ID B6D562_9ACTO Unreviewed; 359 AA.
AC B6D562;
DT 25-NOV-2008, integrated into UniProtKB/TrEMBL.
DT 25-NOV-2008, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE RecName: Full=exo-alpha-sialidase {ECO:0000256|ARBA:ARBA00012733};
DE EC=3.2.1.18 {ECO:0000256|ARBA:ARBA00012733};
DE Flags: Fragment;
GN Name=nanH {ECO:0000313|EMBL:ACH92891.1};
OS Actinomyces oris.
OC Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC Actinomyces.
OX NCBI_TaxID=544580 {ECO:0000313|EMBL:ACH92891.1};
RN [1] {ECO:0000313|EMBL:ACH92891.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=S56D {ECO:0000313|EMBL:ACH92891.1};
RA Do T., Henssge U., Gilbert S.C., Clark D., Beighton D.;
RT "Evidence for recombination between a sialidase (nanH) of Actinomyces
RT naeslundii and Actinomyces oris, previously named 'Actinomyces naeslundii
RT genospecies 1 and 2'.";
RL FEMS Microbiol. Lett. 288:156-162(2008).
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DR EMBL; EU805669; ACH92891.1; -; Genomic_DNA.
DR AlphaFoldDB; B6D562; -.
DR CAZy; GH33; Glycoside Hydrolase Family 33.
DR GO; GO:0004308; F:exo-alpha-sialidase activity; IEA:InterPro.
DR CDD; cd15482; Sialidase_non-viral; 1.
DR Gene3D; 2.120.10.10; -; 1.
DR InterPro; IPR011040; Sialidase.
DR InterPro; IPR026856; Sialidase_fam.
DR InterPro; IPR036278; Sialidase_sf.
DR PANTHER; PTHR10628; SIALIDASE; 1.
DR PANTHER; PTHR10628:SF25; SIALIDASE-1; 1.
DR Pfam; PF13088; BNR_2; 1.
DR SUPFAM; SSF50939; Sialidases; 1.
PE 4: Predicted;
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 75..358
FT /note="Sialidase"
FT /evidence="ECO:0000259|Pfam:PF13088"
FT REGION 1..38
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 51..92
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10..38
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 66..92
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ACH92891.1"
FT NON_TER 359
FT /evidence="ECO:0000313|EMBL:ACH92891.1"
SQ SEQUENCE 359 AA; 38334 MW; 8225BFE0F3AABCFA CRC64;
VGDHPQATPT PAPDASTELP ASMSQAQHLA PNTATDNYRI PAITTAPNGD LLISYDERPK
DNGNGGSDAP NPNHIVQRRS TDGGKTWSAP TYIHQGTETG KKVGYSDPSY VVDHQTGTIF
NFHVKSYDQG WGGSQAGTDP DNRGIIQAEV STSTDNGWTW THRTITADIT KDNPWTARFA
ASGQGIQIQH GPHAGRLVQQ YTIRTAGGAV QAVSVYSDDH GKTWQAGTPI GTGMDENKVV
ELSDGSLMLN SRASDGSGFR KVAHSTDGGQ TWSEPVSDQN LPDSVDNAQI IRAFPNAAAD
DPRAKVLLLS HSPNPKPWSR DRGTISMSCD DGASWTTSKV FHEPFVGYTT IAVQSDGSI
//
