ID B5RGI5_SALG2 Unreviewed; 258 AA.
AC B5RGI5;
DT 04-NOV-2008, integrated into UniProtKB/TrEMBL.
DT 04-NOV-2008, sequence version 1.
DT 27-MAR-2024, entry version 93.
DE SubName: Full=Putative L-lactate dehydrogenase operon regulator {ECO:0000313|EMBL:CAR39518.1};
GN Name=lctR {ECO:0000313|EMBL:CAR39518.1};
GN OrderedLocusNames=SG3738 {ECO:0000313|EMBL:CAR39518.1};
OS Salmonella gallinarum (strain 287/91 / NCTC 13346).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=550538 {ECO:0000313|EMBL:CAR39518.1, ECO:0000313|Proteomes:UP000008321};
RN [1] {ECO:0000313|EMBL:CAR39518.1, ECO:0000313|Proteomes:UP000008321}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=287/91 / NCTC 13346 {ECO:0000313|Proteomes:UP000008321};
RX PubMed=18583645; DOI=10.1101/gr.077404.108;
RA Thomson N.R., Clayton D.J., Windhorst D., Vernikos G., Davidson S.,
RA Churcher C., Quail M.A., Stevens M., Jones M.A., Watson M., Barron A.,
RA Layton A., Pickard D., Kingsley R.A., Bignell A., Clark L., Harris B.,
RA Ormond D., Abdellah Z., Brooks K., Cherevach I., Chillingworth T.,
RA Woodward J., Norberczak H., Lord A., Arrowsmith C., Jagels K., Moule S.,
RA Mungall K., Sanders M., Whitehead S., Chabalgoity J.A., Maskell D.,
RA Humphrey T., Roberts M., Barrow P.A., Dougan G., Parkhill J.;
RT "Comparative genome analysis of Salmonella enteritidis PT4 and Salmonella
RT gallinarum 287/91 provides insights into evolutionary and host adaptation
RT pathways.";
RL Genome Res. 18:1624-1637(2008).
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DR EMBL; AM933173; CAR39518.1; -; Genomic_DNA.
DR RefSeq; WP_000636696.1; NC_011274.1.
DR AlphaFoldDB; B5RGI5; -.
DR SMR; B5RGI5; -.
DR KEGG; seg:SG3738; -.
DR HOGENOM; CLU_017584_9_5_6; -.
DR Proteomes; UP000008321; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd07377; WHTH_GntR; 1.
DR Gene3D; 1.20.120.530; GntR ligand-binding domain-like; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011711; GntR_C.
DR InterPro; IPR008920; TF_FadR/GntR_C.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR43537:SF18; L-LACTATE DEHYDROGENASE OPERON REGULATORY PROTEIN-RELATED; 1.
DR PANTHER; PTHR43537; TRANSCRIPTIONAL REGULATOR, GNTR FAMILY; 1.
DR Pfam; PF07729; FCD; 1.
DR Pfam; PF00392; GntR; 1.
DR PRINTS; PR00035; HTHGNTR.
DR SMART; SM00895; FCD; 1.
DR SMART; SM00345; HTH_GNTR; 1.
DR SUPFAM; SSF48008; GntR ligand-binding domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 6..74
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
SQ SEQUENCE 258 AA; 29102 MW; A01D55540CBCD3BA CRC64;
MIVMPKRLSD EIASRVRALI EEQNLEAGMK LPAERQLALQ LGVSRNSLRE ALAKLVSEGV
LVSRRGGGTF VRWQHETWSE QNIVQPLKML MANDPDYSFD ILEARHAIEA STAWHAAMRA
TAADKEKIRL CFDATLSEDP DLASQADVRF HLAIAEASHN VVLLQTMRGF FDVLQSSVKQ
SRQRMYLVPP VFSKLTEQHQ AVMDAILDGN AEGARKAMMA HLSFVHTTIK RFDEDQARQA
RITRLPGDHN EMTRENKS
//
