ID B5JQH2_9BACT Unreviewed; 267 AA.
AC B5JQH2;
DT 14-OCT-2008, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2008, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein {ECO:0000313|EMBL:EDY81061.1};
GN ORFNames=VDG1235_678 {ECO:0000313|EMBL:EDY81061.1};
OS Verrucomicrobiae bacterium DG1235.
OC Bacteria; Verrucomicrobiota; Verrucomicrobiae.
OX NCBI_TaxID=382464 {ECO:0000313|EMBL:EDY81061.1, ECO:0000313|Proteomes:UP000003839};
RN [1] {ECO:0000313|EMBL:EDY81061.1, ECO:0000313|Proteomes:UP000003839}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DG1235 {ECO:0000313|EMBL:EDY81061.1,
RC ECO:0000313|Proteomes:UP000003839};
RA Hart M., Ferriera S., Johnson J., Kravitz S., Beeson K., Sutton G.,
RA Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; DS990592; EDY81061.1; -; Genomic_DNA.
DR AlphaFoldDB; B5JQH2; -.
DR STRING; 382464.VDG1235_678; -.
DR eggNOG; COG0111; Bacteria.
DR HOGENOM; CLU_019796_1_3_0; -.
DR OrthoDB; 9805416at2; -.
DR Proteomes; UP000003839; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:UniProt.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR029753; D-isomer_DH_CS.
DR InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR10996:SF178; 2-HYDROXYACID DEHYDROGENASE YGL185C-RELATED; 1.
DR PANTHER; PTHR10996; 2-HYDROXYACID DEHYDROGENASE-RELATED; 1.
DR Pfam; PF02826; 2-Hacid_dh_C; 1.
DR SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00670; D_2_HYDROXYACID_DH_2; 1.
DR PROSITE; PS00671; D_2_HYDROXYACID_DH_3; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000003839}.
FT DOMAIN 105..246
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02826"
SQ SEQUENCE 267 AA; 29560 MW; 8C131354DA49FC8D CRC64;
MKFWKNTGTL DDLVSELKDC VHSAEAEVAV IGSKPISLAA MPKLRGLFKC GVGTDNVPFK
ECRDRDIRIG LPSAKTSSVI YEETASFAAS TVLRMLYSEV GDLETWEKYP REMARTRRVL
VVGLGNIGSR VVDKLKPTVE VIGYDAAFPD SGDLDGLIFE ADVVTLHIPL DEANRGFFDK
EKLAMMRDGA VLVNTARGPI VDEEALYDEL ISGRLRAAFD VFWQEPYRGK LAALHPDPFF
MTPHVASSCR DFVSGLANDF RVFCKSI
//
