ID B5ZAC6_HELPG Unreviewed; 859 AA.
AC B5ZAC6;
DT 25-NOV-2008, integrated into UniProtKB/TrEMBL.
DT 25-NOV-2008, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE SubName: Full=Cell division protein {ECO:0000313|EMBL:ACI27106.1};
GN Name=ftsK {ECO:0000313|EMBL:ACI27106.1};
GN OrderedLocusNames=HPG27_340 {ECO:0000313|EMBL:ACI27106.1};
OS Helicobacter pylori (strain G27).
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=563041 {ECO:0000313|EMBL:ACI27106.1, ECO:0000313|Proteomes:UP000001735};
RN [1] {ECO:0000313|EMBL:ACI27106.1, ECO:0000313|Proteomes:UP000001735}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=G27 {ECO:0000313|EMBL:ACI27106.1,
RC ECO:0000313|Proteomes:UP000001735};
RX PubMed=18952803; DOI=10.1128/JB.01416-08;
RA Baltrus D.A., Amieva M.R., Covacci A., Lowe T.M., Merrell D.S.,
RA Ottemann K.M., Stein M., Salama N.R., Guillemin K.;
RT "The complete genome sequence of Helicobacter pylori strain G27.";
RL J. Bacteriol. 191:447-448(2009).
CC -!- SIMILARITY: Belongs to the FtsK/SpoIIIE/SftA family.
CC {ECO:0000256|ARBA:ARBA00006474}.
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DR EMBL; CP001173; ACI27106.1; -; Genomic_DNA.
DR RefSeq; WP_000837277.1; NC_011333.1.
DR AlphaFoldDB; B5ZAC6; -.
DR KEGG; hpg:HPG27_340; -.
DR HOGENOM; CLU_001981_4_0_7; -.
DR Proteomes; UP000001735; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR CDD; cd01127; TrwB_TraG_TraD_VirD4; 1.
DR Gene3D; 3.30.980.40; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR041027; FtsK_alpha.
DR InterPro; IPR002543; FtsK_dom.
DR InterPro; IPR018541; Ftsk_gamma.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR22683:SF41; DNA TRANSLOCASE FTSK; 1.
DR PANTHER; PTHR22683; SPORULATION PROTEIN RELATED; 1.
DR Pfam; PF17854; FtsK_alpha; 1.
DR Pfam; PF09397; FtsK_gamma; 1.
DR Pfam; PF01580; FtsK_SpoIIIE; 1.
DR SMART; SM00843; Ftsk_gamma; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50901; FTSK; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Cell cycle {ECO:0000313|EMBL:ACI27106.1};
KW Cell division {ECO:0000313|EMBL:ACI27106.1};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 45..67
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 117..135
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 533..723
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT REGION 172..210
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 235..371
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 178..210
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 309..354
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 550..557
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
SQ SEQUENCE 859 AA; 96580 MW; 59E9410A99B6C133 CRC64;
MKSKKLYLAL IIGVLLAFLT LSSWLGNSGL VGRFGVWFAA LNKKYFGYLS FINLPYLAWV
LFLLYKTKNP FTEIVLEKTL GHLLGILSLL FLQSSLLNQG EIGNSVRLFL RPFIGGFGLY
ALIMLMVVIS YLILFKLPPK SVFYPYINKT QSLLKEIYKQ CLQAFSPNFS PKKEGFENTP
PDIQKKETNN DKEKENLKEN PIDENHKTPN EESFLAIPTP YNTTLNDLKP QEGLVQISSH
PPTHYTIYPK RNRFDDLTNP TLKKTQQETK EREPTLTKET LTPTTPKPAT LKPIMPISAP
NTENHDKTQN PKTPNHPIKE DDLQESPQEN PQKENQKENI EEKENLKEEE KEIQNAPSFS
PLTPTSAKKP VMVKELSENK EILDELDYGE VQKPKDYELP TTQLLNTVCL KDTSLDENEI
DQKIQDLLSK LRTFKIDGDI IRTYSGPIVT TFEFRPAPNV KVSRILGLSD DLAMTLCAES
IRIQAPIKGK DVVGIEIPNS QSQIIYLREI LESELFQKSS SPLTLALGKD IVGNPFITDL
KKLPHLLIAG TTGSGKSVGV NAMILSLLYK NPPDQLKLVM IDPKMVEFSI YADIPHLLTP
IITDPKKAIG ALQSVAKEME RRYSLMSEYK VKTIDSYNEQ APNNGVEAFP YLIVVIDELA
DLMMTGGKEA EFPIARIAQM GRASGLHLIV ATQRPSVDVV TGLIKTNLPS RVSFRVGTKI
DSKVILDTDG AQSLLGRGDM LFTPPGTNGL VRLHAPFATE DEIKKIVDFI KAQKEVEYDK
DFLLEESRMP LDTPNYQGDD ILERAKAVIL EKKITSTSFL QRQLKIGYNQ AATITDELEA
QGFLSPRNAK GNREILQNF
//
