ID   B5JIQ2_9BACT            Unreviewed;       774 AA.
AC   B5JIQ2;
DT   14-OCT-2008, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2008, sequence version 1.
DT   27-MAR-2024, entry version 51.
DE   SubName: Full=Trypsin domain protein {ECO:0000313|EMBL:EDY83977.1};
GN   ORFNames=VDG1235_3604 {ECO:0000313|EMBL:EDY83977.1};
OS   Verrucomicrobiae bacterium DG1235.
OC   Bacteria; Verrucomicrobiota; Verrucomicrobiae.
OX   NCBI_TaxID=382464 {ECO:0000313|EMBL:EDY83977.1, ECO:0000313|Proteomes:UP000003839};
RN   [1] {ECO:0000313|EMBL:EDY83977.1, ECO:0000313|Proteomes:UP000003839}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DG1235 {ECO:0000313|EMBL:EDY83977.1,
RC   ECO:0000313|Proteomes:UP000003839};
RA   Hart M., Ferriera S., Johnson J., Kravitz S., Beeson K., Sutton G.,
RA   Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL   Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; DS990592; EDY83977.1; -; Genomic_DNA.
DR   AlphaFoldDB; B5JIQ2; -.
DR   STRING; 382464.VDG1235_3604; -.
DR   eggNOG; COG5640; Bacteria.
DR   HOGENOM; CLU_386818_0_0_0; -.
DR   OrthoDB; 9813836at2; -.
DR   Proteomes; UP000003839; Unassembled WGS sequence.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   CDD; cd00190; Tryp_SPc; 1.
DR   Gene3D; 2.40.10.10; Trypsin-like serine proteases; 1.
DR   InterPro; IPR009003; Peptidase_S1_PA.
DR   InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR   InterPro; IPR001314; Peptidase_S1A.
DR   InterPro; IPR001254; Trypsin_dom.
DR   InterPro; IPR018114; TRYPSIN_HIS.
DR   InterPro; IPR033116; TRYPSIN_SER.
DR   PANTHER; PTHR24256; TRYPTASE-RELATED; 1.
DR   PANTHER; PTHR24256:SF568; ZGC:123217; 1.
DR   Pfam; PF00089; Trypsin; 1.
DR   PRINTS; PR00722; CHYMOTRYPSIN.
DR   SMART; SM00020; Tryp_SPc; 1.
DR   SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR   PROSITE; PS50240; TRYPSIN_DOM; 1.
DR   PROSITE; PS00134; TRYPSIN_HIS; 1.
DR   PROSITE; PS00135; TRYPSIN_SER; 1.
PE   4: Predicted;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Hydrolase {ECO:0000256|RuleBase:RU363034};
KW   Protease {ECO:0000256|RuleBase:RU363034};
KW   Reference proteome {ECO:0000313|Proteomes:UP000003839};
KW   Serine protease {ECO:0000256|RuleBase:RU363034};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           25..774
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5002835544"
FT   DOMAIN          39..283
FT                   /note="Peptidase S1"
FT                   /evidence="ECO:0000259|PROSITE:PS50240"
SQ   SEQUENCE   774 AA;  85443 MW;  F515F89ECE4846AC CRC64;
     MYVALKRMLA WLCLGLCGTI ASLADDPSNQ SEDLITPSVI GGTNAPLNKY PWVVALVGRP
     GSVNGELHEK QFCTGVLIHP YWVLTAAHCV SDLQSYEYLA VAAGNGNLQE GSMNEHVVDL
     VVRHHYYAPE IDLEADVALV RLMEPVLDRA PIAINFDDDL DEDRDAGRIL GWGRTNNNFD
     APDQVKRLQE ASLPIPDRAL ANSAAHFNGA LSETMIAAGK GSPLTSGFVG DSGGPFVMEN
     VGPEDYVLLG ITSWGYTCDL DTTPYTVFGS VSQHTDWIDS VISPDNLELN EASLFAKYKE
     VETLENKVQP QPFAENGTLG FSLELPMNGR SDLRLEEGVQ DDRFGDPILS FSEVDAFSPL
     EDGWNFDYER GVLERKVKSS STETDQYFLR IEQEAGISPR PGPYPLSPGM LASGKRLAES
     SLFGDRTIWF ELLGHQAGDL ITFTGWSPGY IGMAIVECDG DQTRLAAKNF EQDGSYPWGT
     HLLDVRAKKG MRYYGIVHES NSFEVSCWVN LDRKEIRLNE PIFGTLGVSD MRTPRNGHFC
     EFFEMHDKSR QDLLVELYSD FDGTIELIEL ESGKVLSTAD DVNGSGTESL VFYHKDTDKS
     LGIRIMNTNS NEIGDYRIEF KRFSKPRGLR VGASSQSALM ESSESQYIEG QTVYIDDWDL
     EGLTAGRRTY VSVEGVGGHN PQFAILDVTG RETVFEGFSI CPDDSVASFV PASGRNYVLL
     IAGIEGDLNR NYKVTSSRNP IILSTNLEGE KVKRPMFPMN MQSVISNSGA MDPH
//