ID   B6E108_ACICA            Unreviewed;       274 AA.
AC   B6E108;
DT   25-NOV-2008, integrated into UniProtKB/TrEMBL.
DT   25-NOV-2008, sequence version 1.
DT   24-JAN-2024, entry version 31.
DE   SubName: Full=OXA-146 carbapenemase {ECO:0000313|EMBL:ACI22666.1};
GN   Name=blaOXA-146 {ECO:0000313|EMBL:ACI22666.1};
OS   Acinetobacter calcoaceticus.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC   Acinetobacter; Acinetobacter calcoaceticus/baumannii complex.
OX   NCBI_TaxID=471 {ECO:0000313|EMBL:ACI22666.1};
RN   [1] {ECO:0000313|EMBL:ACI22666.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=AC518 {ECO:0000313|EMBL:ACI22666.1};
RA   Li J., Zhang X.;
RT   "Sequence analysis of OXA-23, a novel class D beta-lactamase with
RT   carbapenemase activity in an Acinetobacter calcoaceticus clinical strain.";
RL   Submitted (SEP-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the class-D beta-lactamase family.
CC       {ECO:0000256|ARBA:ARBA00007898}.
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DR   EMBL; FJ194460; ACI22666.1; -; Genomic_DNA.
DR   AlphaFoldDB; B6E108; -.
DR   SMR; B6E108; -.
DR   GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR   Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR001460; PCN-bd_Tpept.
DR   PANTHER; PTHR30627:SF6; BETA-LACTAMASE YBXI-RELATED; 1.
DR   PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR   Pfam; PF00905; Transpeptidase; 1.
DR   SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
FT   DOMAIN          48..264
FT                   /note="Penicillin-binding protein transpeptidase"
FT                   /evidence="ECO:0000259|Pfam:PF00905"
SQ   SEQUENCE   274 AA;  31050 MW;  D07CAA58CB66C392 CRC64;
     MNKYFTCYVV ASLFLSGCTV QHNLINETPS QIVQGHNQVI HQYFDEKNTS GVLVIQTDKK
     INLYGNALSR ANTEYVPAST FKMLNALIGL ENQKTDINEI FKWKGEKRSF TAWEKDMTLG
     EAMKLSAVPV YQELARRIGL DLMQKEVKRI GFGNAEIGQQ VDNFWLVGPL KVTPIQEVEF
     VSQLAHTQLP FSEKVQANVK NMLLLEESNG YKIFGKTGWA AMDIKPQVGW LTGWVEQPDG
     KIVAFALNME MRSEMPASIR NELLMKSLKQ LNII
//