ID B6CN60_9NEOP Unreviewed; 344 AA.
AC B6CN60;
DT 25-NOV-2008, integrated into UniProtKB/TrEMBL.
DT 25-NOV-2008, sequence version 1.
DT 24-JAN-2024, entry version 45.
DE SubName: Full=Elongation factor 1-alpha {ECO:0000313|EMBL:ACD75930.1};
DE Flags: Fragment;
GN Name=EF1a {ECO:0000313|EMBL:ACD75930.1};
OS Aetheca wagneri.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Siphonaptera; Ceratophyllidae; Aetheca.
OX NCBI_TaxID=173773 {ECO:0000313|EMBL:ACD75930.1};
RN [1] {ECO:0000313|EMBL:ACD75930.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=F032 {ECO:0000313|EMBL:ACD75930.1};
RA Whiting M.F., Whiting A.S., Hastriter M.W., Dittmar K.;
RT "A molecular phylogeny of fleas (Insecta: Siphonaptera): origins and host
RT associations.";
RL Cladistics 24:677-707(2008).
CC -!- FUNCTION: This protein promotes the GTP-dependent binding of aminoacyl-
CC tRNA to the A-site of ribosomes during protein biosynthesis.
CC {ECO:0000256|ARBA:ARBA00003982}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A
CC subfamily. {ECO:0000256|ARBA:ARBA00007249}.
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DR EMBL; EU336254; ACD75930.1; -; Genomic_DNA.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR CDD; cd03693; EF1_alpha_II; 1.
DR CDD; cd03705; EF1_alpha_III; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 2.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR InterPro; IPR004539; Transl_elong_EF1A_euk/arc.
DR InterPro; IPR004160; Transl_elong_EFTu/EF1A_C.
DR NCBIfam; TIGR00483; EF-1_alpha; 1.
DR PANTHER; PTHR23115:SF236; ELONGATION FACTOR 1-ALPHA 1; 1.
DR PANTHER; PTHR23115; TRANSLATION FACTOR; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF03143; GTP_EFTU_D3; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 3: Inferred from homology;
KW Elongation factor {ECO:0000313|EMBL:ACD75930.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Protein biosynthesis {ECO:0000313|EMBL:ACD75930.1}.
FT DOMAIN 1..159
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ACD75930.1"
FT NON_TER 344
FT /evidence="ECO:0000313|EMBL:ACD75930.1"
SQ SEQUENCE 344 AA; 37246 MW; 14569DCAE880E46B CRC64;
KYYVTIIDAP GHRDFIKNMI TGTSQADCAV LIVAAGXGEF EAGISKNGQT REHALLAFTL
GVKQLIVGVN KMDSTEPPYS EXRFEEIKKE VSSYIKKIGY NPAAVAFVPI SGWHGDNMLE
VSTKMSWFKG WNVERKEGKA DGKCLIEALD AILPPARPTD KALRLPLQDV YKIGGIGTVP
VGRVETGVLK PGTVVVFAPA NITTEVKSVE MHHEALQEAV PGDNVGFNVK NVSVKELRRG
YVAGDSKASP PRGAADFTAQ VIVLNHPGQI SNGYTPVLDC HTAHIACKFA EIKEKVDRRT
GKSTEDNPKA IKSGDAAIVN LVPSKPMCVE SFQEFPPLGR FAVR
//
