ID B5XTM8_KLEP3 Unreviewed; 507 AA.
AC B5XTM8;
DT 25-NOV-2008, integrated into UniProtKB/TrEMBL.
DT 25-NOV-2008, sequence version 1.
DT 27-MAR-2024, entry version 90.
DE SubName: Full=Transcriptional regulator, GntR family/aminotransferase family protein {ECO:0000313|EMBL:ACI06980.1};
GN OrderedLocusNames=KPK_0287 {ECO:0000313|EMBL:ACI06980.1};
OS Klebsiella pneumoniae (strain 342).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX NCBI_TaxID=507522 {ECO:0000313|EMBL:ACI06980.1, ECO:0000313|Proteomes:UP000001734};
RN [1] {ECO:0000313|EMBL:ACI06980.1, ECO:0000313|Proteomes:UP000001734}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=342 {ECO:0000313|EMBL:ACI06980.1,
RC ECO:0000313|Proteomes:UP000001734};
RX PubMed=18654632; DOI=10.1371/journal.pgen.1000141;
RA Fouts D.E., Tyler H.L., DeBoy R.T., Daugherty S., Ren Q., Badger J.H.,
RA Durkin A.S., Huot H., Shrivastava S., Kothari S., Dodson R.J., Mohamoud Y.,
RA Khouri H., Roesch L.F., Krogfelt K.A., Struve C., Triplett E.W.,
RA Methe B.A.;
RT "Complete genome sequence of the N2-fixing broad host range endophyte
RT Klebsiella pneumoniae 342 and virulence predictions verified in mice.";
RL PLoS Genet. 4:E1000141-E1000141(2008).
CC -!- SIMILARITY: In the C-terminal section; belongs to the class-I
CC pyridoxal-phosphate-dependent aminotransferase family.
CC {ECO:0000256|ARBA:ARBA00005384}.
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DR EMBL; CP000964; ACI06980.1; -; Genomic_DNA.
DR AlphaFoldDB; B5XTM8; -.
DR KEGG; kpe:KPK_0287; -.
DR HOGENOM; CLU_017584_0_1_6; -.
DR BioCyc; KPNE507522:GI0B-287-MONOMER; -.
DR Proteomes; UP000001734; Chromosome.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00609; AAT_like; 1.
DR CDD; cd07377; WHTH_GntR; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR004839; Aminotransferase_I/II.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR46577; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR PANTHER; PTHR46577:SF1; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR Pfam; PF00155; Aminotran_1_2; 1.
DR Pfam; PF00392; GntR; 1.
DR PRINTS; PR00035; HTHGNTR.
DR SMART; SM00345; HTH_GNTR; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
PE 3: Inferred from homology;
KW Aminotransferase {ECO:0000313|EMBL:ACI06980.1};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transferase {ECO:0000313|EMBL:ACI06980.1}.
FT DOMAIN 19..87
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
SQ SEQUENCE 507 AA; 56449 MW; BAED2DB4B8021789 CRC64;
MRSLVGDLVL VRLQKERDPL LHKRLYNALR RAILDGSLAP QSRLPPSRDL AGELGVSRNT
ILTTYEQLLA EGYVVSRRGS GTFVAQTAPE SSLTAKGQQE NSSIAAPTVH LSRRGQHLLG
QVSASPRQWG AFIPGVPDVN AFPHPLFSKI QARISRRPKP ERLSYSCNGG TPELQQALVD
YLRVSRGVHC QADQILITEG IHQAIDLVTR MLCDNGDLAW VEEPSYWGIR HVLAMNDVRV
EPLTVDANGL CPPETVDDAP RLIFVTPSHQ YPLGAVMSLE RRQRLLALAR QQGSWIVEDD
YDSEFRFSGQ PIPALQGLVP DAPVVYIGTF SKTLYPGLRL GYVVIPRPLV SDLKHAHAEL
YRGGHSLIQM ALAEFITAGH YSAHIRRMRL LYSRRRAFLT ELIQRHCMPY ALSDFSDNAG
LHLILNLPTE ADDVAIAKEA NARHILVRPL SRYYLTAARK KGLLMGFASQ PEEQMAPAFS
VLLDCLQTHC PQMLLPREDA EKQNAPT
//
