ID B6CNA0_9NEOP Unreviewed; 351 AA.
AC B6CNA0;
DT 25-NOV-2008, integrated into UniProtKB/TrEMBL.
DT 25-NOV-2008, sequence version 1.
DT 24-JAN-2024, entry version 43.
DE SubName: Full=Elongation factor 1-alpha {ECO:0000313|EMBL:ACD75970.1};
DE Flags: Fragment;
GN Name=EF1a {ECO:0000313|EMBL:ACD75970.1};
OS Dolichopsyllus stylosus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Siphonaptera; Leptopsyllidae; Dolichopsyllus.
OX NCBI_TaxID=507045 {ECO:0000313|EMBL:ACD75970.1};
RN [1] {ECO:0000313|EMBL:ACD75970.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=F113 {ECO:0000313|EMBL:ACD75970.1};
RA Whiting M.F., Whiting A.S., Hastriter M.W., Dittmar K.;
RT "A molecular phylogeny of fleas (Insecta: Siphonaptera): origins and host
RT associations.";
RL Cladistics 24:677-707(2008).
CC -!- FUNCTION: This protein promotes the GTP-dependent binding of aminoacyl-
CC tRNA to the A-site of ribosomes during protein biosynthesis.
CC {ECO:0000256|ARBA:ARBA00003982}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A
CC subfamily. {ECO:0000256|ARBA:ARBA00007249}.
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DR EMBL; EU336295; ACD75970.1; -; Genomic_DNA.
DR AlphaFoldDB; B6CNA0; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR CDD; cd03693; EF1_alpha_II; 1.
DR CDD; cd03705; EF1_alpha_III; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 2.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR InterPro; IPR004539; Transl_elong_EF1A_euk/arc.
DR InterPro; IPR004160; Transl_elong_EFTu/EF1A_C.
DR NCBIfam; TIGR00483; EF-1_alpha; 1.
DR PANTHER; PTHR23115:SF236; ELONGATION FACTOR 1-ALPHA 1; 1.
DR PANTHER; PTHR23115; TRANSLATION FACTOR; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF03143; GTP_EFTU_D3; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 3: Inferred from homology;
KW Elongation factor {ECO:0000313|EMBL:ACD75970.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Protein biosynthesis {ECO:0000313|EMBL:ACD75970.1}.
FT DOMAIN 1..166
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ACD75970.1"
FT NON_TER 351
FT /evidence="ECO:0000313|EMBL:ACD75970.1"
SQ SEQUENCE 351 AA; 38123 MW; B9E8A55CD889B8ED CRC64;
LWKFETAKYY VTIIDAPGHR DFIKNMITGT SQADCAVLIV AAGVGEFEAG ISKNGQTREH
ALLAFTLGVK QLIVGVNKMD STEPPYSENR FEEIKKEVSS YIKKIGYNPA AVAFVPISGW
HGDNMLEVSS KMGWFKGWNI ERKEGKADGK CLIEALDAIL PPARPTDKPL RLPLQDVYKI
GGIGTVPVGR VETGVLKPGT VVVFAPANLT TEVKSVEMHH EALQEAVPGD NVGFNVKNVS
VKELRRGYVA GDSKASPPRG AADFTAQVIV LNHPGQISNG YTPVLDCHTA HIACKFAEIK
EKVDRRTGKS TEENPKAIKS GDAAIVNLVP SKPMCVESFQ EFPPLGRFAV R
//
