ID B6AII5_CRYMR Unreviewed; 1073 AA.
AC B6AII5;
DT 25-NOV-2008, integrated into UniProtKB/TrEMBL.
DT 25-NOV-2008, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Peptidase M16 inactive domain-containing protein {ECO:0000313|EMBL:EEA08026.1};
DE EC=3.4.24.56 {ECO:0000313|EMBL:EEA08026.1};
GN ORFNames=CMU_031670 {ECO:0000313|EMBL:EEA08026.1};
OS Cryptosporidium muris (strain RN66).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Cryptosporidiidae; Cryptosporidium.
OX NCBI_TaxID=441375 {ECO:0000313|Proteomes:UP000001460};
RN [1] {ECO:0000313|EMBL:EEA08026.1, ECO:0000313|Proteomes:UP000001460}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RN66 {ECO:0000313|EMBL:EEA08026.1,
RC ECO:0000313|Proteomes:UP000001460};
RA Lorenzi H., Inman J., Miller J., Schobel S., Amedeo P., Caler E.V.,
RA da Silva J.;
RL Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase M16 family.
CC {ECO:0000256|ARBA:ARBA00007261}.
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DR EMBL; DS989736; EEA08026.1; -; Genomic_DNA.
DR RefSeq; XP_002142375.1; XM_002142339.1.
DR AlphaFoldDB; B6AII5; -.
DR STRING; 441375.B6AII5; -.
DR EnsemblProtists; EEA08026; EEA08026; CMU_031670.
DR GeneID; 6997464; -.
DR VEuPathDB; CryptoDB:CMU_031670; -.
DR eggNOG; KOG0959; Eukaryota.
DR OMA; RIMTHVI; -.
DR OrthoDB; 198750at2759; -.
DR Proteomes; UP000001460; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:UniProtKB-EC.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 4.
DR InterPro; IPR011249; Metalloenz_LuxS/M16.
DR InterPro; IPR011765; Pept_M16_N.
DR InterPro; IPR007863; Peptidase_M16_C.
DR PANTHER; PTHR43690:SF18; INSULIN-DEGRADING ENZYME-RELATED; 1.
DR PANTHER; PTHR43690; NARDILYSIN; 1.
DR Pfam; PF00675; Peptidase_M16; 1.
DR Pfam; PF05193; Peptidase_M16_C; 1.
DR SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 3.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:EEA08026.1};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000001460};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 33..138
FT /note="Peptidase M16 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00675"
FT DOMAIN 193..339
FT /note="Peptidase M16 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05193"
SQ SEQUENCE 1073 AA; 125565 MW; 01B72A270B3C243E CRC64;
MGSQNNIIKD EEFIKPITEY RKFRYYELNN KIKVFLIHDS NAVYSNLALS ISVGKFMGFY
NNINLPSFLL YGLFMGSRKF PSIHEFDNFL SSHGGEIEKE ITDRNSYYYL GIPSNYLNLA
LKRFSEFFKT PLFDRNGLIN QLRRFSQIFR DYYPGNLLNT SELIHEISYL NSLNKINCSS
REFDINNEYE YIRNEIIKFF REYYSADLMT LIIIDSKPFN ILEKYVSEFF LNIQNNNKIL
STFHISDKNV EPLLIYIGKI IHVKYNNPIN KIKLIFPITY KVSNDKLLSF QYIIDTLGHR
MKGSLVEFLK QRCWIEDLSL FVSSSEFGYS FIEISIDLTY IGINYLAYIL KSIYASINIL
KNKAINPDII DDRIKIEEIN FYYRESLNNK ELIYTIIENY SSHRYLPNEV LIGNVTIDKA
DTKDIQEAIK ILNPKNMILI IFSQNFVLTG MNMLLNNVEF MNELKLNMDN KFYNSLINDI
ENSDIRFDDL KYKEIKYHIE KLHPLFLNYL DKVDNVIQNT TFYYDLPDKN ECIPSLIEDY
TSNIMYQQYP IPLKDAINRY LNENYSEGCR VKLSMISPSF ENIFYFPILG STNVKTSLSF
RIMTHVISKS SLILPKALES TSRLLSTLNI LYRAIEIEIS SIIYSVTQAG NNVKLLVTKE
SEFGGSPFGL EILLLGYYPS LIIFIENFFT TLSNLNKIAE LSFQQAKFNY QNYLKFQIYE
TTSIEQSLNA LSDITLMQNM SYKLLMKQCS KIKLEDVIEL ANYIAQYGEI EGLIVGNLDP
IRAHKLINNI LKWLKHNEEK YHVSSKIDIT KSIKIARSTT LEGTRDSIEY YETLDLLSLV
NSNRNTYYYQ LNKNINDKRS HVLLFLGMGA ADYVSLVLLN MLKRIMSRIS QSGDNSELKL
DINVTIRFHV IGSSFAGLLF YAESTNRNIK FLTENILKFY RTFFESDNSI SLSDFEEARK
QYLHQLHFKP TKLVDISNEF YSQLVNRQIK FNTKISKILY LQNLNYEKLN SFSSAMRNSP
KVIIATQSQI GTNLDELCKY SPIRFQKITS KDELFYIEGI RTYKFPLKMS DKY
//
