ID B6H6E5_PENRW Unreviewed; 917 AA.
AC B6H6E5;
DT 16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE RecName: Full=alpha-L-rhamnosidase {ECO:0000256|ARBA:ARBA00012652};
DE EC=3.2.1.40 {ECO:0000256|ARBA:ARBA00012652};
GN ORFNames=Pc15g02110 {ECO:0000313|EMBL:CAP83097.1}, PCH_Pc15g02110
GN {ECO:0000313|EMBL:CAP83097.1};
OS Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin
OS 54-1255) (Penicillium chrysogenum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium;
OC Penicillium chrysogenum species complex.
OX NCBI_TaxID=500485 {ECO:0000313|EMBL:CAP83097.1, ECO:0000313|Proteomes:UP000000724};
RN [1] {ECO:0000313|EMBL:CAP83097.1, ECO:0000313|Proteomes:UP000000724}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255
RC {ECO:0000313|Proteomes:UP000000724};
RX PubMed=18820685; DOI=10.1038/nbt.1498;
RA van den Berg M.A., Albang R., Albermann K., Badger J.H., Daran J.-M.,
RA Driessen A.J.M., Garcia-Estrada C., Fedorova N.D., Harris D.M.,
RA Heijne W.H.M., Joardar V.S., Kiel J.A.K.W., Kovalchuk A., Martin J.F.,
RA Nierman W.C., Nijland J.G., Pronk J.T., Roubos J.A., van der Klei I.J.,
RA van Peij N.N.M.E., Veenhuis M., von Doehren H., Wagner C., Wortman J.R.,
RA Bovenberg R.A.L.;
RT "Genome sequencing and analysis of the filamentous fungus Penicillium
RT chrysogenum.";
RL Nat. Biotechnol. 26:1161-1168(2008).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing alpha-L-rhamnose residues
CC in alpha-L-rhamnosides.; EC=3.2.1.40;
CC Evidence={ECO:0000256|ARBA:ARBA00001445};
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DR EMBL; AM920430; CAP83097.1; -; Genomic_DNA.
DR RefSeq; XP_002560425.1; XM_002560379.1.
DR AlphaFoldDB; B6H6E5; -.
DR STRING; 500485.B6H6E5; -.
DR CAZy; GH78; Glycoside Hydrolase Family 78.
DR GeneID; 8317569; -.
DR KEGG; pcs:Pc15g02110; -.
DR VEuPathDB; FungiDB:PCH_Pc15g02110; -.
DR eggNOG; ENOG502QW2K; Eukaryota.
DR HOGENOM; CLU_002926_1_1_1; -.
DR OMA; TYMPHTS; -.
DR OrthoDB; 5488371at2759; -.
DR BioCyc; PCHR:PC15G02110-MONOMER; -.
DR Proteomes; UP000000724; Contig Pc00c15.
DR GO; GO:0030596; F:alpha-L-rhamnosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 1.50.10.10; -; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.60.420.10; Maltose phosphorylase, domain 3; 1.
DR InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR InterPro; IPR035396; Bac_rhamnosid6H.
DR InterPro; IPR035398; Bac_rhamnosid_C.
DR InterPro; IPR013737; Bac_rhamnosid_N.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR008902; Rhamnosid_concanavalin.
DR PANTHER; PTHR33307; ALPHA-RHAMNOSIDASE (EUROFUNG); 1.
DR PANTHER; PTHR33307:SF5; CELLULOSE-BINDING SDE182 NUCLEOSIDE HYDROLASE-LIKE DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR Pfam; PF05592; Bac_rhamnosid; 1.
DR Pfam; PF17389; Bac_rhamnosid6H; 1.
DR Pfam; PF17390; Bac_rhamnosid_C; 1.
DR Pfam; PF08531; Bac_rhamnosid_N; 1.
DR SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000000724}.
FT DOMAIN 173..351
FT /note="Bacterial alpha-L-rhamnosidase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08531"
FT DOMAIN 363..452
FT /note="Alpha-L-rhamnosidase concanavalin-like"
FT /evidence="ECO:0000259|Pfam:PF05592"
FT DOMAIN 476..815
FT /note="Alpha-L-rhamnosidase six-hairpin glycosidase"
FT /evidence="ECO:0000259|Pfam:PF17389"
FT DOMAIN 817..888
FT /note="Alpha-L-rhamnosidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF17390"
SQ SEQUENCE 917 AA; 104031 MW; BA3E3364A0288499 CRC64;
MQISRCGIHG FHEVLGIDTD EIRFYWAIES EDKNATQVFY RIVVTTDAAE LESDRPDISK
LVWDSGRVES NEQRNILCKP STGFQSTTSH FWRITVWDQT NNAHHTAANH FFTAYPRSHL
LTPYSMNQTY MPHSSLIFKS WFEDEANRWK AVWIGDGGDK PIYLRKAFEL AQKPVRAILF
ASGLGHFNMS VNGQPASDHR LDPGWTNYHR RVQFTSYDVT GHLDSGHNAL GVHLGNGFYA
GDKGGDDRFF WPMYEDNTYV RYGNELCFFG ELHLFYGNGE HTVLISDGSW KVSKSATTLA
NIYASENHDR RRYPSGWDSA SFDDTEWAPA KPLTGPRGHI YYQTQPPVVL HETFQPRKVH
SPRKGVVCYD LGQNASTMVK IAVEGAAGSE IIVRYSETVR EDGTVLMPDP LFKEFETGVF
SRIILSGTGQ PEIWEPDFSF TSARYIQVEG VSLDAGSGLP VIHSAVGRHI SSAARKLGHM
TTDKADVNSL LSALYWSFSS NLFSYHTDCP QIEKFGWLEV THLLAPATQY IRDMESLYTK
ILDDILDSQE PSGLVPTMAP EIRYMCGPLH DTITWGCALC LLPDILRQYY GSTHVIPKVY
PAAVQYMEYM KTKERKGGLI EHGLGDWGRG IAFGNNQANI ETAVYYRCLQ CVEMMAHELG
KLQEAEKFKQ WSARIYDVYN QHLLVTDDQS RPYAYYTSLD NYPERDCDAI AQAMALQFGL
VPTKFHSDVM AAFLDDVADG KIRAGEIGLR FLFNTLADAK RPDLVLQMVR QEEHPSYMRF
LRRGETTLLE FWQDECRSKC HDMLGTIYEW FYAAVLGLKP VSEAYRTFEI NPPYESEFDH
VKGSVDSPYG LILIEFMRTD KTSVKLDLQV PFGTTAIVKL PADMRQAEIG SAKEAIKSVH
GRELELSHGS YTVFVQL
//
