ID B5X5C1_SALSA Unreviewed; 364 AA.
AC B5X5C1;
DT 25-NOV-2008, integrated into UniProtKB/TrEMBL.
DT 25-NOV-2008, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Di-N-acetylchitobiase {ECO:0000313|EMBL:ACI66041.1, ECO:0000313|RefSeq:NP_001134050.1};
GN Name=DIAC {ECO:0000313|EMBL:ACI66041.1};
GN Synonyms=diac {ECO:0000313|RefSeq:NP_001134050.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|EMBL:ACI66041.1};
RN [1] {ECO:0000313|EMBL:ACI66041.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Thymus {ECO:0000313|EMBL:ACI66041.1};
RG cGRASP (B.F. Koop & W.S. Davidson);
RA Leong J., von Schalburg K., Cooper G., Moore R., Holt R., Davidson W.S.,
RA Koop B.F.;
RL Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ACI66041.1, ECO:0000313|RefSeq:NP_001134050.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Thymus {ECO:0000313|EMBL:ACI66041.1};
RX PubMed=20433749; DOI=10.1186/1471-2164-11-279;
RA Leong J.S., Jantzen S.G., von Schalburg K.R., Cooper G.A., Messmer A.M.,
RA Liao N.Y., Munro S., Moore R., Holt R.A., Jones S.J., Davidson W.S.,
RA Koop B.F.;
RT "Salmo salar and Esox lucius full-length cDNA sequences reveal changes in
RT evolutionary pressures on a post-tetraploidization genome.";
RL BMC Genomics 11:279-279(2010).
RN [3] {ECO:0000313|EMBL:ACI66041.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Thymus {ECO:0000313|EMBL:ACI66041.1};
RG cGRASP (B.F. Koop & W.S. Davidson);
RL Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|RefSeq:NP_001134050.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Lysosome {ECO:0000256|ARBA:ARBA00004371}.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 18 family.
CC {ECO:0000256|ARBA:ARBA00009336, ECO:0000256|RuleBase:RU004453}.
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DR EMBL; BT046240; ACI66041.1; -; mRNA.
DR RefSeq; NP_001134050.1; NM_001140578.1.
DR STRING; 8030.ENSSSAP00000070259; -.
DR CAZy; GH18; Glycoside Hydrolase Family 18.
DR PaxDb; 8030-ENSSSAP00000070259; -.
DR GeneID; 100195549; -.
DR KEGG; sasa:100195549; -.
DR CTD; 1486; -.
DR OMA; KTYKWIM; -.
DR OrthoDB; 718898at2759; -.
DR Proteomes; UP000087266; Chromosome ssa10.
DR Bgee; ENSSSAG00000063116; Expressed in liver and 16 other cell types or tissues.
DR GO; GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.
DR GO; GO:0008061; F:chitin binding; IEA:InterPro.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd02875; GH18_chitobiase; 1.
DR Gene3D; 3.10.50.10; -; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR011583; Chitinase_II.
DR InterPro; IPR029070; Chitinase_insertion_sf.
DR InterPro; IPR047898; DIAC_cat.
DR InterPro; IPR001223; Glyco_hydro18_cat.
DR InterPro; IPR001579; Glyco_hydro_18_chit_AS.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR46290; DI-N-ACETYLCHITOBIASE; 1.
DR PANTHER; PTHR46290:SF1; DI-N-ACETYLCHITOBIASE; 1.
DR Pfam; PF00704; Glyco_hydro_18; 1.
DR SMART; SM00636; Glyco_18; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR PROSITE; PS01095; GH18_1; 1.
DR PROSITE; PS51910; GH18_2; 1.
PE 2: Evidence at transcript level;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Signal {ECO:0000256|SAM:SignalP, ECO:0000313|RefSeq:NP_001134050.1}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..364
FT /evidence="ECO:0000256|SAM:SignalP,
FT ECO:0000313|RefSeq:NP_001134050.1"
FT /id="PRO_5009732148"
FT DOMAIN 1..363
FT /note="GH18"
FT /evidence="ECO:0000259|PROSITE:PS51910"
SQ SEQUENCE 364 AA; 41320 MW; 58F33ED6A5A80C4C CRC64;
MWLFLFLTLV SVCCKAEVCP CEIQELCQQI RDEKDFEVFV FDVGKKAWKS YDWGKVTTVA
AFGKYDAELM CHAHSKGVRL VLKGDVSILE MVDPANRTAW ITSKVDLAKR QFMDGINIDI
EQEVADSSPE YYTLTALVKE TTEAFHREIP GSQVSFDVAW SPKCIDRRCY DYAAIAESCD
LLFVMSYDEQ SQIWGDCVAM ANAPFNQTQS AYDQYLAMKI DPKKLVMGVP WYGYDYPCLD
FSQEGVCSLA KVPFRGAPCS DAAGRQIPYS FMMKQINGSL SGRLWDEVQL APYYNYKDQK
GQIHQVWYDD PESIALKVAY VRELGLKGTG MWCGNLLDYS NNPVAQEQSR DMWNALMGCQ
DAQC
//
