ID B6D589_9ACTO Unreviewed; 359 AA.
AC B6D589;
DT 25-NOV-2008, integrated into UniProtKB/TrEMBL.
DT 25-NOV-2008, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE RecName: Full=exo-alpha-sialidase {ECO:0000256|ARBA:ARBA00012733};
DE EC=3.2.1.18 {ECO:0000256|ARBA:ARBA00012733};
DE Flags: Fragment;
GN Name=nanH {ECO:0000313|EMBL:ACH92918.1};
OS Actinomyces oris.
OC Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC Actinomyces.
OX NCBI_TaxID=544580 {ECO:0000313|EMBL:ACH92918.1};
RN [1] {ECO:0000313|EMBL:ACH92918.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=P5K {ECO:0000313|EMBL:ACH92918.1};
RA Do T., Henssge U., Gilbert S.C., Clark D., Beighton D.;
RT "Evidence for recombination between a sialidase (nanH) of Actinomyces
RT naeslundii and Actinomyces oris, previously named 'Actinomyces naeslundii
RT genospecies 1 and 2'.";
RL FEMS Microbiol. Lett. 288:156-162(2008).
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DR EMBL; EU805696; ACH92918.1; -; Genomic_DNA.
DR AlphaFoldDB; B6D589; -.
DR CAZy; GH33; Glycoside Hydrolase Family 33.
DR GO; GO:0004308; F:exo-alpha-sialidase activity; IEA:InterPro.
DR CDD; cd15482; Sialidase_non-viral; 1.
DR Gene3D; 2.120.10.10; -; 1.
DR InterPro; IPR011040; Sialidase.
DR InterPro; IPR026856; Sialidase_fam.
DR InterPro; IPR036278; Sialidase_sf.
DR PANTHER; PTHR10628; SIALIDASE; 1.
DR PANTHER; PTHR10628:SF25; SIALIDASE-1; 1.
DR Pfam; PF13088; BNR_2; 1.
DR SUPFAM; SSF50939; Sialidases; 1.
PE 4: Predicted;
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 75..358
FT /note="Sialidase"
FT /evidence="ECO:0000259|Pfam:PF13088"
FT REGION 1..92
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 255..280
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 18..42
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 66..92
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 264..280
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ACH92918.1"
FT NON_TER 359
FT /evidence="ECO:0000313|EMBL:ACH92918.1"
SQ SEQUENCE 359 AA; 38411 MW; 7F979968FC31CD4F CRC64;
VGDHPQATPA PAPDASTELP ASMSQAQHVA PNTATDNYRI PAITTAPNGD LLISYDERPK
DNGNGGSDAP NPNHIVQRRS TDGGKTWSAP TYIHQGTETG KRVGYSDPSY VVDHQTGTIF
NFHVKSYDQG WGGSQAGTDP DNRGIIQAEV STSTDNGWTW THRTITADIT KDNPWTARFA
ASGQGIQIQH GPHAGRLVQQ YTIRTAGGAV QAVSVYSDDH GKTWQAGTPI GTGMDENKVV
ELSDGSLMLN SRASDGSGFR KVAHSTDGGQ TWSEPVSDQN LPDSVDKPEI IRAFPNAAPD
DPRAKVLLLS HSPNPKPWSR DRGTISMSCD DGPSWTTSKV FHEPFVGYTT IAVQSDGSI
//
