ID UBIA_ALISL Reviewed; 285 AA.
AC B6ENU2;
DT 28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 25-NOV-2008, sequence version 1.
DT 01-MAY-2013, entry version 35.
DE RecName: Full=4-hydroxybenzoate octaprenyltransferase;
DE EC=2.5.1.-;
DE AltName: Full=4-HB polyprenyltransferase;
GN Name=ubiA; OrderedLocusNames=VSAL_I2895;
OS Aliivibrio salmonicida (strain LFI1238) (Vibrio salmonicida (strain
OS LFI1238)).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales;
OC Vibrionaceae; Aliivibrio.
OX NCBI_TaxID=316275;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LFI1238;
RA Hjerde E., Lorentzen M.S., Holden M.T.G., Seeger K., Paulsen S.,
RA Bason N., Churcher C., Harris D., Norbertczak H., Quail M.A.,
RA Sanders S., Thurston S., Parkhill J., Willassen N.-P., Thomson N.R.;
RT "The complete genome sequence of the fish pathogen Aliivibrio
RT salmonicida strain LFI1238.";
RL Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Synthesis of 3-octaprenyl-4-hydroxybenzoate (By
CC similarity).
CC -!- CATALYTIC ACTIVITY: 4-hydroxybenzoate + farnesylfarnesylgeraniol =
CC 3-octaprenyl-4-hydroxybenzoate.
CC -!- COFACTOR: Magnesium (By similarity).
CC -!- PATHWAY: Cofactor biosynthesis; ubiquinone biosynthesis.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane
CC protein (By similarity).
CC -!- SIMILARITY: Belongs to the UbiA prenyltransferase family.
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DR EMBL; FM178379; CAQ80579.1; -; Genomic_DNA.
DR RefSeq; YP_002264225.1; NC_011312.1.
DR STRING; 316275.VSAL_I2895; -.
DR EnsemblBacteria; CAQ80579; CAQ80579; VSAL_I2895.
DR GeneID; 6988987; -.
DR KEGG; vsa:VSAL_I2895; -.
DR PATRIC; 20856326; VBIAliSal95923_3134.
DR eggNOG; COG0382; -.
DR HOGENOM; HOG000003696; -.
DR KO; K03179; -.
DR OMA; YHYTLIR; -.
DR ProtClustDB; PRK12848; -.
DR UniPathway; UPA00232; -.
DR GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008412; F:4-hydroxybenzoate octaprenyltransferase activity; IEA:HAMAP.
DR GO; GO:0006744; P:ubiquinone biosynthetic process; IEA:HAMAP.
DR HAMAP; MF_01635; UbiA; 1; -.
DR InterPro; IPR006370; HB_polyprenyl-transferase.
DR InterPro; IPR000537; UbiA_prenyltransferase.
DR Pfam; PF01040; UbiA; 1.
DR TIGRFAMs; TIGR01474; ubiA_proteo; 1.
DR PROSITE; PS00943; UBIA; FALSE_NEG.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Complete proteome; Magnesium;
KW Membrane; Transferase; Transmembrane; Transmembrane helix;
KW Ubiquinone biosynthesis.
FT CHAIN 1 285 4-hydroxybenzoate octaprenyltransferase.
FT /FTId=PRO_1000186654.
FT TRANSMEM 20 39 Helical; (Potential).
FT TRANSMEM 44 66 Helical; (Potential).
FT TRANSMEM 93 113 Helical; (Potential).
FT TRANSMEM 134 154 Helical; (Potential).
FT TRANSMEM 166 186 Helical; (Potential).
FT TRANSMEM 209 229 Helical; (Potential).
FT TRANSMEM 233 253 Helical; (Potential).
FT TRANSMEM 265 285 Helical; (Potential).
SQ SEQUENCE 285 AA; 31679 MW; D6FA47CC5EB7561A CRC64;
MTLSKAKAFW QLTRMNRPIG SLLLLWPTLW ALFLAADGIP DWHVLIVFIL GVVFMRSAGC
VINDFADRKV DGHVKRTANR PLPSGLVSSK EALILFSVLV TCSFILVLTM NTLTIMLSSI
GVLLAIAYPF MKRITYLPQF VLGLAFSWAI PMAYAAESNQ VPPEAWLLFV INAVWTIAYD
TQYAMVDRDD DLNIGIKSTA ILFGRFDKLM IGLLQLTVLT LLIALGIQLS LPSLYNWGVL
AAAGCFVYQQ WLIKGREREA CFEAFLNNNY VGGFIFVAIS ASVLI
//
