ID B6EUK9_9MICO Unreviewed; 308 AA.
AC B6EUK9;
DT 16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Extradiol dioxygenase {ECO:0000313|EMBL:BAG80723.1};
GN Name=dfdB {ECO:0000313|EMBL:BAG80723.1};
OS Terrabacter sp. YK3.
OG Plasmid pYK3 {ECO:0000313|EMBL:BAG80723.1}.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Intrasporangiaceae;
OC Terrabacter.
OX NCBI_TaxID=169538 {ECO:0000313|EMBL:BAG80723.1};
RN [1] {ECO:0000313|EMBL:BAG80723.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=YK3 {ECO:0000313|EMBL:BAG80723.1};
RC PLASMID=pYK3 {ECO:0000313|EMBL:BAG80723.1};
RX PubMed=12147464; DOI=10.1128/AEM.68.8.3716-3723.2002;
RA Iida T., Mukouzaka Y., Nakamura K., Kudo T.;
RT "Plasmid-borne genes code for an angular dioxygenase involved in
RT dibenzofuran degradation by Terrabacter sp. strain YK3.";
RL Appl. Environ. Microbiol. 68:3716-3723(2002).
RN [2] {ECO:0000313|EMBL:BAG80723.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=YK3 {ECO:0000313|EMBL:BAG80723.1};
RC PLASMID=pYK3 {ECO:0000313|EMBL:BAG80723.1};
RX PubMed=18952799; DOI=10.1128/JB.01112-08;
RA Iida T., Waki T., Nakamura K., Mukouzaka Y., Kudo T.;
RT "The GAF-like-domain-containing transcriptional regulator DfdR is a sensor
RT protein for dibenzofuran and several hydrophobic aromatic compounds.";
RL J. Bacteriol. 191:123-134(2009).
CC -!- COFACTOR:
CC Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
CC Evidence={ECO:0000256|ARBA:ARBA00001954,
CC ECO:0000256|RuleBase:RU000683};
CC -!- SIMILARITY: Belongs to the extradiol ring-cleavage dioxygenase family.
CC {ECO:0000256|ARBA:ARBA00008784, ECO:0000256|RuleBase:RU000683}.
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DR EMBL; AB075242; BAG80723.1; -; Genomic_DNA.
DR AlphaFoldDB; B6EUK9; -.
DR GO; GO:0051213; F:dioxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0008198; F:ferrous iron binding; IEA:InterPro.
DR GO; GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
DR CDD; cd07237; BphC1-RGP6_C_like; 1.
DR CDD; cd07252; BphC1-RGP6_N_like; 1.
DR Gene3D; 3.10.180.10; 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1; 2.
DR InterPro; IPR029068; Glyas_Bleomycin-R_OHBP_Dase.
DR InterPro; IPR004360; Glyas_Fos-R_dOase_dom.
DR InterPro; IPR037523; VOC.
DR InterPro; IPR000486; Xdiol_ring_cleave_dOase_1/2.
DR PANTHER; PTHR21366; GLYOXALASE FAMILY PROTEIN; 1.
DR PANTHER; PTHR21366:SF34; IRON-DEPENDENT EXTRADIOL DIOXYGENASE; 1.
DR Pfam; PF00903; Glyoxalase; 1.
DR SUPFAM; SSF54593; Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase; 2.
DR PROSITE; PS00082; EXTRADIOL_DIOXYGENAS; 1.
DR PROSITE; PS51819; VOC; 2.
PE 3: Inferred from homology;
KW Aromatic hydrocarbons catabolism {ECO:0000256|ARBA:ARBA00022797,
KW ECO:0000256|RuleBase:RU000683};
KW Dioxygenase {ECO:0000256|ARBA:ARBA00022964, ECO:0000256|RuleBase:RU000683};
KW Iron {ECO:0000256|RuleBase:RU000683};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU000683}; Plasmid {ECO:0000313|EMBL:BAG80723.1}.
FT DOMAIN 6..120
FT /note="VOC"
FT /evidence="ECO:0000259|PROSITE:PS51819"
FT DOMAIN 143..267
FT /note="VOC"
FT /evidence="ECO:0000259|PROSITE:PS51819"
SQ SEQUENCE 308 AA; 33982 MW; DD6E4D018EB0CB1D CRC64;
MGKVKELAYV GYEVSDLAAW EHFGVDLLGM QFGEKTTSGF TLRTDHKAHR WVVEAGAADD
LVVSGYEVAS EPELDAIVQG LGSAGFEVTE GDAALAADRK VDRIFVTTDP MGNRVELVSG
FADAETPFES TKLLGSFVTG NGGAGHQVLL TGDVSREEYL AFYVDLLGFK ISDIIVEEVA
PGIVADLIFL HCNPRHHTVA FGKLPFPKVT HHFMLEVSDI RDVGLAYDRC LDARQPFEMT
LGMHPNDRMF SFYVRTPSGF NVEYGWGALL IDDETWEVKT LDRLHSWGHR PPQVLAEQLA
HTATDEVH
//
