ID B6EV64_MACFA Unreviewed; 175 AA.
AC B6EV64;
DT 16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=MHC class II antigen DR alpha chain {ECO:0000313|EMBL:BAG82024.1};
DE Flags: Fragment;
GN Name=Mafa-DRA {ECO:0000313|EMBL:BAG82024.1};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541 {ECO:0000313|EMBL:BAG82024.1};
RN [1] {ECO:0000313|EMBL:BAG82024.1}
RP NUCLEOTIDE SEQUENCE.
RA Shimizu S., Shiina T., Kohara S., Yanagiya K., Hosomichi K., Sano K.,
RA Ogasawara K., Torii R., Kulski J.K., Inoko H.;
RT "Novel cynomolgus macaque MHC-DRA polymorphisms in three South-East Asian
RT population.";
RL Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the MHC class II family.
CC {ECO:0000256|RuleBase:RU004238}.
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DR EMBL; AB306652; BAG82024.1; -; Genomic_DNA.
DR AlphaFoldDB; B6EV64; -.
DR GO; GO:0042613; C:MHC class II protein complex; IEA:UniProtKB-KW.
DR GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW.
DR GO; GO:0002504; P:antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003006; Ig/MHC_CS.
DR InterPro; IPR003597; Ig_C1-set.
DR InterPro; IPR011162; MHC_I/II-like_Ag-recog.
DR InterPro; IPR014745; MHC_II_a/b_N.
DR InterPro; IPR001003; MHC_II_a_N.
DR PANTHER; PTHR19944:SF86; HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN; 1.
DR PANTHER; PTHR19944; MHC CLASS II-RELATED; 1.
DR Pfam; PF07654; C1-set; 1.
DR Pfam; PF00993; MHC_II_alpha; 1.
DR SMART; SM00407; IGc1; 1.
DR SMART; SM00920; MHC_II_alpha; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR SUPFAM; SSF54452; MHC antigen-recognition domain; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
DR PROSITE; PS00290; IG_MHC; 1.
PE 3: Inferred from homology;
KW Adaptive immunity {ECO:0000256|ARBA:ARBA00023130};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Immunity {ECO:0000256|ARBA:ARBA00022859};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW MHC II {ECO:0000256|ARBA:ARBA00023182};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 84..164
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:BAG82024.1"
FT NON_TER 175
FT /evidence="ECO:0000313|EMBL:BAG82024.1"
SQ SEQUENCE 175 AA; 20052 MW; 7B900C9A97359EAD CRC64;
EHVIIQAEFY LNPDQSGEFM FDFDGDEIFH VDMAKKETVW RLEEFGRFAS FEAQGALANI
AVDKANLEIM TKRSNNTPIT NVPPEVTVLT NSPVELGEPN VLICFIDKFS PPVVKVTWLK
NGKPVTTGVS ETVFLPREDH LFRKFHYLPF LPSTEDIYDC KVEHWGLDAP LLKHW
//
