ID B6AMB1_9BACT Unreviewed; 702 AA.
AC B6AMB1;
DT 25-NOV-2008, integrated into UniProtKB/TrEMBL.
DT 25-NOV-2008, sequence version 1.
DT 13-SEP-2023, entry version 37.
DE RecName: Full=Flagellar biosynthesis protein FlhA {ECO:0000256|RuleBase:RU364093};
GN Name=flhA {ECO:0000256|RuleBase:RU364093};
GN ORFNames=CGL2_11277254 {ECO:0000313|EMBL:EDZ39618.1};
OS Leptospirillum sp. Group II '5-way CG'.
OC Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
OC Leptospirillum.
OX NCBI_TaxID=419541 {ECO:0000313|EMBL:EDZ39618.1};
RN [1] {ECO:0000313|EMBL:EDZ39618.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=14961025; DOI=10.1038/nature02340;
RA Tyson G.W., Chapman J., Hugenholtz P., Allen E.E., Ram R.J.,
RA Richardson P.M., Solovyev V.V., Rubin E.M., Rokhsar D.S., Banfield J.F.;
RT "Community structure and metabolism through reconstruction of microbial
RT genomes from the environment.";
RL Nature 428:37-43(2004).
RN [2] {ECO:0000313|EMBL:EDZ39618.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=18651792; DOI=10.1371/journal.pbio.0060177;
RA Simmons S.L., Dibartolo G., Denef V.J., Goltsman D.S., Thelen M.P.,
RA Banfield J.F.;
RT "Population genomic analysis of strain variation in Leptospirillum group II
RT bacteria involved in acid mine drainage formation.";
RL PLoS Biol. 6:E177-E177(2008).
CC -!- FUNCTION: Required for formation of the rod structure of the flagellar
CC apparatus. Together with FliI and FliH, may constitute the export
CC apparatus of flagellin. {ECO:0000256|RuleBase:RU364093}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU364093};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU364093}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FHIPEP (flagella/HR/invasion proteins export
CC pore) family. {ECO:0000256|ARBA:ARBA00008835,
CC ECO:0000256|RuleBase:RU364093}.
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DR EMBL; DS995259; EDZ39618.1; -; Genomic_DNA.
DR AlphaFoldDB; B6AMB1; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR Gene3D; 3.40.30.60; FHIPEP family, domain 1; 1.
DR Gene3D; 1.10.8.540; FHIPEP family, domain 3; 1.
DR Gene3D; 3.40.50.12790; FHIPEP family, domain 4; 1.
DR InterPro; IPR042194; FHIPEP_1.
DR InterPro; IPR042193; FHIPEP_3.
DR InterPro; IPR042196; FHIPEP_4.
DR InterPro; IPR025505; FHIPEP_CS.
DR InterPro; IPR006301; FlhA.
DR InterPro; IPR001712; T3SS_FHIPEP.
DR NCBIfam; TIGR01398; FlhA; 1.
DR PANTHER; PTHR30161:SF1; FLAGELLAR BIOSYNTHESIS PROTEIN FLHA-RELATED; 1.
DR PANTHER; PTHR30161; FLAGELLAR EXPORT PROTEIN, MEMBRANE FLHA SUBUNIT-RELATED; 1.
DR Pfam; PF00771; FHIPEP; 1.
DR PIRSF; PIRSF005419; FlhA; 1.
DR PRINTS; PR00949; TYPE3IMAPROT.
DR PROSITE; PS00994; FHIPEP; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum biogenesis {ECO:0000256|RuleBase:RU364093};
KW Bacterial flagellum protein export {ECO:0000256|RuleBase:RU364093};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU364093};
KW Cell projection {ECO:0000313|EMBL:EDZ39618.1};
KW Cilium {ECO:0000313|EMBL:EDZ39618.1};
KW Flagellum {ECO:0000313|EMBL:EDZ39618.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU364093};
KW Protein transport {ECO:0000256|RuleBase:RU364093};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU364093};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU364093}; Transport {ECO:0000256|RuleBase:RU364093}.
FT TRANSMEM 21..41
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 47..66
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 78..98
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 118..141
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 210..231
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 251..272
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 293..326
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
SQ SEQUENCE 702 AA; 75911 MW; 7EE98E100905F514 CRC64;
MASTKDSRNT SVWPAILDSR SDILILVGVV GILFIMIVPM PPLLLDLFLA TNITFSLVIL
LVAMTTKNLL EFTIFPSILL LSTLFRLSLN VASTRLILLH GQNGTGAAGH VIQSFGRFVV
GGSYAVGLVL FAIFVVINFV VVTRGAGRIA EVAARFTLDA LPGKQMAIDA DLNSGAIKEE
EARKRRKELS RESEFYGAMD GASKFVRGDA VAAILILFVN ILGGLVIGMV LKGLDLPEAL
HNYTLLTIGE GLVAQLPALI VSVAAGIVVT RAGSGNDLGS EIREQVLTRP RPLGGASGIL
FLLSVIPGLP HAAFFLLASV TGLMAYRRTT LEKKKARELQ AEEKTVPPPA ENVETYLSLD
LLELNVGYGL VDLVEGKAGS NLTDRIRGIR RQLAQEMGII VPPIHIRDNL QLKPDEYVVL
LKGAPVARWE LLPDSLLAMN PGMEPVTVEG IPVKEPTFGL PATWIAPDAR EEVEAQGFTV
VDPLTVLSTH LTEVIRSHAA ELVGRQEVQR LLDALGKDYP RLVEDLVPGQ VSLGVLVSVL
HALLSERVSI RDLRTILEAV SDQIAAGRDS KDVTGLAEGV RQALGRSIVN PYLAGKARSL
PVVTFDRRWE EVFMKQASQT PPGSPLVLEP GLAQKLLSGL GQVMESLGRK GVQPVLLVSA
QTRVPVRRFL ERYFSSLPVL SPMEVPKDVP IVSQEVVRFQ EE
//
