ID B6AF81_CRYMR Unreviewed; 403 AA.
AC B6AF81;
DT 25-NOV-2008, integrated into UniProtKB/TrEMBL.
DT 25-NOV-2008, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=acid phosphatase {ECO:0000256|ARBA:ARBA00012646};
DE EC=3.1.3.2 {ECO:0000256|ARBA:ARBA00012646};
GN ORFNames=CMU_032570 {ECO:0000313|EMBL:EEA06872.1};
OS Cryptosporidium muris (strain RN66).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Cryptosporidiidae; Cryptosporidium.
OX NCBI_TaxID=441375 {ECO:0000313|Proteomes:UP000001460};
RN [1] {ECO:0000313|EMBL:EEA06872.1, ECO:0000313|Proteomes:UP000001460}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RN66 {ECO:0000313|EMBL:EEA06872.1,
RC ECO:0000313|Proteomes:UP000001460};
RA Lorenzi H., Inman J., Miller J., Schobel S., Amedeo P., Caler E.V.,
RA da Silva J.;
RL Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a phosphate monoester + H2O = an alcohol + phosphate;
CC Xref=Rhea:RHEA:15017, ChEBI:CHEBI:15377, ChEBI:CHEBI:30879,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:67140; EC=3.1.3.2;
CC Evidence={ECO:0000256|ARBA:ARBA00000032};
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DR EMBL; DS989731; EEA06872.1; -; Genomic_DNA.
DR RefSeq; XP_002141221.1; XM_002141185.1.
DR AlphaFoldDB; B6AF81; -.
DR STRING; 441375.B6AF81; -.
DR EnsemblProtists; EEA06872; EEA06872; CMU_032570.
DR GeneID; 6996422; -.
DR VEuPathDB; CryptoDB:CMU_032570; -.
DR eggNOG; KOG2679; Eukaryota.
DR OMA; HTYDSTK; -.
DR OrthoDB; 203742at2759; -.
DR Proteomes; UP000001460; Unassembled WGS sequence.
DR GO; GO:0003993; F:acid phosphatase activity; IEA:UniProtKB-EC.
DR CDD; cd07378; MPP_ACP5; 1.
DR Gene3D; 3.60.21.10; -; 1.
DR InterPro; IPR024927; Acid_PPase.
DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR PANTHER; PTHR10161; TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5; 1.
DR PANTHER; PTHR10161:SF14; TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5; 1.
DR Pfam; PF00149; Metallophos; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:EEA06872.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001460};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..403
FT /note="acid phosphatase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002840079"
FT DOMAIN 23..294
FT /note="Calcineurin-like phosphoesterase"
FT /evidence="ECO:0000259|Pfam:PF00149"
SQ SEQUENCE 403 AA; 46902 MW; F978CB3CBE8B6AF7 CRC64;
MVMIWMILLL FPFIKCQLTT FNIADWGKVN KCQSDVIKGM LKLCDTLNPQ FIIAAGDNFY
ESGVDSINDT NWERILEKPF SKLPSNLKLH SCLGDHDWRK NPKAQVDYTN SPLNKRWKMN
GYWWYEVIDF KSSSKFSDII KAAGLKYDDQ LHIRKESINL RSNLTNNNFS DFIYLNNTKS
YINETHIKIF EGNSKINSSS KEDVTAVFIY LDSWVLARDS FKKTPKNFWY LQLNFLERVL
RACISKQVDW IIIVNHYSLY SSGIMHGPHI KLRSILLPLL KKYKVDLFIS GHDHHIELIE
PEDHTTQYHI VGGGCCPREG FCEIDKDSIY RLDSCGFGTL TLGKSIAISR YFNKYLNLFN
SVQYSSKELR DLMDIENEEF PPQEASEQIR QPLIRISGWG ILI
//
