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Database: UniProt
Entry: B5WD85_9BURK
LinkDB: B5WD85_9BURK
Original site: B5WD85_9BURK 
ID   B5WD85_9BURK            Unreviewed;       387 AA.
AC   B5WD85;
DT   25-NOV-2008, integrated into UniProtKB/TrEMBL.
DT   25-NOV-2008, sequence version 1.
DT   25-OCT-2017, entry version 60.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|RuleBase:RU000577};
DE   Flags: Fragment;
GN   ORFNames=BH160DRAFT_1036 {ECO:0000313|EMBL:EEA03739.1};
OS   Burkholderia sp. H160.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia.
OX   NCBI_TaxID=516466 {ECO:0000313|EMBL:EEA03739.1, ECO:0000313|Proteomes:UP000004534};
RN   [1] {ECO:0000313|EMBL:EEA03739.1, ECO:0000313|Proteomes:UP000004534}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=H160 {ECO:0000313|EMBL:EEA03739.1,
RC   ECO:0000313|Proteomes:UP000004534};
RX   PubMed=23209196; DOI=10.1128/JB.01756-12;
RA   Ormeno-Orrillo E., Rogel M.A., Chueire L.M., Tiedje J.M.,
RA   Martinez-Romero E., Hungria M.;
RT   "Genome Sequences of Burkholderia sp. Strains CCGE1002 and H160,
RT   Isolated from Legume Nodules in Mexico and Brazil.";
RL   J. Bacteriol. 194:6927-6927(2012).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|RuleBase:RU000577}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|SAAS:SAAS00747961}.
CC   -!- SIMILARITY: Belongs to the DnaA family.
CC       {ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EEA03739.1}.
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DR   EMBL; ABYL01000008; EEA03739.1; -; Genomic_DNA.
DR   RefSeq; WP_008918037.1; NZ_ABYL01000008.1.
DR   EnsemblBacteria; EEA03739; EEA03739; BH160DRAFT_1036.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000004534; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU000577,
KW   ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000004534};
KW   Cytoplasm {ECO:0000256|SAAS:SAAS00747973};
KW   DNA replication {ECO:0000256|RuleBase:RU004227,
KW   ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|RuleBase:RU000577,
KW   ECO:0000256|SAAS:SAAS00748008};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU000577,
KW   ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000004534}.
FT   DOMAIN       84    218       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      295    364       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NON_TER       1      1       {ECO:0000313|EMBL:EEA03739.1}.
SQ   SEQUENCE   387 AA;  43301 MW;  7503B0566FBDA5F6 CRC64;
     NARSAAEDAA DLDLPSLDAN EAAAGRRTWR PGQGAGAAGS GENDSMYERS KLNPVLTFDN
     FVTGKANQLA RAAAIQVADN PGISYNPLFL YGGVGLGKTH LIHAIGNQLL MDKPGARIRY
     IHAEQYVSDV VKAYQRKAFD DFKRYYHSLD LLLIDDIQFF SGKSRTQEEF FYAFEALVAN
     KAQVIITSDT YPKEISGIDD RLISRFDSGL TVAIEPPELE MRVAILMRKA QSEFVSLNED
     VAFFVAKHLR SNVRELEGAL RKILAYSKFH GREITIELTK EALKDLLTVQ NRQISVENIQ
     KTVADFYSIK VADMYSKKRP ANIARPRQIA MYLAKELTQK SLPEIGELFG GRDHTTVLHA
     VRKIADERSK DAQLNHELHV LEQTLKG
//
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