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Database: UniProt
Entry: B6ENU2
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ID   UBIA_ALISL              Reviewed;         285 AA.
AC   B6ENU2;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   25-NOV-2008, sequence version 1.
DT   01-OCT-2014, entry version 41.
DE   RecName: Full=4-hydroxybenzoate octaprenyltransferase {ECO:0000255|HAMAP-Rule:MF_01635};
DE            EC=2.5.1.- {ECO:0000255|HAMAP-Rule:MF_01635};
DE   AltName: Full=4-HB polyprenyltransferase {ECO:0000255|HAMAP-Rule:MF_01635};
GN   Name=ubiA {ECO:0000255|HAMAP-Rule:MF_01635};
GN   OrderedLocusNames=VSAL_I2895;
OS   Aliivibrio salmonicida (strain LFI1238) (Vibrio salmonicida (strain
OS   LFI1238)).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales;
OC   Vibrionaceae; Aliivibrio.
OX   NCBI_TaxID=316275;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LFI1238;
RX   PubMed=19099551; DOI=10.1186/1471-2164-9-616;
RA   Hjerde E., Lorentzen M.S., Holden M.T., Seeger K., Paulsen S.,
RA   Bason N., Churcher C., Harris D., Norbertczak H., Quail M.A.,
RA   Sanders S., Thurston S., Parkhill J., Willassen N.P., Thomson N.R.;
RT   "The genome sequence of the fish pathogen Aliivibrio salmonicida
RT   strain LFI1238 shows extensive evidence of gene decay.";
RL   BMC Genomics 9:616-616(2008).
CC   -!- FUNCTION: Synthesis of 3-octaprenyl-4-hydroxybenzoate.
CC       {ECO:0000255|HAMAP-Rule:MF_01635}.
CC   -!- CATALYTIC ACTIVITY: 4-hydroxybenzoate + farnesylfarnesylgeraniol =
CC       3-octaprenyl-4-hydroxybenzoate. {ECO:0000255|HAMAP-Rule:MF_01635}.
CC   -!- COFACTOR: Magnesium. {ECO:0000255|HAMAP-Rule:MF_01635}.
CC   -!- PATHWAY: Cofactor biosynthesis; ubiquinone biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_01635}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01635}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01635}.
CC   -!- SIMILARITY: Belongs to the UbiA prenyltransferase family.
CC       {ECO:0000255|HAMAP-Rule:MF_01635}.
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DR   EMBL; FM178379; CAQ80579.1; -; Genomic_DNA.
DR   RefSeq; YP_002264225.1; NC_011312.1.
DR   STRING; 316275.VSAL_I2895; -.
DR   EnsemblBacteria; CAQ80579; CAQ80579; VSAL_I2895.
DR   GeneID; 6988987; -.
DR   KEGG; vsa:VSAL_I2895; -.
DR   PATRIC; 20856326; VBIAliSal95923_3134.
DR   eggNOG; COG0382; -.
DR   HOGENOM; HOG000003696; -.
DR   KO; K03179; -.
DR   OMA; GMPMAFT; -.
DR   OrthoDB; EOG680X3B; -.
DR   UniPathway; UPA00232; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004659; F:prenyltransferase activity; IEA:InterPro.
DR   GO; GO:0006744; P:ubiquinone biosynthetic process; IEA:UniProtKB-UniPathway.
DR   HAMAP; MF_01635; UbiA; 1.
DR   InterPro; IPR006370; HB_polyprenyl-transferase.
DR   InterPro; IPR000537; UbiA_prenyltransferase.
DR   Pfam; PF01040; UbiA; 1.
DR   TIGRFAMs; TIGR01474; ubiA_proteo; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Complete proteome; Magnesium;
KW   Membrane; Transferase; Transmembrane; Transmembrane helix;
KW   Ubiquinone biosynthesis.
FT   CHAIN         1    285       4-hydroxybenzoate octaprenyltransferase.
FT                                /FTId=PRO_1000186654.
FT   TRANSMEM     20     39       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01635}.
FT   TRANSMEM     44     66       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01635}.
FT   TRANSMEM     93    113       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01635}.
FT   TRANSMEM    134    154       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01635}.
FT   TRANSMEM    166    186       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01635}.
FT   TRANSMEM    209    229       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01635}.
FT   TRANSMEM    233    253       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01635}.
FT   TRANSMEM    265    285       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01635}.
SQ   SEQUENCE   285 AA;  31679 MW;  D6FA47CC5EB7561A CRC64;
     MTLSKAKAFW QLTRMNRPIG SLLLLWPTLW ALFLAADGIP DWHVLIVFIL GVVFMRSAGC
     VINDFADRKV DGHVKRTANR PLPSGLVSSK EALILFSVLV TCSFILVLTM NTLTIMLSSI
     GVLLAIAYPF MKRITYLPQF VLGLAFSWAI PMAYAAESNQ VPPEAWLLFV INAVWTIAYD
     TQYAMVDRDD DLNIGIKSTA ILFGRFDKLM IGLLQLTVLT LLIALGIQLS LPSLYNWGVL
     AAAGCFVYQQ WLIKGREREA CFEAFLNNNY VGGFIFVAIS ASVLI
//
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