ID B5PGF0_SALET Unreviewed; 591 AA.
AC B5PGF0;
DT 04-NOV-2008, integrated into UniProtKB/TrEMBL.
DT 04-NOV-2008, sequence version 1.
DT 01-MAY-2013, entry version 29.
DE RecName: Full=L-fucose isomerase;
DE EC=5.3.1.25;
DE AltName: Full=6-deoxy-L-galactose isomerase;
DE AltName: Full=FucIase;
GN Name=fucI; ORFNames=SeW_A3418;
OS Salmonella enterica subsp. enterica serovar Weltevreden str.
OS HI_N05-537.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=465518;
RN [1]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HI_N05-537;
RX PubMed=21602358; DOI=10.1128/JB.00297-11;
RA Fricke W.F., Mammel M.K., McDermott P.F., Tartera C., White D.G.,
RA Leclerc J.E., Ravel J., Cebula T.A.;
RT "Comparative genomics of 28 Salmonella enterica isolates: evidence for
RT CRISPR-mediated adaptive sublineage evolution.";
RL J. Bacteriol. 193:3556-3568(2011).
CC -!- FUNCTION: Converts the aldose L-fucose into the corresponding
CC ketose L-fuculose (By similarity).
CC -!- CATALYTIC ACTIVITY: L-fucose = L-fuculose.
CC -!- COFACTOR: Manganese (By similarity).
CC -!- PATHWAY: Carbohydrate degradation; L-fucose degradation; L-
CC lactaldehyde and glycerone phosphate from L-fucose: step 1/3.
CC -!- SUBUNIT: Homohexamer (By similarity).
CC -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC -!- SIMILARITY: Belongs to the L-fucose isomerase family.
CC -!- CAUTION: The sequence shown here is derived from an
CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC preliminary data.
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; ABFF01000007; EDZ29592.1; -; Genomic_DNA.
DR ProteinModelPortal; B5PGF0; -.
DR SMR; B5PGF0; 1-591.
DR PRIDE; B5PGF0; -.
DR EnsemblBacteria; EDZ29592; EDZ29592; SeW_A3418.
DR PATRIC; 25793460; VBISalEnt31937_2242.
DR UniPathway; UPA00563; UER00624.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008736; F:L-fucose isomerase activity; IEA:HAMAP.
DR GO; GO:0030145; F:manganese ion binding; IEA:HAMAP.
DR GO; GO:0019317; P:fucose catabolic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.20.14.10; -; 1.
DR Gene3D; 3.40.275.10; -; 1.
DR Gene3D; 3.40.50.1070; -; 1.
DR HAMAP; MF_01254; Fucose_iso; 1; -.
DR InterPro; IPR004216; Fuc/Ara_isomerase_C.
DR InterPro; IPR015888; Fuc_isomerase_C.
DR InterPro; IPR012888; Fucose_iso_N1.
DR InterPro; IPR005763; Fucose_isomerase.
DR InterPro; IPR009015; Fucose_isomerase_N/cen.
DR InterPro; IPR012889; Fucose_isomerase_N2.
DR Pfam; PF02952; Fucose_iso_C; 1.
DR Pfam; PF07881; Fucose_iso_N1; 1.
DR Pfam; PF07882; Fucose_iso_N2; 1.
DR SUPFAM; SSF50443; Fuc_isomerase_C; 1.
DR SUPFAM; SSF53743; Fuc_isomerase_N; 1.
DR TIGRFAMs; TIGR01089; fucI; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism; Cytoplasm; Fucose metabolism; Isomerase;
KW Manganese; Metal-binding.
FT ACT_SITE 337 337 Proton acceptor (By similarity).
FT ACT_SITE 361 361 Proton acceptor (By similarity).
FT METAL 337 337 Manganese (By similarity).
FT METAL 361 361 Manganese (By similarity).
FT METAL 528 528 Manganese (By similarity).
SQ SEQUENCE 591 AA; 64771 MW; 0A1C6439714D46AB CRC64;
MKKISLPKIG IRPVIDGRRM GVRESLEEQT MNMAKATAAL ITEKIRHACG AQVECVIADT
CIAGMAESAA CEEKFSSQNV GVTITVTPCW CYGSETIDMD PMRPKAIWGF NGTERPGAVY
LAAALAAHSQ KGIPAFSIYG HDVQDADDTS IPADVEEKLL RFARAGLAVA SMKGKSYLSV
GGVSMGIAGS IVDHNFFESW LGMKVQAVDM TELRRRIDQK IYDEAELEMA LAWADKNFRY
GEDQNASQYK RNEAQNRAVL KESLLMAMCI RDMMQGNKTL ADKGLVEESL GYNAIAAGFQ
GQRHWTDQYP NGDTAEALLN SSFDWNGVRE PFVVATENDS LNGVAMLFGH QLTGTAQIFA
DVRTYWSPEA VERVTGQALS GLAEHGIIHL INSGSAALDG ACKQRDSEGK PTMKPHWEIS
QQEADACLAA TEWCPAIHEY FRGGGYSSRF LTEGGVPFTM TRVNIIKGLG PVLQIAEGWS
VELPKAMHDQ LDARTNSTWP TTWFAPRLTG KGPFTDVYSV MANWGANHGV LTIGHVGADF
ITLAAMLRIP VCMHNVEEAK IYRPSAWAAH GMDIEGQDYR ACQNYGPLYK R
//
