ID B6BDY0_9RHOB Unreviewed; 256 AA.
AC B6BDY0;
DT 25-NOV-2008, integrated into UniProtKB/TrEMBL.
DT 25-NOV-2008, sequence version 1.
DT 24-JAN-2024, entry version 69.
DE RecName: Full=Pyruvate dehydrogenase complex repressor {ECO:0000256|ARBA:ARBA00039592};
GN Name=pdhR {ECO:0000313|EMBL:EDZ47347.1};
GN ORFNames=RBY4I_2565 {ECO:0000313|EMBL:EDZ47347.1};
OS Rhodobacterales bacterium Y4I.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales.
OX NCBI_TaxID=439496 {ECO:0000313|EMBL:EDZ47347.1, ECO:0000313|Proteomes:UP000005133};
RN [1] {ECO:0000313|EMBL:EDZ47347.1, ECO:0000313|Proteomes:UP000005133}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Y4I {ECO:0000313|EMBL:EDZ47347.1,
RC ECO:0000313|Proteomes:UP000005133};
RA Moran M.A., Buchan A., Ferriera S., Johnson J., Kravitz S., Beeson K.,
RA Sutton G., Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Transcriptional repressor for the pyruvate dehydrogenase
CC complex genes aceEF and lpd. {ECO:0000256|ARBA:ARBA00037357}.
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DR EMBL; DS995281; EDZ47347.1; -; Genomic_DNA.
DR AlphaFoldDB; B6BDY0; -.
DR STRING; 439496.RBY4I_2565; -.
DR eggNOG; COG2186; Bacteria.
DR HOGENOM; CLU_017584_9_5_5; -.
DR OrthoDB; 5450856at2; -.
DR Proteomes; UP000005133; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd07377; WHTH_GntR; 1.
DR Gene3D; 1.20.120.530; GntR ligand-binding domain-like; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011711; GntR_C.
DR InterPro; IPR008920; TF_FadR/GntR_C.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR43537:SF34; PYRUVATE DEHYDROGENASE COMPLEX REPRESSOR; 1.
DR PANTHER; PTHR43537; TRANSCRIPTIONAL REGULATOR, GNTR FAMILY; 1.
DR Pfam; PF07729; FCD; 1.
DR Pfam; PF00392; GntR; 1.
DR PRINTS; PR00035; HTHGNTR.
DR SMART; SM00895; FCD; 1.
DR SMART; SM00345; HTH_GNTR; 1.
DR SUPFAM; SSF48008; GntR ligand-binding domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Pyruvate {ECO:0000313|EMBL:EDZ47347.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000005133};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 9..77
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
FT COILED 228..255
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 256 AA; 28496 MW; AF3164A3D73AAC5F CRC64;
MPFQKVQPEK LSASVVKQIE QLILRGILSP GERLPAEREL AERLGVSRPS LRDAIGELQA
RGLLASKAGS GVFVADVLGS AFSPALIQLF ATHDEAVFDY LSFRRDMEGL AAERAARFGS
DYDLQVIQAI FDKMEAAGNP AVSEEAAQLD AQFHSAIMDA SHNVIMLHMM RSMFDLLREG
VFYNRRIMFQ QHTTYEALLE QHRAINAALQ ARDPQAARTA VEAHLDYVKQ ALTDHQRAER
NAEVAKQRLE HETGKG
//
