ID B6B0G5_9RHOB Unreviewed; 938 AA.
AC B6B0G5;
DT 25-NOV-2008, integrated into UniProtKB/TrEMBL.
DT 25-NOV-2008, sequence version 1.
DT 24-JAN-2024, entry version 59.
DE SubName: Full=Bifunctional hemolysin-adenylate cyclase (Cyclolysin) (ACT)(AC-HLY) {ECO:0000313|EMBL:EDZ43909.1};
DE EC=4.6.1.1 {ECO:0000313|EMBL:EDZ43909.1};
GN ORFNames=RB2083_3424 {ECO:0000313|EMBL:EDZ43909.1};
OS Rhodobacteraceae bacterium HTCC2083.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae.
OX NCBI_TaxID=314270 {ECO:0000313|EMBL:EDZ43909.1, ECO:0000313|Proteomes:UP000005746};
RN [1] {ECO:0000313|Proteomes:UP000005746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HTCC2083 {ECO:0000313|Proteomes:UP000005746};
RX PubMed=21036993; DOI=10.1128/JB.01268-10;
RA Kang I., Vergin K.L., Oh H.M., Choi A., Giovannoni S.J., Cho J.C.;
RT "Genome sequence of strain HTCC2083, a novel member of the marine clade
RT Roseobacter.";
RL J. Bacteriol. 193:319-320(2011).
CC -!- COFACTOR:
CC Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC Evidence={ECO:0000256|ARBA:ARBA00001913};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; DS995276; EDZ43909.1; -; Genomic_DNA.
DR AlphaFoldDB; B6B0G5; -.
DR STRING; 314270.RB2083_3424; -.
DR eggNOG; COG2931; Bacteria.
DR HOGENOM; CLU_312574_0_0_5; -.
DR OrthoDB; 7667870at2; -.
DR Proteomes; UP000005746; Unassembled WGS sequence.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProtKB-EC.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR Gene3D; 2.150.10.10; Serralysin-like metalloprotease, C-terminal; 6.
DR InterPro; IPR018511; Hemolysin-typ_Ca-bd_CS.
DR InterPro; IPR001343; Hemolysn_Ca-bd.
DR InterPro; IPR013858; Peptidase_M10B_C.
DR InterPro; IPR011049; Serralysin-like_metalloprot_C.
DR PANTHER; PTHR38340; S-LAYER PROTEIN; 1.
DR PANTHER; PTHR38340:SF1; S-LAYER PROTEIN; 1.
DR Pfam; PF00353; HemolysinCabind; 10.
DR Pfam; PF08548; Peptidase_M10_C; 1.
DR PRINTS; PR00313; CABNDNGRPT.
DR SUPFAM; SSF51120; beta-Roll; 4.
DR PROSITE; PS00330; HEMOLYSIN_CALCIUM; 3.
PE 4: Predicted;
KW Lyase {ECO:0000313|EMBL:EDZ43909.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000005746};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 814..937
FT /note="Peptidase M10 serralysin C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08548"
FT REGION 296..315
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 938 AA; 95241 MW; 995A70FEF444C4FB CRC64;
MTVTPTGEYI FDAPAPIVLP EPEPVDPDPV PFGTLFSLSG DDAIVLQIDE TTGAITLNDW
LTPDPGDNWD ADEDGIYDFN IVTTAPDGTV VTTAATLTQD TEGTFMVNAP TIDILPEDTG
PVDPPVTGTE LITNGLLEGG VAFENNDSDG DVDGWATSSG TVDVWGDGFF GVNTPDGGNF
IQVDTGADGS IDTVYQDVRT LEDDQMELEF SAAQRFGESE SLEVYYRDEL IDTVTPTSSE
EWDTYTVTGS GGLDRLEFRE LASESDGSGP FVDNVSLISA SPDAPALALR PNLTEDVLDS
PGLPTRPTAE PEPEGVPGLA LVATDAGGTL TGTAGDDTLS GGAGTDVLNG LAGNDVFVAS
AGPDTVDGGA GADVYDINSS VLSVNDINVD LAEGNAGATT LLNVESVFGG SGANLLSGNA
QDNLLSGGDG DDTLFGLDGD DVLIGGLGND THVGAQGDDI LIMNEGANFF VGGLGEDALV
INSSTLESSA FAIDLAAGTD QYGNTYNTIE NIDGGLGDDN FAGTDDANVL IGRAGDDTLS
GRLGGDVLSG GAGDDVHNGG GGEDLLIASA GADTFNGGAG IDTYDIDISD DYEADYGVNL
ATGVDNLGNS YSGIENVNGG WGDDSLTGDA GINILDGGVG DDVVMGGAGD DSLAGGLVND
VLDGGDDNDV LFGSFGVDTY EGGAGVDTFD IGGSTAGEAD YNIDLTVGQD QYGNTYSNIE
NVTTGSGDDN LFGNAADNQL QGNDGDDTID GAAGNDFHNG GNGDDVFLAN AGSNSYFGGN
GVDTLQIVGT TEDAVSYSIN LAEGIDDQGN TNFGVENVNA GSGNDRLVGN FDDNALYGGV
GDDTLTGGGG DDTLTGGLGD DVFTMGNDAG SIEVTDFTQG ADQIDLSNIT GVEDFDDLAA
FLLSGGGTST LTFDITEVDQ LQLIIQAEED LEASDFIF
//
