ID   B5IPG0_9CYAN            Unreviewed;       475 AA.
AC   B5IPG0;
DT   14-OCT-2008, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2008, sequence version 1.
DT   24-JAN-2024, entry version 70.
DE   RecName: Full=Aldehyde dehydrogenase {ECO:0000256|PIRNR:PIRNR036492};
GN   Name=alkH {ECO:0000313|EMBL:EDY37605.1};
GN   ORFNames=CPCC7001_484 {ECO:0000313|EMBL:EDY37605.1};
OS   Cyanobium sp. PCC 7001.
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Synechococcales;
OC   Prochlorococcaceae; Cyanobium.
OX   NCBI_TaxID=180281 {ECO:0000313|EMBL:EDY37605.1, ECO:0000313|Proteomes:UP000003950};
RN   [1] {ECO:0000313|EMBL:EDY37605.1, ECO:0000313|Proteomes:UP000003950}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 7001 {ECO:0000313|EMBL:EDY37605.1,
RC   ECO:0000313|Proteomes:UP000003950};
RA   Lily E., Ferriera S., Johnson J., Kravitz S., Beeson K., Sutton G.,
RA   Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL   Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC       {ECO:0000256|ARBA:ARBA00009986, ECO:0000256|PIRNR:PIRNR036492,
CC       ECO:0000256|RuleBase:RU003345}.
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DR   EMBL; DS990556; EDY37605.1; -; Genomic_DNA.
DR   AlphaFoldDB; B5IPG0; -.
DR   STRING; 180281.CPCC7001_484; -.
DR   eggNOG; COG1012; Bacteria.
DR   HOGENOM; CLU_005391_3_1_3; -.
DR   Proteomes; UP000003950; Unassembled WGS sequence.
DR   GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   GO; GO:0006081; P:cellular aldehyde metabolic process; IEA:InterPro.
DR   CDD; cd07087; ALDH_F3-13-14_CALDH-like; 1.
DR   InterPro; IPR016161; Ald_DH/histidinol_DH.
DR   InterPro; IPR016163; Ald_DH_C.
DR   InterPro; IPR029510; Ald_DH_CS_GLU.
DR   InterPro; IPR016162; Ald_DH_N.
DR   InterPro; IPR015590; Aldehyde_DH_dom.
DR   InterPro; IPR012394; Aldehyde_DH_NAD(P).
DR   PANTHER; PTHR43570; ALDEHYDE DEHYDROGENASE; 1.
DR   PANTHER; PTHR43570:SF16; ALDEHYDE DEHYDROGENASE TYPE III, ISOFORM Q; 1.
DR   Pfam; PF00171; Aldedh; 1.
DR   PIRSF; PIRSF036492; ALDH; 1.
DR   SUPFAM; SSF53720; ALDH-like; 1.
DR   PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE   3: Inferred from homology;
KW   NADP {ECO:0000256|ARBA:ARBA00022857};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000256|PIRNR:PIRNR036492};
KW   Reference proteome {ECO:0000313|Proteomes:UP000003950}.
FT   DOMAIN          32..447
FT                   /note="Aldehyde dehydrogenase"
FT                   /evidence="ECO:0000259|Pfam:PF00171"
FT   ACT_SITE        225
FT                   /evidence="ECO:0000256|PIRSR:PIRSR036492-1,
FT                   ECO:0000256|PROSITE-ProRule:PRU10007"
FT   ACT_SITE        259
FT                   /evidence="ECO:0000256|PIRSR:PIRSR036492-1"
SQ   SEQUENCE   475 AA;  51134 MW;  1A6E365105F48866 CRC64;
     MPASNPVTVD SPAAAPSALL SVPIAVMREP VSEGATRSLA WRLEQLERLG QLLDSQEQAI
     REALAADLGK PAMEAQFELV AVRQELRHTR RHLRRWMAPS RVPVDLPLRP GRAWVQPEPL
     GCVLIIGPWN YPAQLCLHPL VSALAAGNTV VLKPSEHAPR TAALLARAVA EHFPAAVVQV
     VTGDGATAAA LLENRFDHIL FTGGGRVGRL VMAAAARHLT PVTLELGGKS PAIVLADADL
     AVTARRLAWG KGLNAGQTCI APDHLLVEAP VRQALVEGLS QELTRFYGPD PLASPDLGTI
     VNEAQYARLA ELLEGARRRG QILHGGQCDP ERRRIAPTLL AVDDPDDPLM EDELFGPLLP
     VLTVEHLDGA IRQVRSRPKP LALYLFSRSS EARERVLNAT SSGSVCVNDV VMQAGVTALA
     FGGVGESGLG RYHGRAGFDT FSHRRSVLSR PFWLDLPVRY PPYAGKLGLV KRLLG
//