ID B5X2D0_SALSA Unreviewed; 215 AA.
AC B5X2D0;
DT 25-NOV-2008, integrated into UniProtKB/TrEMBL.
DT 25-NOV-2008, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE RecName: Full=Casein kinase II subunit beta {ECO:0000256|ARBA:ARBA00017775, ECO:0000256|RuleBase:RU361268};
DE Short=CK II beta {ECO:0000256|RuleBase:RU361268};
GN Name=CSK2B {ECO:0000313|EMBL:ACI33461.1};
GN Synonyms=LOC106570061 {ECO:0000313|RefSeq:XP_013997484.1,
GN ECO:0000313|RefSeq:XP_013997485.1, ECO:0000313|RefSeq:XP_013997486.1},
GN LOC106588218 {ECO:0000313|RefSeq:XP_014032467.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|EMBL:ACI33461.1};
RN [1] {ECO:0000313|EMBL:ACI33461.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Brain {ECO:0000313|EMBL:ACI33461.1}, and Thyroid
RC {ECO:0000313|EMBL:ACI68887.1};
RG cGRASP (B.F. Koop & W.S. Davidson);
RA Leong J., von Schalburg K., Cooper G., Moore R., Holt R., Davidson W.S.,
RA Koop B.F.;
RL Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ACI33461.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Brain {ECO:0000313|EMBL:ACI33461.1}, and Thyroid
RC {ECO:0000313|EMBL:ACI68887.1};
RX PubMed=20433749; DOI=10.1186/1471-2164-11-279;
RA Leong J.S., Jantzen S.G., von Schalburg K.R., Cooper G.A., Messmer A.M.,
RA Liao N.Y., Munro S., Moore R., Holt R.A., Jones S.J., Davidson W.S.,
RA Koop B.F.;
RT "Salmo salar and Esox lucius full-length cDNA sequences reveal changes in
RT evolutionary pressures on a post-tetraploidization genome.";
RL BMC Genomics 11:279-279(2010).
RN [3] {ECO:0000313|EMBL:ACI33461.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Brain {ECO:0000313|EMBL:ACI33461.1}, and Thyroid
RC {ECO:0000313|EMBL:ACI68887.1};
RG cGRASP (B.F. Koop & W.S. Davidson);
RL Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|RefSeq:XP_013997484.1, ECO:0000313|RefSeq:XP_013997485.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_013997484.1,
RC ECO:0000313|RefSeq:XP_013997485.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Regulatory subunit of casein kinase II/CK2. As part of the
CC kinase complex regulates the basal catalytic activity of the alpha
CC subunit a constitutively active serine/threonine-protein kinase that
CC phosphorylates a large number of substrates containing acidic residues
CC C-terminal to the phosphorylated serine or threonine. Participates in
CC Wnt signaling. {ECO:0000256|RuleBase:RU361268}.
CC -!- SUBUNIT: Tetramer of two alpha and two beta subunits.
CC {ECO:0000256|RuleBase:RU361268}.
CC -!- SIMILARITY: Belongs to the casein kinase 2 subunit beta family.
CC {ECO:0000256|ARBA:ARBA00006941, ECO:0000256|RuleBase:RU361268}.
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DR EMBL; BT045199; ACI33461.1; -; mRNA.
DR EMBL; BT049086; ACI68887.1; -; mRNA.
DR EMBL; BT059240; ACN10953.1; -; mRNA.
DR EMBL; BT059760; ACN11473.1; -; mRNA.
DR RefSeq; XP_013997484.1; XM_014142009.1.
DR RefSeq; XP_013997485.1; XM_014142010.1.
DR RefSeq; XP_013997486.1; XM_014142011.1.
DR RefSeq; XP_014032467.1; XM_014176992.1.
DR STRING; 8030.ENSSSAP00000098417; -.
DR PaxDb; 8030-ENSSSAP00000098417; -.
DR GeneID; 106570061; -.
DR GeneID; 106588218; -.
DR KEGG; sasa:106570061; -.
DR OMA; DADFGRC; -.
DR OrthoDB; 5485421at2759; -.
DR Proteomes; UP000087266; Chromosome ssa27.
DR Bgee; ENSSSAG00000073825; Expressed in sexually immature organism and 16 other cell types or tissues.
DR GO; GO:0005956; C:protein kinase CK2 complex; IEA:UniProtKB-UniRule.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0019887; F:protein kinase regulator activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 2.20.25.20; -; 1.
DR Gene3D; 1.10.1820.10; protein kinase ck2 holoenzyme, chain C, domain 1; 1.
DR InterPro; IPR016149; Casein_kin_II_reg-sub_N.
DR InterPro; IPR035991; Casein_kinase_II_beta-like.
DR InterPro; IPR000704; Casein_kinase_II_reg-sub.
DR PANTHER; PTHR11740; CASEIN KINASE II SUBUNIT BETA; 1.
DR PANTHER; PTHR11740:SF0; CASEIN KINASE II SUBUNIT BETA; 1.
DR Pfam; PF01214; CK_II_beta; 1.
DR PRINTS; PR00472; CASNKINASEII.
DR SMART; SM01085; CK_II_beta; 1.
DR SUPFAM; SSF57798; Casein kinase II beta subunit; 1.
DR PROSITE; PS01101; CK2_BETA; 1.
PE 2: Evidence at transcript level;
KW Kinase {ECO:0000313|EMBL:ACI33461.1, ECO:0000313|RefSeq:XP_013997484.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Transferase {ECO:0000313|EMBL:ACI33461.1,
KW ECO:0000313|RefSeq:XP_013997484.1}.
SQ SEQUENCE 215 AA; 24885 MW; E47F849699B0E0EC CRC64;
MSSSEEVSWI SWFCGLRGNE FFCEVDEDYI QDKFNLTGLN EQVPHYRQAL DMILDLEPDE
ELEDNPNQSD LIEQAAEMLY GLIHARYILT NRGIAQMLEK YQQGDFGYCP RVYCENQPML
PIGLSDIPGE AMVKLYCPKC MDVYTPKSSR HHHTDGAYFG TGFPHMLFMV HPEYRPKRPA
NQFVPRLYGF KIHPMAYQLQ LQAASSFKSP VKAIR
//
