAIPTGTNL LTFHILDMLE GSQWRSLMIT
VIASLIVLTI VFLYEKRSWI LGLITSIPVV LALLWLLGSM YALGINFNVV TVTITSLTIG
LGITYAIHIT HRFLEDWERE KSIEDAVKKT VRHTGTSIFG AAATTMAGFG TLMLSSMPPI
QQFGEIAALS ILYSFVLSVF ILPTFLYMWA SWREKRNKL
//
